C60 fullerene is widely reported to reduce pain due to inflammation

See also
* doubled lifespan in rats - https://www.reddit.com/r/Nootropics/comments/2uyzls/anyone_tried_c60_fullerene/

* fixed multiple sclerosis and mushy paw in cats - https://www.reddit.com/r/longevity/comments/52np0q/c60_and_olive_oil_me_and_the_cats/
life  extension  longevity  substance  supplement  2read 
16 hours ago
Meh. No questions about ergonomics, e.g. window switching.
choose  select  Linux  distro 
Eloston/ungoogled-chromium: Google Chromium, sans integration with Google
Bringing back the "Don't" in "Don't be evil"

ungoogled-chromium is Google Chromium, sans integration with Google. It also features some tweaks to enhance privacy, control, and transparency (almost all of which require manual activation or enabling).

ungoogled-chromium retains the default Chromium experience as closely as possible. Unlike other Chromium forks that have their own visions of a web browser, ungoogled-chromium is essentially a drop-in replacement for Chromium.
Chromium  fork  privacy  open-source  against  tracking  surveillance 
2 days ago
Linux MATE annoyances in the first minutes of usage
Display tearing
No Super+0..9
1px window resize borders
No Lenovo Thinkpad X1C trackpoint support
against  open-source  Linux  MATE  desktop  environment 
2 days ago
Study Suggests Medical Errors Now Third Leading Cause of Death in the U.S. - 05/03/2016
10 percent of all U.S. deaths are now due to medical error. Third highest cause of death in the U.S. is medical error

more than 250,000 deaths per year are due to medical error in the U.S.

According to the CDC, in 2013, 611,105 people died of heart disease, 584,881 died of cancer and 149,205 died of chronic respiratory disease — the top three causes of death in the U.S. The newly calculated figure for medical errors puts this cause of death behind cancer but ahead of respiratory disease.
USA  healthcare  system  death  cause  against  hospital  doctor  medic 
3 days ago
Pika - a searchable catalog of modern 'module' esm packages on npm
Search NPM for packages that publish ES modules with `export`. Luxon shows up for "date".
Node.JS  new  module  package  search 
4 days ago
Psilocybin 'Magic Mushrooms' Can Help People Quit Smoking - The Atlantic
12 out of 15 quit smoking after 1-2 psilocybin trips (the typical success rate is 35%)

"depression and addiction both involve a narrowing of vision—a tunnel that it takes a profound experience to suck someone out of. Psilocybin, he says, can foster something called cross-talk between regions of the brain that don’t normally communicate. Cross-talk, in turn, is associated with novel ways of looking at problems."

When tripping, people are “dealing with stuff they haven’t dealt with in years or decades”

"Johnson cautions that his study doesn’t mean people should take mushrooms on their own to cure various ailments, or at all. His intervention was tightly controlled and guided. Mushrooms and other hallucinogens carry the risk of “behavioral toxicity”—the scientific term for trying dangerous feats while high.

Besides, he says, people don’t necessarily need to take hallucinogens to break free of their destructive brain patterns. It can happen with any mystical life experience—the kind that changes everything that comes afterward. Living in a foreign country, giving birth to a child, and even falling in love can all approach the brain-rearranging power of psychedelics, at least for some people."
shrooms  psilocybin  addiction  cure  quit  smoking 
5 days ago
Metabolic impact of protein feeding prior to moderate-intensity treadmill exercise in a fasted state: a pilot study | Journal of the International Society of Sports Nutrition | Full Text
25g casein protein consumed fasted 30 minutes before treadmill cardio exercise at 60% reserve heart rate resulted in more fat burn in 11 young men.

Better than 25g of maltodextrin.

2018 study.
fat  weight  loss  exercise  workout  study 
5 days ago
Two startups offer an easier way to get a green card
TurboTax for green cards: Boundless and Borderwise. $500-$750 to apply for a Green Card and access legal advice. How messed up immigration has become under the Trump administration.
immigration  USA  visa 
5 days ago
Medical Tourism Statistics & Facts | Patients Beyond Borders
How much can you save?

Using US costs across a variety of specialties and procedures as a benchmark, average range of savings for the most-traveled destinations:

Brazil: 20-30%
Costa Rica: 45-65%
India: 65-90%
Malaysia: 65-80%
Mexico: 40-65%
Singapore: 25-40%
South Korea: 30-45%
Taiwan: 40-55%
Thailand: 50-75%
Turkey: 50-65%
medical-tourism  cost  statistics 
6 days ago
Capacitor: Universal Web Applications
Invoke Native SDKs on iOS, Android, Electron, and the Web with one code base. Optimized for Ionic Framework apps, or use with any web app framework.
app  cross-platform  web  native 
6 days ago
setTimeout as a Service
Check if your web app blocks if the server is slow
http  debug  webdev 
7 days ago
Wall Street Rule for the #MeToo Era: Avoid Women at All Cost - Bloomberg
just hiring a woman these days is “an unknown risk.” What if she took something he said the wrong way?

Across Wall Street, men are adopting controversial strategies for the #MeToo era and, in the process, making life even harder for women.

Interviews with more than 30 senior executives suggest many are spooked by #MeToo and struggling to cope. “It’s creating a sense of walking on eggshells,”

This is hardly a single-industry phenomenon, as men across the country check their behavior at work, to protect themselves in the face of what they consider unreasonable political correctness -- or to simply do the right thing.

For obvious reasons, few will talk openly about the issue. Privately, though, many of the men interviewed acknowledged they’re channeling Pence, saying how uneasy they are about being alone with female colleagues, particularly youthful or attractive ones, fearful of the rumor mill or of, as one put it, the potential liability.

A manager in infrastructure investing said he won’t meet with female employees in rooms without windows anymore; he also keeps his distance in elevators. A late-40-something in private equity said he has a new rule, established on the advice of his wife, an attorney: no business dinner with a woman 35 or younger.
#MeToo  backfire  sexual  harassment  political  correct  women  workplace  office 
7 days ago
Node GH - All the power of GitHub in your terminal
Manage issues and pull requests from the command line
GitHub  tools 
7 days ago
uBlock Origin Extra - Chrome Web Store
Counter anti-ad-blocker technology used by some sites.

Problem is, that tech, Instart Logic, is considered by the extension author to be "extremely hostile to users, even those NOT using a content blocker, as it allows third-party servers to read/write cookies even if a user chose to block 3rd-party cookies"
against  counter  adblock  prevention 
8 days ago
What floppy-eared foxes taught us about how animals become tame - The Washington Post
[[Within the first decade of the fox domestication experiment, the animals were not only markedly tamer, offering up their stomachs for belly rubs, but some of them had curly tails and mottled fur.

Select animals based on tameness and only tameness, and many of the traits that make up the domestication syndrome come along for the ride.

And at this point, you may be wondering about America’s other favorite pets: cats. Why they possess some traits of the syndrome but still have pointy ears, we don’t know. One speculative possibility is rooted in the idea that cats’ bond to humans, and their reliance on us, is weaker than in dogs, and that even during the domestication process, cats probably had to fend for themselves more than dogs. Natural selection, according to this idea, may have strongly favored pointed ears for the benefits they provide during hunting.]]
domestic  silver  fox  characteristics  traits  phenotype 
8 days ago
Canny: Customer Feedback Management Tool
Simplistic alternative to UserVoice, GetSatisfaction etc.
+ extremely simply to sign up with GitHub and upvote an idea
- no downvoting
- stupid lack of scrollbars on short lists of planned/complete features, WTF - https://requests.requarks.io/

Used by wiki.js.org.
product  customer  feedback  management  system  tool 
8 days ago
Slimbook PRO 13" Aluminium 1.3kg Ultrabook - SLIMBOOK Ultrabook, laptops, computers
Several models of ultraportable Linux laptops around 1.3kg / 2.8lbs. Configurable with up to 32GB RAM, secondary storage etc.

Assembled in Spain, with Spanish sprinkled throughout the site.

Much lower prices than the Dell XPS 13 Developer Edition (https://www.zdnet.com/article/2017s-best-linux-laptop-the-latest-dell-xps-13/), which also apparently has auto-brightness impossible to turn off (http://disq.us/p/1q2c1jp).

See also Purism and Tuxedo Computers.
Linux  laptop  notebook  Dell  Thinkpad  Lenovo  alternative 
9 days ago
Intel Management Engine - Wikipedia
See the talk page. Intel's denial is a "non-denial denial".

Purism disables AMT, but unclear about ME.

See also https://en.wikipedia.org/wiki/Intel_Active_Management_Technology
CPU  surveillance  backdoor  Intel  awareness 
9 days ago
Purism, SPC - Wikipedia
Privacy-oriented laptops and smartphones with hardware kill switches, running entirely FOSS. FSF endorsed PureOS.
laptop  notebook  Android  phone  hardware  privacy  security  awareness 
9 days ago
Custom-built matte screen Linux laptops assembled in Germany
Very beefy specs in ~3lbs: 32GB RAM, 2 SSDs, USB-C, 12h battery, fanless, optional discrete graphics etc.

They've released an open-sourced fan control app for Linux:
Linux  laptop  notebook  awareness 
9 days ago
Keyboard acoustic eavesdropping attack
Capture passwords while the victim types them on a Skype call, or by placing an accelerometer (e.g. ordinary iPhone) on the same table, or by pointing a laser at the back of a laptop etc.

"The following figures depict a possible S&T scenario: first, the attacker and the victim VoIP call each other (in our example, a Lawyer's firm as victim, and our Research Group as attacker). Then, the victim proceeds to inadvertentely type sensitive information during the call (in our example, their Gmail ID and password). With the keyboard noise collected through VoIP, the attacker is then able to recover the full typed text of the victim."


More attack vectors at https://security.stackexchange.com/questions/23322/keyboard-sniffing-through-audio-recorded-typing-patterns

Twitter thread: https://twitter.com/feross/status/1068038193868460032
audio  keylogger  sniff  keyboard  password  attack  security  acoustic  cryptanalysis  awareness 
11 days ago
5 Principles for Making Better Life Decisions | Mark Manson
the sweet spot in decision-making is to find the short-term failures that enable the huge long-term successes to happen

Most people look at each decision as a single roll of the dice. They don’t think about the fact that life is a never-ending sequence of dice rolls. And a strategy that loses a lot per roll can actually make you a big winner in the long run.

* Be excessively bold in your dating life, stating exactly who and what you want, knowing that the vast majority of people will not be compatible.
* Buy a bunch of difficult books expecting that most of them won’t be useful or comprehensible to you, but also that, occasionally, one will completely change your life.
* Say yes to every invitation knowing that most of the events/people will be kind of dull and you’ll just go home early, but that occasionally you’ll meet someone really important or interesting.

Most of us are afraid of failing or screwing something up. But we rarely ask, “Would I regret that failure?” If the answer is “no,” then that is absolutely a risk you should pursue.

I personally know a lot of people—myself included—who ultimately made big life decisions largely based on the path of least regret. These decisions are almost always described as the best decisions they’ve ever made. Instead of basing your decisions around success/failure, or happiness/pain, base them around regret avoidance. Our regrets are usually the best measurement of what is actually valuable to us in the long-run.

Writing things down is a simple but powerful way to clarify everything that’s swirling around in your head. I get emails from readers all the time with long screeds about the issues in their lives only to have them say at the end that they don’t need a reply because writing it all out was so cathartic and revealing for them. Rereading what you write reveals your own logic (or lack thereof). And it often reveals new perspectives you hadn’t considered.

Write down:
* short- and long- term pros and cons
* "What is your motivation behind the decision and is that a value you want to cultivate in yourself? For example, are you buying that car because you would genuinely benefit from owning it, or because you’re trying to impress the people around you? Are you trying to start a business because you enjoy the challenges and ups and downs of making your own way, or are you jealous of your friends that have successful businesses and feel like you don’t quite measure up to them? If you identify some ulterior motives when weighing a decision, stop and ask yourself if your intentions align with who *you want to be*".
howto  decide  life  advice 
11 days ago
Watch "7 Reasons Ben Shapiro Is So Dominant In Debates" on YouTube
Snuck premises - "killing babies is what I have a problem with" in an abortion debate
Push for specifics - don't debate general ideas
debate  howto  persuasion 
18 days ago
How to start meditating, by Matt Bell on Facebook
[[For the first time in my life, I've managed to start meditating regularly. I've been able to meditate on 80% of days for about 2 months and I'm actually starting to see results from it.

I've tried to do this maybe 5 times over the last decade and have always failed to keep doing it after the first couple of days.

In case it is useful to you all, I figured I'd write up what worked:

- I read the first few chapters of The Mind Illuminated, a book on meditation written by a neuroscientist who sets up a clear series of 10 stages to progress through. I've mostly been following the techniques in the book. I've been supplementing it with a non-meditation-related book, Behave, by Robert Sapolsky, which talks in detail about how various parts of the prefrontal cortex mediate attention. This helps me better mentally model what happens when I meditate.
- I set extremely achievable goals for meditation length (starting at 5 minutes) and only lengthened meditation length by a couple of minutes when the session seemed short and I wanted more time. I'm currently at 16 minutes. I think most meditation guides make a huge mistake when encouraging people to start with 15-30 minutes. This length is a huge pill for beginners to swallow, and prevents people from establishing a regular practice, which is usually the biggest barrier to success.
- I focus attention on the sensations of breath at the tip of my nose (as described in the TMI book), and I count breaths to get a sense of how long I pay exclusive attention before a stray thought captures my attention.
- I don't beat myself up over periodic stray thoughts but instead see them as a chance to sample what sorts of signals emerge when the mind creates an open space. This "being a scientist of your own mind" reframing is crucial; otherwise meditation seems like an unpleasant chore.
- I also don't beat myself up over missing a day. It's like exercise; more is better, but missing a day is not a tragedy or a sign of weakness.
- I have a social accountability spreadsheet where I note my meditation sessions in a google doc that someone else is also looking at and using for things she wants to track and have accountability for.

At this point, I've noticed I can usually maintain stable attention on the breath (with occasional fleeting thoughts that I usually don't attach to) for a few minutes at a time.]]
meditation  howto 
19 days ago
BookWithMatrix - Book flight itineraries from ITA Matrix
"We've used Matrix to find $350 business-class tickets to China, multi-leg trips to use in combination with miles to travel Southeast Asia, and the best times to visit our significant others in the US, and would love to make the process of finding great trips easier."
cheap  plane  flight  tickets  travel  airline  airplane 
19 days ago
GitHub - yairEO/tagify: lightweight, efficient Tags input component in Vanilla JS / React
[Googler-maintained app] "is awfully slow to add a list of items. Looking at traces, it seems like selectize.js is the thing that's dragging it down. A ton of forced layouts, as well as other busywork. Is that a known issue? Is there a decent alternative?"
tags  input  JavaScript  library 
20 days ago
Low-carb diets cause people to burn more calories | EurekAlert! Science News
Not all calories are the same.

From another article:

“This feeding study, as the longest and largest to date, provides support for the carbohydrate-insulin model and makes a credible case that all calories are not metabolically alike,” said Harvard professor and endocrinologist at Boston Children’s Hospital David Ludwig, one of the authors of the new paper. “These findings raise the possibility that a focus on carbohydrate restriction may work better for long-term weight loss maintenance than calorie restriction.”

The study, which cost $12 million to complete, found that just calorie-counting doesn’t necessarily mean that you will automatically lose weight.
calorie  intake  diet  study  weight  loss  best  ketogenic 
21 days ago
"Howlception" on YouTube
Howlin' through the tubes
video  fun  howl  dogs 
23 days ago
US has spent $5.9 trillion on Middle East, Asia wars since 2001: Study
That means almost ONE BILLION DOLLARS spent PER DAY.

"The U.S. wars in Afghanistan, Iraq, Syria and Pakistan have cost American taxpayers $5.9 trillion since they began in 2001.

The figure reflects the cost across the U.S. federal government since the price of war is not borne by the Defense Department alone.

The report also finds that more than 480,000 people have died from the wars and more than 244,000 civilians have been killed as a result of fighting. Additionally, another 10 million people have been displaced due to violence."
USA  war  cost  awareness 
23 days ago
Implement REGEX.* function(s) in LibreCalc
My successful advocacy to implement a REGEX search function in LibreOffice Calc. Responded to arguments as to why a REGEX function would be a bad idea and convinced the contributors to implement it.
Dascalescu  advocacy 
24 days ago
Algorithmia - Deploy AI at Scale
"Want to find the right algorithm for your project? You’ve come to the right place. We don’t just host your models: we’ve got a marketplace of over 5,000 algorithms for you to utilize. They’re powered by a community of over 70,000 amazing developers from all over the globe."
AI  ML  machine-learning  model  hosting  SaaS  algorithm  marketplace  store  search 
24 days ago
Psychedelic psilocybin therapy for depression granted Breakthrough Therapy status by FDA
"This latest step from the FDA, to offer psilocybin a Breakthrough Therapy designation, is a quietly extraordinary move from the federal agency, implicitly suggesting this previously stigmatized drug may have beneficial clinical uses."

Source: https://www.prnewswire.com/news-releases/compass-pathways-receives-fda-breakthrough-therapy-designation-for-psilocybin-therapy-for-treatment-resistant-depression-834088100.html
shrooms  mushrooms  depression  therapy  cure 
25 days ago
The Case Against Quantum Computing - IEEE Spectrum
A useful quantum computer needs to process a set of continuous parameters that is larger than the number of subatomic particles in the observable universe.

The huge amount of scholarly literature that’s been generated about quantum-computing is notably light on experimental studies describing actual hardware. The relatively few experiments that have been reported were extremely difficult to conduct
against  quantum  computing 
26 days ago
Compare moment with luxon, or even better, date-fns
measure  npm  package  library  size  JavaScript 
26 days ago
6 Public Speaking Tips To Hook Any Audience - YouTube
Text version at https://www.charismaoncommand.com/oral-presentation-tips/

You have 10 seconds to capture the attention of the audience. Don't tell them what you'll be talking about.

Use a prop or provocative question

Create dialog - get your audience to interact, speak, or move during the presentation

Use humor within the first minute. Leave space for the audience to laugh or ponder (use silence).

Tell a story

Use present tense instead and speak in the second person

Perform - public speaking is theater

Leave the audience with a thought-provoking idea or a way to take action - at the end. Tie up stories and loop back to a point.

Analysis of https://www.youtube.com/watch?v=Iqq1roF4C8s
public  speaking  howto  video  charisma 
26 days ago
Cialdini interview on Pre-suasion
Prime the target. Examples:

* job interview - ask the interviewer, "What was it about my qualifications that made you attracted to my candidacy"
* asking women for phone numbers in random places - do it in flower shops, because they prime the idea of romance
* consultant: show proposal and fee, and add "As you can see, I won't be able to charge you a million dollar for this" (comparison/anchoring)
cool  influence  Cialdini  video  sales  tactics 
26 days ago
9 Air-Cleaning Houseplants That Are Almost Impossible to Kill
Based on 1989 NASA study. Snake plants remove benzene, formaldehyde, trichloroethylene, and xylene. Maximize the root-soil area exposure to air.

Original study at http://ntrs.nasa.gov/archive/nasa/casi.ntrs.nasa.gov/19930073077.pdf
plant  clean  indoor  air  pollutants 
28 days ago
Metformin Is a Direct SIRT1-Activating Compound | | LEAF
Aging causes levels of NAD+ to fall. NAD+ is needed to trigger SIRT1 expression which is beneficial to health and metabolism.

Metformin is able to compensate for the age-related fall of NAD+ and trigger SIRT1 directly. So Metformin appears to resist the aging process by keeping the metabolism working and reducing inflammation by activating SIRT1.
life  extension  metformin 
29 days ago
thirdhome - Google Search
Sharing luxury second houses as vacation homes. Put yours on, and travel to others in the network, for free.
luxury  Airbnb  travel  deluxe 
29 days ago
Scientists accidentally create mutant enzyme that eats plastic bottles | Environment | The Guardian
"However, currently even those bottles that are recycled can only be turned into opaque fibres for clothing or carpets. The new enzyme indicates a way to recycle clear plastic bottles back into clear plastic bottles, which could slash the need to produce new plastic."
enviornment  plastic  recycle  bacteria 
29 days ago
Corporate America's blockchain and bitcoin fever is over - Axios
Mentions of blockchain in SEC earnings dropped from 150+ in Q1 2018 to 35 in Q4
hype  against  blockchain  cryptocurrency 
4 weeks ago
Celine's laws - Wikipedia
The greatest threat to national security is national security

All but the entity at the very top of the hierarchy have an incentive to tell their superior what they want to hear, instead of the truth. This makes the top entity not see the truth and persist in their obsession.

An honest politician is the worst because they enact freedom-restricting laws
politics  laws  rules 
4 weeks ago
Top 3% of U.S. Taxpayers Paid Majority of Income Tax in 2016 - Bloomberg
"The top 1% paid a greater share of individual income taxes (37.3%) than the bottom 90% combined (30.5%).

the bottom 50% paid 3%"
USA  progressive  tax  income  inequality 
4 weeks ago
Newly Unsealed Documents Show Top FDIC Officials Running Operation Choke Point
"For those unfamiliar, Choke Point consisted of bureaucrats in several independent federal agencies taking it upon themselves to shut legal businesses – such as payday lenders and firearms dealers – out of the banking system. Given the nature of the U.S. regulatory framework, this operation was easy to pull off.

Officials at the Federal Deposit Insurance Corporation (FDIC), for instance, simply had to inform the banks they were overseeing that the government considered certain types of their customers “high risk.” The mere implication of a threat was enough to pressure banks into closing accounts, because no U.S. bank wants anything to do with extra audits or investigations from their regulator, much less additional operating restrictions or civil and criminal charges."
USA  political  abuse  against  FDIC  banks  awareness 
4 weeks ago
Chrome OS: connect to the Android runtime
If your device is in developer mode, you can run apps locally on your Chromebook. Use Android settings to enable adb debugging. Then open the terminal and connect to the local Android runtime:

$ adb connect
Chrome-OS  ADB  connect  Android 
4 weeks ago
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