asterisk2a + hypothesis   19

Do Amish hold clue to preventing asthma in children? - BBC News
The Amish community in the US has long been famous for shunning modern technology and preserving traditional ways of life, using horses for farming and for transport.
Now it appears that their closer contact with animals could have an unexpected benefit - preventing asthma in children.
allergy  asthma  Hygiene  hypothesis 
august 2016 by asterisk2a
Peanut allergy theory backed up by new research - BBC News
The effects of eating peanut products as a baby to avoid the risk of allergy have been backed up by new research. In 2015, a study claimed early exposure to peanut products could cut the risk of allergy by 80%. Now researchers say "long-lasting" allergy protection can be sustained - even when the snacks are later avoided for a year. [...] "I believe that this fear of food allergy has become a self-fulfilling prophecy, because the food is excluded from the diet and, as a result, the child fails to develop tolerance," he told the BBC News website. The researchers used the same children who took part in the 2015 study - half of whom had been given peanut snacks as a baby while the remainder had been fed on a diet of breast milk alone. //&! bit.ly/1SoBDsm
food  allergy  allergy  allergies  hygiene  hypothesis  urbanisation 
march 2016 by asterisk2a
Masters in Business: Yale Professor Robert Shiller (Audio) by Bloomberg View
history has proven again, markets are not efficient long-term // psychology is disreputable in econ department. // cognitive dissonance - justifying X action by looking around ... / Efficient-market hypothesis is a hypothesis for a reason; "it's a half-truth" "sometimes market moves don't reflect market news." // irrational exuberance // book fooled by randomness // 24:00 eugene phama - markets are very efficient, prices reflect all the knowledge out there, just buy the index, don't try to beat the market. buy passive index // don't play poker with your life savings. << robert shiller // 30:00 look at politics science, sociology, psychology - influence markets, people. broader disciplines. economists disregard them. // finance is about manage risk! about being a productive society and progress, and not suffer from boom and bust cycle! + financing activities ie VC gov supported R&D // & gov being a support pillar for all and not picking winners, can't forecast the future!
free  market  marketplace  efficiencies  marketplace  inefficiencies  efficient-market  hypothesis  complexity  human  Wall  Street  crowd  herd  herding  speculative  bubbles  distortion  economic  history  GFC  subprime  book  Robert  Shiller  robertshiller  behavioral  finance  behavioral  economics  finance  corporate  welfare  subsidies  subsidizing  corporate  tax  rate  R&D  Venture  Capital  Angel  Investor  Seed  Round  risk  pension  fund  pension  obligation  401k  public  pension  pension  scheme  pension  marginal  propensity  to  consume  plutocracy  Super  Rich  1%  Greed  oligarchy  self-regulation  disposable  income  discretionary  spending  negative  equity  boom  &  bust  secular  stagnation  shareholder  value  profit  maximisation 
february 2016 by asterisk2a
Human-Neanderthal relationships may be at root of modern allergies | Science | The Guardian
The three genes are among the most common strands of Neanderthal and Denisovan-like DNA found in modern humans, suggesting they conferred an evolutionary advantage. They probably boosted the immune system, since the genes are involved in the body’s first line of defence against pathogens such as bacteria and fungi. Neanderthals and me: we go back a long way Read more But people who carry the three genes seem to pay a price in the form of an overly-sensitive immune system. One study by the US genetics company 23andme found that carriers of the genes were more likely to have asthma, hay fever and other allergies.
allergy  allergies  food  allergy  immune  system  hygiene  hypothesis 
january 2016 by asterisk2a
Asthma: Darmflora entscheidet mit übers Asthma-Risiko - SPIEGEL ONLINE
Die Darmflora hat entscheidenden Einfluss auf die Gesundheit. Eine aktuelle Studie zeigt: Fehlen in den ersten Lebensmonaten bestimmte Bakterien, steigt das Asthma-Risiko deutlich.
Gut  Flora  microbiome  immune  system  autoimmune  disease  autoimmune  response  Leaky  hygiene  hypothesis  endotoxin  chronic  low-grade  inflammation 
october 2015 by asterisk2a
A defense of Dave Morin | PandoDaily
[1bn consumer apps are more rare than lottery winners. period.] But despite it all, he just didn’t win. It’s crushing evidence of just how hard it is to build the next huge consumer Internet sensation. Mock Morin all you want, but pre-launch Google valued Path higher than it likely is valued today. If he was wrong to believe he could build the mobile Facebook, so were some of the smartest people in the Valley. So what did Morin do so wrong? Some parts of his thesis were right, but exact manifestations of that thesis weren’t. People were longing for a mobile social network focused on photos. People were longing for a Facebook-other. Just not the one he created. You can never predict how products will resonate. Did he focus too much on pleasing Valley early adopters while Snapchat and Whisper were resonating with teens, and Whatsapp largely got its legs through an international audience? Perhaps. [ Hypothesis; what do u believe what others dont believe
Dave  Morin  Path  Start-Up  lesson  Start-Up  advice  consumer  product  Design  Product/Market  Fit  Minimal  Viable  MVP  hypothesis  Appification  Snapchat  Instagram  Whisper  Yik  Yak  Secret  single-use  app  mobile  homescreen  user  behaviour  attention  span  Kevin  Rose  Silicon  Valley 
june 2015 by asterisk2a
Great Gut Extinction: Has modern life destroyed our health? - BBC News
Our modern lifestyle is often blamed for the explosion in conditions like asthma, diabetes and obesity - but the evidence that our predecessors didn't suffer such ailments has been hard to come by - until now. [...] The use of antibiotics, processed foods and soap may have led to less diversity in our microbes according to Dr Gautam Dantas from the Washington School of Medicine, one of the researchers who has studied the Yanomami people. [...] "If you upset the good bacteria, it might well be that the immune system of that baby will be ill-educated and respond wrongly to other agents and bacteria."
microbiome  western  lifestyle  western  diet  Standard  American  pattern  diet  antibiotic  resistance  hygiene  hypothesis  autoimmune  disease  autoimmune  response  immune  system  post-antibiotic  era  antibiotics  childhood  development  childhood  parenthood  Leaky  gut  endotoxin  chronic  low-grade  inflammation 
may 2015 by asterisk2a
Bill Gurley schools NYU professor: Uber will be 25x bigger than you think | PandoDaily
[ + long tail use cases and cases that seem in retrospect obvious but currently are foggy (ie owning a car in the city for ppl a luxury good), car ownership deemed inefficient/waste of money; when car is used only ~5% during the day and there are clearly cheaper and if not even more convenient options of daily transportation on offer. ] Gurley, who is one of the smartest and most articulate figures in all of venture capital (and who just happens to be an early Uber investor and board member) laid out a more than 4,500-word argument for why Damodaran underestimated the Uber opportunity by no less than a factor of 25. The Benchmark Capital partner was diplomatic, apologetic even, but that made his dismantling of the professor’s reasoning no less thorough.
Blue  Ocean  Uber  marketplace  efficiencies  marketplace  inefficiencies  value  creation  added  value  intangible  value  Proposition  Core  Product  Proposition  Lyft  Travis  Kalanick  Bill  Gurley  Venture  Capital  frictionless  friction  convenience  management  Product/Market  Fit  consumer  aspirational  experience  Product  Design  Vision  leadership  transportation  public  transportation  urbanisation  urban  planning  city  living  long-tail  longtail  long-term  thinking  long-term  view  hypothesis  incomplete  information  unknown  unknowns  complexity  unintended  consequences 
july 2014 by asterisk2a
Vitamin A and systemic inflammation as protective factors in multiple sclerosis
New findings on multiple sclerosis: An above minimum vitamin A level in the 2nd of five quintiles is associated with a -62% reduced risk of developing multiple sclerosis. Moreover, higher hs-CRP levels (=greater inflammation) in the younger years offer protective effects as well (-64%).

Conclusions: Our results suggest that sub-optimal vitamin A levels may be associated with MS risk. The association between hs-CRP levels and MS risk in young subjects may support the role of the hygiene hypothesis in MS aetiology.

- hygiene hypothesis calls for breast feeding
- hygiene hypothesis calls for less over protective over less cleanliness environment for kids. let kid be kids. what can't kill them, doesn't kill them.

http://www.drweil.com/drw/u/ART02759/facts-about-vitamin-a
- Eat your vegetables and colourful fruits. Not pills. Food.

Years of chronic deficiency leads to chronic diseases.

http://nutritionfacts.org/index.php?s=multiple+sclerosis
parents  autoimmune  response  immune  system  Vitamin  A  autoimmune  disease  parenthood  hygiene  hypothesis  multiple  sclerosis  Vegan  parenting 
january 2013 by asterisk2a

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