asterisk2a + telomere   22

How burnt toast and roast potatoes became linked to cancer | Science | The Guardian
dosage/exposure amount debate - not applicable to carcinogens. see nutritionfacts.org // Törnqvist counters this argument with the observation that, although some chemicals have a minimum threshold concentration below which they are not dangerous at all, this is not the case for DNA-damaging chemicals, known as carcinogens. “With chemicals that damage DNA it’s a linear dose response, so even the smallest dose contributes to the risk,” she said. “There is no threshold dose for the effect.”
Cancer  carcinogen  carcinogenic  Public  Health  DNA  telomere  acrylamide  toxicity  inflammation  toxic 
january 2017 by asterisk2a
'Superhero DNA' keeps diseases at bay
Large numbers of studies have tried to understand these mutations by looking at people who become ill.
But the international team of researchers tried the opposite approach - searching for people harbouring damaging mutations but who remain healthy. [...] "Study the healthy, don't just study the sick."
However, this is where the tantalising story ends. The scientists were unable to go out and find the lucky 13 because of the consent rules signed when their DNA sample was taken.
It means they do not know what is protecting them against disease. [...] "Because of the inability to confirm the source or validity of the variants and the inability to recontact the individuals, this paper does not constitute a proof of principle," [ means they have to do a large-scale study especially for this kind of research ]
genetics  epigenetics  medical  advances  DNA  DNA  damage  telomerase  telomere  telomeres  Genome  sequencing  genomics  23andme 
april 2016 by asterisk2a
Stem cells 'link' to repeat miscarriages, say scientists - BBC News
[ is this a western phenomenon? sick population? not africa, not some parts of japan? ] Accelerated ageing "In fact, this may be the only way to really prevent miscarriages in these cases." The team found a shortfall of stem cells was the likely cause of accelerated ageing of the womb lining which resulted in the failure of some pregnancies. The lining has to renew itself each cycle and this renewal capacity is dependent on the resident stem cell population. Prof Brosens said: "Cultured cells from women who had had three or more consecutive miscarriages showed that ageing cells in the lining of the womb don't have the ability to prepare adequately for pregnancy." [...] "The real challenge now is to develop strategies to increase the function of stem cells in the womb lining," she said. The team will soon start piloting new interventions to improve the womb lining, she said. [ diet and lifestyle? ]
premature  ageing  chronic  diseases  telomere  genetics  epigenetics  sick  population  health  crisis  miscarriage  IVF  female  fertility  fertility  infertility  assisted  fertility  treatments 
march 2016 by asterisk2a
Overview - Sepsis - Mayo Clinic
More people die of Sepsis (in UK) than from all major forms of cancer (breast, bowel and prostate cancer combined) ~37.000. // In sepsis, the body's immune system goes into overdrive // Is a damaged information system ( of the immune system ) linked to higher cases of sepsis? like MS, autoimmune disease. // [S]lurred speech or confusion, [E]xtreme shivering, [P]assing no urine in a day, [S]evere breathlessness, "[I] feel like I might die.", [S]kin rash or mottled skin. SEPSIS // bit.ly/1JssTiy & wb.md/1lmai4m - deadly rush, out of control case of inflammation spreads across the body. Short-circuit. // Why is still unknown! //&! www.niams.nih.gov/Health_Info/Autoimmune/
inflammation  chronic  low-grade  inflammation  anti-inflammatory  diet  immune  system  autoimmune  disease  autoimmune  response  DNA  gene  expression  telomere  epigenetics  DNA  damage  Leaky  gut  Standard  American  diet-related  disease  Western  pattern  diet  diet  lifestyle  antioxidant  free  radicals  public  health  policy  public  health  cancer  heart  disease  sepsis  septicaemia 
january 2016 by asterisk2a
Will Self: The trouble with my blood | Books | The Guardian
As we walked down the grotty staircase of Guy's Hospital Tower from the consultation where she'd been informed of how radical her surgery would need to be, she turned to me and said: "I'm so lucky. If it was 25 years ago, or I was somewhere else in the world, I'd've just received a death sentence." I was less sanguine – metaphorically speaking. I felt distracted and doomy; I was a dilatory carer – and at times seemingly wilfully inept. I could just about manage the basics: the feeding and dressing of our two younger children, and the forcing upon her of increasingly unwanted cups of tea. Advertisement It didn't help that we seemed to be at the centre of a cancer cluster: one friend was dying of leukaemia in Hammersmith hospital, another was in the process of being diagnosed, a third had had half his throat and jaw chopped out. I fully expected cancer myself. [ Polycythemia vera - mutation of cell X. repair mechanism failed. telomere caps fizzled out. disease of OAP. ]
cancer  chronic  diseases  diet-related  disease  sick  population  health  crisis  premature  ageing  ageing  population  OAP  immune  system  anti-ageing  ageing  telomere  free  radicals  antioxidant  NHS  Standard  American  Diet  western  lifestyle  tobacco  Alcohol  abuse  substance  abuse  food  abuse  heart  disease  diabetes  health  care  health  care  budget  health  care  spending  pattern  anti-inflammatory  western  dietary  cholesterol  public  health  policy  public  health  GP  A&E  demographic  bubble  babyboomers 
january 2016 by asterisk2a
Recorded Webinar: The Dietary Treatment of Cancer - YouTube
High-fat high-protein diets promote cancer. even vegetable fats. and both together is great environment for tumors. // thus 80/10/10 started by Doug Graham. and supported by T Collin Campbell in Whole to focus 80/10/10 macros in a Whole-Food Plant-Based Diet. // But Dr Greger also showed / talked about one study in his nutritionfacts.org videos, that even people threatened with death, are unlikely to change their diet, even if recommended by their treating physician. It's a case by case. Patient Compliance. WHY? Because people grew und and still live in an environment that is rigged against their health.
cancer  Whole  Plant  Foods  Whole-Food  Plant-Based  Diet  Vegan  Standard  American  Diet  alkaline  Western  pattern  anti-inflammatory  Dietary  Fiber  chronic  low-grade  inflammation  chronic  diseases  chronic  stress  IGF-1  insulin  endocrine  system  endocrinology  animal  protein  anabolic  steroid  DNA  telomere  animal  fat  free  oil  Palm  pharmaceutical  industry  pharma  big  pharma  medical  profession  medical  advances  medical  care 
october 2015 by asterisk2a
Chemistry Nobel: Lindahl, Modrich and Sancar win for DNA repair - BBC News
Their work uncovered the mechanisms used by cells to repair damaged DNA - a fundamental process in living cells and important in cancer. [...] DNA is open to an onslaught of different phenomena that can generate defects in our genomes. UV radiation and molecules known as free radicals can cause damage. Furthermore, defects can arise when DNA is copied during cell division - a process that occurs millions of times each day in our bodies. "Cigarette smoke contains small reactive chemicals, which bind to the DNA and prevent it from being replicated properly - so they are mutagens. And once there is damage in the DNA this can cause diseases including cancer," said Prof Lindahl.
inflammation  anti-inflammatory  diet  chronic  low-grade  inflammation  DNA  telomere  premature  ageing  cancer  ageing  anti-ageing  Oxidative  stress  antioxidant  chronic  stress  tobacco  Big  Sugar  Carnism  omnivore  Whole-Food  Plant-Based  Whole  Plant  Foods  Vegan  Standard  American  alkaline  diet  Western  pattern  diet  diet  animal  protein 
october 2015 by asterisk2a
Age of menopause 'controllers' found - BBC News
Damage corrected. Comparing the DNA of nearly 70,000 women allowed the researchers to identify the differences between those starting the menopause early and late. The team at Exeter and Cambridge universities showed that at least two repair mechanisms were involved. The first is used when the eggs are being formed and the woman's DNA is being broken, rearranged and repaired. The second corrects damage, caused by factors such as smoking or alcohol, throughout a woman's life. Both would influence the number of viable eggs a woman has. //&! Whole-Food Plant-Based Diet repairs DNA and telomere shorten slower. It is an anti-ageing diet. Period. - nutritionfacts.org/?s=DNA
telomere  DNA  epigenetics  genetics  premature  ageing  ageing  anti-ageing  Whole-Food  Plant-Based  Diet  carnism  omnivore  Standard  American  Diet  anti-inflammatory  inflammation  chronic  low-grade  inflammation  Western  pattern  dieting  sedentary  lifestyle  lifestyle  lifestyle  medicine  active  lifestyle  medical  profession  medical  research  medical  advances  genome 
september 2015 by asterisk2a
Old before your time? People age at wildly different rates, study confirms | Science | The Guardian
“Already, before midlife, individuals who were ageing more rapidly were less physically able, showed cognitive decline and brain ageing, self-reported worse health, and looked older,” the scientists write. // &! nutritionfacts.org/?s=ageing ie one evidence, whole plant food diet (vegan, no processed foods) mimics caloric restriction, thus lowers speed/progress of aging processes. and animal protein does increase it, as well as processed fast and junk food (mix of fats, sugars, processed carbs without fiber) which hits the insulin pump hard. and evidence has shown that pancreas has limited amount of cells to produce insulin - once they gone, age related diabetes is here; nutritionfacts.org/video/what-causes-diabetes/ // &! PREMATURE AGING does add substantially to rising health care cost to the already established demographic bubble factor.
epigenetics  premature  ageing  anti-ageing  ageing  complexity  unknown  unkown  chronic  stress  stress  Oxidative  stress  antioxidant  Standard  American  Diet  western  pattern  anti-inflammatory  alkaline  Vegan  omnivore  public  health  public  health  policy  health  crisis  sick  population  chronic  diseases  sedentary  lifestyle  western  lifestyle  active  lifestyle  lifestyle  medicine  DNA  telomere  fasting  intermittent  fasting  caloric  restriction  insulin  resistance  diabetes  obesity  epidemic  obesity  overweight  medical  profession  medical  advances  medical  research  demographic  bubble  health  science  well  being  noise  pollution  air  pollution  light  pollution  pollution  toxin  animal  protein 
july 2015 by asterisk2a
The Radical New Science of Longevity - YouTube
min15 diet slows or speeds up ageing. Intermittent fasting ie once a month +3 days. cheat would be juice fast or broth. but here is the kicker, whole food plant based diet (vegan) does mimic parts of fasting, evidence in seen in certain factors that get activated when you really do fast. slowing down the burn rate of the many reactors (cells) we have. slowing down the cell division & thus keeping telomere's intact for longer. see also epigenetics. stress does age u. stress in many forms. same with methionine restriction - ncbi.nlm.nih.gov/pubmed/18789600 - The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy. || min 23:00 chemotherapy does accelerate ageing and shows side effects a decade down the rate. ie higher rate of bone cancer occurrence. // min 41 stem cell therapy, currently used in focused approach vs future of preventative supplementation. ie using own blood plasma injected in face 2 increase collagen production
premature  ageing  anti-ageing  diet  anti-inflammatory  diet  chronic  low-grade  inflammation  chronic  diseases  chronic  stress  cancer  epigenetics  Vegan  Whole  Plant  Foods  Whole  Foods  complexity  telomere  chemotherapy  side  effect  big  pharma  pharma  pharmaceutical  industry  genetics  gene  expression  stem  cell  treatment  stem  cell  stem  cell  cosmetics  stem  cell  therapy  blood  plasma  dementia  Alzheimer 
april 2015 by asterisk2a
Healthy lifestyle and leukocyte telomere length in U.S. women.
Adherence to a healthy lifestyle, defined by major modifiable risk factors, was associated with longer telomere length in leukocytes.

http://en.wikipedia.org/wiki/Telomere
http://en.wikipedia.org/wiki/White_blood_cell

White blood cells, or leukocytes (also spelled "leucocytes"; from the Greek word leuko- meaning "white"), are cells of the immune system involved in defending the body against both infectious disease and foreign materials.
lifestyle  diet  aging  White  blood  cells  health  science  health  telomere 
october 2012 by asterisk2a
The Optimal Diet - NYTimes.com
Dr. Dean Ornish op ed in the New York Times warns about dangers of low carb diets (http://nyti.ms/Pdkpei). I wrote a whole book about it, now online free at:

http://www.atkinsexposed.org/

Perhaps the biggest misconception is that as long as you lose weight, it doesn’t matter what you eat. But it does. Yet being thin and being healthy are not at all the same thing. Being overweight is not necessarily linked with disease or premature death. What you eat affects which diseases you may develop, regardless of whether you’re thin or fat. Some diets that may help you lose weight may be harmful to your health over time.

Vegan Diet + Regular Exercise + Stress Management = risisng probability of Good Health into old age (dying of age, not bc of a disease).

WHAT you eat is as important as what you exclude.
Book  Dean  Ornish  healthcare  health  crisis  Cardiovascular  disease  chronic  diseases  Amphetamines  metabolism  metabolic  rate  chromosome  DNA  telomere  epigenetics  diabetes  prostate  cancer  cancer  inflammation  stress-management  stress  Exercise  overweight  obesity  obesity  epidemic  coronary  artery  disease  coro  heart  disease  health  health  science  nutrition  diet  Atkins 
september 2012 by asterisk2a

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