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The role of chance in evolution
Sandwalk Strolling with a skeptical biochemist More Recent Comments Thursday, October 18, 2018 I highly recommend this brief editorial by Naruya Saitou:…
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3 days ago
Vegan Winter Lentil Stew
Vegan Winter Lentil Stew $5.08 recipe / $0.64 serving Jump to Recipe I’m already declaring THIS my favorite recipe of the winter of 2018/2019, and we haven’t…
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3 days ago
Twitter
RT : Presentation help time.

Here's a helpful scale to use for your poster!

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3 days ago
Computer Stories: A.I. Is Beginning to Assist Novelists
Robin Sloan, in his office in the Murray Street Media Lab in Berkeley, Calif. He is using a computer program he created to help write his latest novel. Credit…
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3 days ago
Twitter
RT : Memories : Magnetic Rose - Studio 4°C - 1995
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4 days ago
Gingerbread Cut-Out Cookies | Isa Chandra Moskowitz
Gingerbread from back in the day What a difference 4 years makes. When Terry and I made these Gingerbread Punks for a lost episode of Post Punk Kitchen, we…
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4 days ago
Q&A with Elizabeth Iorns and Dan Knox, Cofounders of Science Exchange
We put together a list of the top YC companies by valuation as of October 2018. You can see that list at https://ycombinator.com/topcompanies . Here’s a Q&A…
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4 days ago
This Is The Real Reason We Haven’t Directly Detected Dark Matter
Physicists assemble the LUX (Large Underground Xenon) detector, which was one of the world’s most sensitive searches for the direct detection of dark matter…
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4 days ago
Felix Salmon
Felix Salmon Chief financial correspondent (Axios) Posted October 18, 2018 Filed under: journalist mac podcaster Who are you, and what do you do? My name is…
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4 days ago
Partition Tournament Final Results
Our Protein Design Partition Tournament concluded yesterday. In the final week, we ran four regular puzzles for the tournament front-runners, so that the…
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4 days ago
Twitter
RT : Yet a new journal fron Randy Schekman. Presented at the 2018 Golgi meeting.
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5 days ago
Electron Density results and challenge!
We wanted to give you an update on the latest Cryo-EM puzzles. In Puzzle 1554 we gave you 5 starting models to work with, and these were the results: For all…
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5 days ago
docopt for dummies
Parsing command line arguments is an annoying piece of boilerplate we all have to do. Documenting our code is either an absolutely essential part of software…
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5 days ago
A Rabbit, One Wedding & Two Funerals — I Love Typography %
October 17, 2018 Last week we visited mid-sixteenth-century Zurich to take a look at an intriguing encyclopedia of animals in Unicorns, Frogs & the Sausage…
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5 days ago
Life Got You Down? Time to Read The Master and Margarita
‘“And what is your particular field of work?” asked Berlioz. “I specialize in black magic.”’ If many Russian classics are dark and deep and full of the horrors…
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5 days ago
Twitter
RT : Revolutionary Girl Utena - Chiho Saito - 1996/1997
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6 days ago
Andrew W.K. on Autumn
I moved to Michigan from California when I was four years old. I got a new house, a new school, and, eventually, some new friends. But perhaps best of all, I…
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6 days ago
Twitter
RT : Starting the 3rd protein Crystallography course: from theory to practice. Future macromolecular crystallographers w…
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6 days ago
Smoky Maple Roasted Acorn Squash
Smoky Maple Roasted Acorn Squash $1.66 recipe / $0.42 serving Jump to Recipe I know, I use smoked paprika in everything , but that’s because it makes everything…
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6 days ago
Why it’s hard to read the time on Infograph
Quick, what time is it? If that took you a bit longer than usual to tell the time on the Apple Watch’s new default Infograph face, you’re not alone: John Gruber…
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6 days ago
The Org Chart Test
If you’ve had a 1:1 with me in the last decade you know that once we’re done with our planned agenda that there is good chance that I’ll stand up, walk to the…
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6 days ago
Word of the Day – “Bescheid”
Hello everyone, and welcome to our German Word of the Day, this time with a look at the meaning of Bescheid Now, I spelled that with a capital B which means…
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6 days ago
Past Conditional – Exercise
Hello everyone, and welcome back to the if-est series ever… the series on Conditional. It’s been quite the journey. We learned what the heck I mean by…
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6 days ago
Bellwoods
September 17, 2018 Bellwoods Last week I released Bellwoods — an art game for mobile & desktop that you can play in your browser. The concept of the game is…
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6 days ago
Exploring college major and income: a live data analysis in R
I recently came up with the idea for a series of screencasts: I've thought about recording a screencast of an example data analysis in #rstats . I'd do it on a…
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6 days ago
The Best Scissors For Everyday Use
Scissors are the unsung heroes of office supplies. They are there for us when we need to snip the tags from a new sweater, cut out crafts, or open a package.…
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6 days ago
How to Do an Eyedropper Pen Conversion
Converting a standard fountain pen into an eyedropper pen is a favorite project among fountain pen aficionados. Eyedropper pens are filled by putting ink…
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6 days ago
How to get seasick without leaving your desk
It’s always easy to get caught up in computational work, so let me describe a quick experiment you can do to relieve the boredom. Sit down in your spinny chair…
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8 days ago
A diet guru explains why you should eat dinner at 2pm
There have been two main changes in dietary habits from the 1970s (before the obesity epidemic) until today. First, there was the change is what we were…
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9 days ago
Asterisks in Python: what they are and how to use them - Trey Hunner
There are a lot of places you’ll see * and ** used in Python.These two operators can be a bit mysterious at times, both for brand new programmers and for folks…
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11 days ago
Aaron Edwards
Aaron Edwards Writer, editor (Pop-Up Magazine) Posted October 11, 2018 Filed under: editor mac writer Who are you, and what do you do? I'm Aaron Edwards , and I…
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11 days ago
Portfolio
Hasselblad-Instax A 48-hour project to merge a Hasselblad 500C/M and a FujiFilm Instax 9 Instant photos are magical. They develop before your eyes. You can…
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11 days ago
Kailee McGee
Photo by Rose Olivia Curry. Kailee McGee Artist, writer, filmmaker Posted October 09, 2018 Filed under: artist mac video writer Who are you, and what do you do?…
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13 days ago
How I Erased My Facebook Comments and Likes and Activity
or, How to Delete Your Facebook History Updated - 16th April 2018 I've now released a copy of the tool I used to delete my Facebook history as open source. You…
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14 days ago
Opinion | In Praise of Mediocrity
In Praise of Mediocrity The pursuit of excellence has infiltrated and corrupted the world of leisure. Mr. Wu is the author of “The Attention Merchants: The Epic…
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15 days ago
All-Purpose Garlic Herb Seasoning
All-Purpose Garlic Herb Seasoning $0.28 per batch Jump to Recipe The other day I got a request to create recipes for some simple seasoning blends, like garlic…
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15 days ago
kafka.html
"Infinite Jest: Reviews, Articles,and Miscellany" Laughing with Kafka By David Foster Wallace Harper's Magazine, July 1998 From a speech given by David Foster…
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15 days ago
How to read Kafka: part I by John M. Ellis
K af ka’s stories are famously bizarre and mysterious, and for that reason his readers expect to get help from people who make their living by reading and…
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15 days ago
How not to say the wrong thing
Op-Ed It works in all kinds of crises -- medical, legal, even existential. It's the 'Ring Theory' of kvetching. The first rule is comfort in, dump out. Email…
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16 days ago
What is good color?
i 6 Votes When discussing color, different people have different reactions to the same pictures, be they photos or paintings. Where some enthuse „such great…
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16 days ago
"The Awful German Language" by Mark Twain
The Awful German Language by Mark Twain [This is Appendix D from Twain's 1880 book A Tramp Abroad .This text is basically a HTML conversion of the plain ASCII…
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16 days ago
The Teens Who Rack Up Thousands of Followers by Posting the Same Photo Every Day
@samepictureofatoaster Every day for more than a year, Joey, a 15-year-old high-school student, has logged on to Instagram and posted the exact same photo of…
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17 days ago
A Brief History of Speedrunning - Read-Only Memory
Of all the iD Software games from the early ’90s, I only hazily remember Wolfenstein 3D at best. My mother’s big beige block PC in her upstairs office had it…
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17 days ago
Should you learn C to "learn how the computer works"? • Steve Klabnik
October 2, 2018 I’ve often seen people suggest that you should learn C in order to learn how computers work. Is this a good idea? Is this accurate? I’m going to…
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18 days ago
The Coders Programming Themselves Out of a Job
Gabrielle Lurie / Reuters I n 2016, an anonymous confession appeared on Reddit: “From around six years ago up until now, I have done nothing at work.” As far as…
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18 days ago
Preparing a five minute conference talk: an honest account
On 26 September I had the opportunity to give a short talk at the COSTNET18 conference in Warsaw. I’d never done anything like it before, which made it both…
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18 days ago
Word of the Day – “handeln”
Hello everyone, and welcome to our German Word of the Day. This time we’ll take a look at the meaning and family of handeln But we’ll need some mind bending…
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18 days ago
We’re (still) not being alarmist enough about climate change
What if we had another 9/11, and nothing happened? Living in New York City, the one fantasy sport that everybody plays is real estate; we all like to imagine…
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18 days ago
Walter Parenton
Walter Parenton Video editor (Funimation), illustrator Posted October 04, 2018 Filed under: illustrator mac video Who are you, and what do you do? Hi! My name…
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18 days ago
Why I support Plan S
1. The world spends $10 billion annually on scientific publishing. 2. Most scientific papers are only accessible with subscription, which means they are only…
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18 days ago
‘Sokal Squared’: Is Huge Publishing Hoax ‘Hilarious and Delightful’ or an Ugly Example of Dishonesty and Bad Faith?
Mike Nayna James A. Lindsay, Helen Pluckrose, and Peter Boghossian, the academics who carried out a publishing hoax that targeted scholarly journals R eactions…
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19 days ago
Press release: The Nobel Prize in Chemistry 2018 - NobelPrize.org
"This year’s Nobel Laureates in Chemistry have been inspired by the power of evolution and used the same principles – genetic change and selection – to develop proteins that solve mankind’s chemical problems."
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19 days ago
Unexpected Benefits of Kids Playing with Atari 2600 Games
Unexpected Benefits of Kids Playing with Atari 2600 Games My son has been enthusiastic about video games from a very young age without much prompting. He got…
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20 days ago
Scott Jenson
Scott Jenson Android UX designer Posted October 02, 2018 Filed under: designer interface mac windows Who are you, and what do you do? I research and develop…
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20 days ago
Partition Tournament Update: More Challenges
We are now two weeks into Phase Two of the Protein Design Partition Tournament ! In the Partition Puzzles, challengers continue to find low energy decoys,…
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21 days ago
Tips for a budding Masters Student in Bioinformatics
2nd of October 2018 So I've submitted the thesis, had the viva, gotten the result and it's the end of a two year stint at trying bioinformatics. How did it go?…
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21 days ago
Where Vim Came From
I recently stumbled across a file format known as Intel HEX. As far as I cangather, Intel HEX files (which use the .hex extension) are meant to makebinary…
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21 days ago
On open peer review
Among the things that make science unique is the fact that scientists agree on what they say. There can be disagreement, but it is always understood as a…
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21 days ago
How to Talk to the Women in Your Life Right Now
Photo Illustration by Alicia Tatone It's been an exhausting week of news. For women, nonbinary people, and survivors of sexual abuse, this week has been…
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21 days ago
Aminoglycoside Antibiotics and Resistance
PDB-101 Current Feature By Category By Date By Title About Molecule of the Month Image Download Browse Paper Models Flyers, Posters & Other Resources Videos…
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21 days ago
Chindōgu, el arte del invento inútil
Chindōgu 珍道具 (珍: poco común, 道具: herramienta) es el arte japonés de inventar herramientas cuya originalidad es muchas veces —aunque no todas— más importante que…
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21 days ago
Two views of earthquake occurrence in the Bay Area
This article has a nice description of earthquake occurrence in the San Francisco Bay Area. A few quantities are of interest: when the next quake occurs, the…
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22 days ago
best left unsaid
There are times in life when things are best left unsaid. So you bite your tongue or someone bites it for you. Either way, you are silenced and no - or less -…
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22 days ago
Maruman Mnesmosyne: A Comprehensive Guide
Maruman Mnemosyne is the quintessential notebook series for professionals. Named for the Greek goddess of memory and mother of the nine muses, Maruman Mnemosyne…
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22 days ago
Things That Help Us Relax
Photo: Kyle Fitzgerald Health & Fitness Personal Care At Wirecutter, we want to help our readers by figuring out the right stuff to get to lead balanced lives.…
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22 days ago
The long-term effects of good (and bad) customer service policies
At home we’ve been buying some new stuff for the bedroom. This is admittedly a very boring part of life, but it can be an expensive proposition, so it pays to…
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22 days ago
You know what’s cool? Turning down twenty billion dollars
Brian Acton does not sound like the happy, fulfilled guy the stereotype of billionairedom would have you believe. He sounds like someone racked with regret,…
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22 days ago
Stephen Hackett
Stephen Hackett Co-founder, Relay FM Posted September 27, 2018 Filed under: mac podcaster writer Who are you, and what do you do? I am the co-founder of the…
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24 days ago
Exclusive: WhatsApp Cofounder Brian Acton Gives The Inside Story On #DeleteFacebook And Why He Left $850 Million Behind
W hatsApp cofounder Brian Acton, 46, sits in a cafe of the glitzy Four Seasons Hotel in Palo Alto, California, and the only way you’d guess he might be worth…
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24 days ago
Solving the genome puzzle
E vie Walker sits on her mother’s lap, playing a game she never grows tired of: turning her mother’s hand over and over, stroking and examining it. When she…
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25 days ago
‘This guy doesn’t know anything’: the inside story of Trump’s shambolic transition team
C hris Christie noticed a piece in the New York Times – that’s how it all started. The New Jersey governor had dropped out of the presidential race in February…
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25 days ago
Word of the Day – “peinlich”
Hello everyone, and welcome to our German word of the Day. This time, we will talk about … my pee stain. I was in a café, a very crowded café I should say, and…
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25 days ago
Allison Parrish
Allison Parrish Poet, programmer, professor, game designer Posted September 25, 2018 Filed under: designer game mac poet professor Who are you, and what do you…
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25 days ago
Fundamentals of Software Sustainability
This blog post is intended as companion text for a talk I gave at the September 2018 NumFOCUS Project Forum in in New York, though I also hope it stands on its…
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26 days ago
Illustrating “It Doesn’t Have to Be Crazy at Work”
Take a look behind the scenes at the illustration process for Jason Fried and DHH ’s new book, “ It Doesn’t Have to Be Crazy at Work ” . Back story Every essay…
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26 days ago
Made in France stereotypes
France is on my mind lately, as I prepare to bring my dataviz seminar to Lyon in a couple of weeks. (You can still register for the free seminar here .) The…
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26 days ago
When Was the Last Time You Replaced Your Bike Helmet?
If you ride a bike and wear a helmet, you may have heard at some point—perhaps for vague reasons having to do with foam degrading, or maybe corrosion from salt…
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26 days ago
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