asterisk2a + dna   56

Base paired up: study suggests genetic formula to monogamy | Science | The Guardian
The work suggests evolution hit on the same biological trick to make certain species monogamous, by turning up the activity of some genes in their brains, and turning down the activity of others.
genetics  gene  DNA  evolution 
january 2019 by asterisk2a
More male tests needed in cases of repeated miscarriages – UK study | Society | The Guardian
Imperial College scientists find DNA damage in sperm could be undetected cause
fertility  IVF  DNA  damage 
january 2019 by asterisk2a
Painkillers in pregnancy may affect babies' future fertility - BBC News
Edinburgh University found the drugs may also affect the fertility of future generations, by leaving marks on DNA.

Experts said the findings added to growing evidence some medicines, including Paracetamol, should be used with caution during pregnancy.

Researchers stressed advice for pregnant women remained unchanged.

Current guidelines say, if necessary, Paracetamol should be used at the lowest possible dose for the shortest possible time. Ibuprofen should be avoided during pregnancy.

The study looked at the effects of Paracetamol and ibuprofen on samples of human foetal testes and ovaries.
epigenetics  pregnancy  parenthood  DNA  fertility  IVF  damage 
april 2018 by asterisk2a
Internal 'clock' makes some people age faster and die younger – regardless of lifestyle | Science | The Guardian
Scientists have found the most definitive evidence yet that some people are destined to age quicker and die younger than others - regardless of their lifestyle.

The findings could explain the seemingly random and unfair way that death is sometimes dealt out, and raise the intriguing future possibility of being able to extend the natural human lifespan.

“You get people who are vegan, sleep 10 hours a day, have a low-stress job, and still end up dying young,” said Steve Horvath, a biostatistician who led the research at the University of California, Los Angeles. “We’ve shown some people have a faster innate ageing rate.”
DNA  ageing  epigenetics  biology  science  complexity  genetics  gene  microbiome  longevity 
november 2017 by asterisk2a
DNA editing in human embryos reveals role of fertility "master gene" | Science | The Guardian
The failures of fertility treatments could be down, in part, to a reliance on mouse studies, which until now have been seen as the best way to work out the role of genes during embryonic development – and why things sometimes go wrong. The latest work highlights the shortcomings with this approach, showing that the OCT4 gene appears to play a different role in early human embryos than in mice.

“This is in a way unexpected, because of the dogma that the earliest stages of development are common for all mammalian and even some non-mammalian species,” said Dusko Ilic, reader in stem cell science at King’s College London. “The study is another proof that the findings from experimental animal models cannot be always extrapolated to humans.”
chronic  sick  population  premature  ageing  IVF  fertility  DNA  Crispr  mouse  models  Crispr-Cas9  epigenetics 
september 2017 by asterisk2a
Obese women more likely to have babies with serious birth defects, says study | Society | The Guardian
While the additional risk was small for women who were just above the healthy weight range, the progressive increase in risk made the researchers more confident that the link was causal.

Martin Neovius, an epidemiologist at the Karolinska Institute and the study’s senior author, said: “In terms of risk, it is better to be normal weight than overweight and much better to be normal weight than obese.”
UK  USA  chronic  sick  population  obesity  overweight  inflammation  DNA  damage  birth  defect  cancer  immune  system  RNA  gene  expression  western  diet  Standard  American  health  care  demand 
june 2017 by asterisk2a
How burnt toast and roast potatoes became linked to cancer | Science | The Guardian
dosage/exposure amount debate - not applicable to carcinogens. see nutritionfacts.org // Törnqvist counters this argument with the observation that, although some chemicals have a minimum threshold concentration below which they are not dangerous at all, this is not the case for DNA-damaging chemicals, known as carcinogens. “With chemicals that damage DNA it’s a linear dose response, so even the smallest dose contributes to the risk,” she said. “There is no threshold dose for the effect.”
Cancer  carcinogen  carcinogenic  Public  Health  DNA  telomere  acrylamide  toxicity  inflammation  toxic 
january 2017 by asterisk2a
Depression Signposts
progression is silent for 10-20 years. people present late with symptoms. [... like cancer, like heart disease ...] thus medical profession is boxed in to contain damage and or slow disease, not prevent. Damage is already done. // [...] there is some brain damage with chronic major depression [...] currently, there is no marker which pathway to choose to treat Depression best (have to choose options between CBT, talk therapy, medication, etc)... ie prescribing medication that does not work ... // [... ie biomarker in blood for heart attack! ]
neurodegenerative  diseases  Alzheimer  dementia  Parkinson  Parkinson's  disease  Huntington's  disease  neurobiology  neurology  Depression  mental  health  well  being  medical  profession  medical  advances  medical  research  DNA  biomarker  epigenetics  RNA 
april 2016 by asterisk2a
'Superhero DNA' keeps diseases at bay
Large numbers of studies have tried to understand these mutations by looking at people who become ill.
But the international team of researchers tried the opposite approach - searching for people harbouring damaging mutations but who remain healthy. [...] "Study the healthy, don't just study the sick."
However, this is where the tantalising story ends. The scientists were unable to go out and find the lucky 13 because of the consent rules signed when their DNA sample was taken.
It means they do not know what is protecting them against disease. [...] "Because of the inability to confirm the source or validity of the variants and the inability to recontact the individuals, this paper does not constitute a proof of principle," [ means they have to do a large-scale study especially for this kind of research ]
genetics  epigenetics  medical  advances  DNA  DNA  damage  telomerase  telomere  telomeres  Genome  sequencing  genomics  23andme 
april 2016 by asterisk2a
Stop Cancer Before It Starts (Michael Greger, M.D.. 2011)
[ oldschool dr greger ] not only is meat a carcinogen itself, but meat has accumulated pesticides and herbicides, because cows and co eat animal feed full of pesticides and herbicides. but also their loved ones (male chicken, not laying eggs, not putting on meat fast enough for industry to make a bigger profit) are in it, ground up. Even fat trimmings are in animal feed! // breast cancer rates on the rise as meat eating babyboomers come into old age 40-50 and older
dioxin  carcinogen  carcinogenic  GMO  Organic  agriculture  Meat  Industry  Poultry  Industry  Milk  Industry  Fish  Industry  Dairy  Industry  human  breast  child  abuse  PBC  BPA  toxin  public  health  public  safety  prevention  animal  fat  animal  protein  Leaky  gut  sick  population  health  crisis  agriculture  livestock  farming  livestock  Industrial  Industrial  Meat  Production  agriculture  DDE  diet-related  disease  chronic  disease  endocrine  disruptor  endocrine  system  autoimmune  disease  NHS  health  care  budget  health  care  cost  health  care  spending  toxic  waste  public  health  policy  public  health  risk  cancer  breast  cancer  WHO  cancer  growth  cancer  prevention  mutagenic  agents  mutation  DNA  damage  epigenetics  Standard  American  Diet  Western  pattern 
march 2016 by asterisk2a
Scientists get 'gene editing' go-ahead - BBC News
UK scientists have been given the go-ahead by the fertility regulator to genetically modify human embryos. It is the first time a country has considered the DNA-altering technique in embryos and approved it. The research will take place at the Francis Crick Institute in London and aims to provide a deeper understanding of the earliest moments of human life. It will be illegal for the scientists to implant the modified embryos into a woman. But the field is attracting controversy over concerns it is opening the door to designer - or GM - babies.
DNA  genes  geneticallyengineered  genetics  gene  editing  gene  expression  complexity  unknown  unkown  ethics  Religion 
february 2016 by asterisk2a
Video "Können wir Krebs besiegen?" | Dokumentation und Reportage | ARD Mediathek
[ POSITIONING, unlucky one to get cancer, now I have to fight this fight - "ich hab gekaempft, und ich hab gewonnen [...] "krieg im eigenen koerper." [...] das eigenen reperatur system schaft es nicht mehr mutierte zellen zu zerstoeren [...] min 14 - Prof Jeffrey Bluestone, immune therapy. people though about giving the immune system a kick in the butt. but he though about that the immune system regulates itself down to not to shoot over the target, and thus doesn't get rid of certain mutations. Immunotherapy results around 20%-50% success rate. [...] min 16 - 'Hufeland Klinik for holistic immunbiological therapy.' - Vegan, intravenous vitamins, etc. Spontaneous remission? [...] min 22 Vegan Diet! anti-inflammatory diet! Bad (animal products) diet can be as bad as smoking. Also research into unknown zoonotic disease (cows meat and milk) that are carcinogenic and can be transmitted through eating those animal products. &Vegan positive 4 epigenetics & intermittent fasting during chemo
cancer  diet-related  disease  chronic  diseases  immune  system  autoimmune  disease  chronic  low-grade  inflammation  inflammation  western  lifestyle  pharmaceutical  industry  pharma  big  pharma  Immunotherapy  anti-inflammatory  diet  Whole-Food  Plant-Based  obesity  tobacco  Vegan  medical  research  medical  care  medical-industrial  complex  medical  advances  Dean  Ornish  epigenetics  gene  expression  angiogenesis  DNA  fasting  intermittent  fasting 
january 2016 by asterisk2a
Overview - Sepsis - Mayo Clinic
More people die of Sepsis (in UK) than from all major forms of cancer (breast, bowel and prostate cancer combined) ~37.000. // In sepsis, the body's immune system goes into overdrive // Is a damaged information system ( of the immune system ) linked to higher cases of sepsis? like MS, autoimmune disease. // [S]lurred speech or confusion, [E]xtreme shivering, [P]assing no urine in a day, [S]evere breathlessness, "[I] feel like I might die.", [S]kin rash or mottled skin. SEPSIS // bit.ly/1JssTiy & wb.md/1lmai4m - deadly rush, out of control case of inflammation spreads across the body. Short-circuit. // Why is still unknown! //&! www.niams.nih.gov/Health_Info/Autoimmune/
inflammation  chronic  low-grade  inflammation  anti-inflammatory  diet  immune  system  autoimmune  disease  autoimmune  response  DNA  gene  expression  telomere  epigenetics  DNA  damage  Leaky  gut  Standard  American  diet-related  disease  Western  pattern  diet  diet  lifestyle  antioxidant  free  radicals  public  health  policy  public  health  cancer  heart  disease  sepsis  septicaemia 
january 2016 by asterisk2a
Future of human gene editing to be decided at landmark summit | Science | The Guardian
Jennifer Doudna, an inventor of a gene editing tool called Crispr-Cas9, said Asilomar was much in mind when the summit was organised. “I think it’s this generation’s version of Asilomar,” she says. “It’s a very exciting time, but as with any powerful technology, there is always the risk that something will be done either intentionally or unintentionally that somehow has ill effects.”
DNA  genetics  gene  doping  humanity  ethics  gene  editing  medical  profession  medical  advances  medical  research  GMO  evolution  complexity  unknown  unkown  unintended  consequences 
november 2015 by asterisk2a
Recorded Webinar: The Dietary Treatment of Cancer - YouTube
High-fat high-protein diets promote cancer. even vegetable fats. and both together is great environment for tumors. // thus 80/10/10 started by Doug Graham. and supported by T Collin Campbell in Whole to focus 80/10/10 macros in a Whole-Food Plant-Based Diet. // But Dr Greger also showed / talked about one study in his nutritionfacts.org videos, that even people threatened with death, are unlikely to change their diet, even if recommended by their treating physician. It's a case by case. Patient Compliance. WHY? Because people grew und and still live in an environment that is rigged against their health.
cancer  Whole  Plant  Foods  Whole-Food  Plant-Based  Diet  Vegan  Standard  American  Diet  alkaline  Western  pattern  anti-inflammatory  Dietary  Fiber  chronic  low-grade  inflammation  chronic  diseases  chronic  stress  IGF-1  insulin  endocrine  system  endocrinology  animal  protein  anabolic  steroid  DNA  telomere  animal  fat  free  oil  Palm  pharmaceutical  industry  pharma  big  pharma  medical  profession  medical  advances  medical  care 
october 2015 by asterisk2a
Chemistry Nobel: Lindahl, Modrich and Sancar win for DNA repair - BBC News
Their work uncovered the mechanisms used by cells to repair damaged DNA - a fundamental process in living cells and important in cancer. [...] DNA is open to an onslaught of different phenomena that can generate defects in our genomes. UV radiation and molecules known as free radicals can cause damage. Furthermore, defects can arise when DNA is copied during cell division - a process that occurs millions of times each day in our bodies. "Cigarette smoke contains small reactive chemicals, which bind to the DNA and prevent it from being replicated properly - so they are mutagens. And once there is damage in the DNA this can cause diseases including cancer," said Prof Lindahl.
inflammation  anti-inflammatory  diet  chronic  low-grade  inflammation  DNA  telomere  premature  ageing  cancer  ageing  anti-ageing  Oxidative  stress  antioxidant  chronic  stress  tobacco  Big  Sugar  Carnism  omnivore  Whole-Food  Plant-Based  Whole  Plant  Foods  Vegan  Standard  American  alkaline  diet  Western  pattern  diet  diet  animal  protein 
october 2015 by asterisk2a
Age of menopause 'controllers' found - BBC News
Damage corrected. Comparing the DNA of nearly 70,000 women allowed the researchers to identify the differences between those starting the menopause early and late. The team at Exeter and Cambridge universities showed that at least two repair mechanisms were involved. The first is used when the eggs are being formed and the woman's DNA is being broken, rearranged and repaired. The second corrects damage, caused by factors such as smoking or alcohol, throughout a woman's life. Both would influence the number of viable eggs a woman has. //&! Whole-Food Plant-Based Diet repairs DNA and telomere shorten slower. It is an anti-ageing diet. Period. - nutritionfacts.org/?s=DNA
telomere  DNA  epigenetics  genetics  premature  ageing  ageing  anti-ageing  Whole-Food  Plant-Based  Diet  carnism  omnivore  Standard  American  Diet  anti-inflammatory  inflammation  chronic  low-grade  inflammation  Western  pattern  dieting  sedentary  lifestyle  lifestyle  lifestyle  medicine  active  lifestyle  medical  profession  medical  research  medical  advances  genome 
september 2015 by asterisk2a
Old before your time? People age at wildly different rates, study confirms | Science | The Guardian
“Already, before midlife, individuals who were ageing more rapidly were less physically able, showed cognitive decline and brain ageing, self-reported worse health, and looked older,” the scientists write. // &! nutritionfacts.org/?s=ageing ie one evidence, whole plant food diet (vegan, no processed foods) mimics caloric restriction, thus lowers speed/progress of aging processes. and animal protein does increase it, as well as processed fast and junk food (mix of fats, sugars, processed carbs without fiber) which hits the insulin pump hard. and evidence has shown that pancreas has limited amount of cells to produce insulin - once they gone, age related diabetes is here; nutritionfacts.org/video/what-causes-diabetes/ // &! PREMATURE AGING does add substantially to rising health care cost to the already established demographic bubble factor.
epigenetics  premature  ageing  anti-ageing  ageing  complexity  unknown  unkown  chronic  stress  stress  Oxidative  stress  antioxidant  Standard  American  Diet  western  pattern  anti-inflammatory  alkaline  Vegan  omnivore  public  health  public  health  policy  health  crisis  sick  population  chronic  diseases  sedentary  lifestyle  western  lifestyle  active  lifestyle  lifestyle  medicine  DNA  telomere  fasting  intermittent  fasting  caloric  restriction  insulin  resistance  diabetes  obesity  epidemic  obesity  overweight  medical  profession  medical  advances  medical  research  demographic  bubble  health  science  well  being  noise  pollution  air  pollution  light  pollution  pollution  toxin  animal  protein 
july 2015 by asterisk2a
An Unstoppable Killer: New Research Suggests Cancer Can't Be Eradicated : NPR
The sensationalist assertions made in this article (particularly in the headline) don't follow from the results that the article describes. Part of the blame for this sensationalism seems to fall at the feet of the original scientist himself (Bosch). He makes an unfounded leap from the biological result that cancer seems to be an intrinsic property of genetic processes in cells (and the statements "You have to interfere with fundamental pathways", "It's a web of interactions" and "It's very difficult to do") to the assertion "will probably never be completely eradicated". Difficult is not the same as impossible. ||>> how we eat, how active we are, and our living environment (pollution and stress) is itself a multiplying factor whether or not we die of old age or of cancer or bc of complications of toxic medical cancer treatment. Period. Putting genetics out for the picture here. // via https://news.ycombinator.com/item?id=8210560
cancer  medical  research  medical  advances  medical  profession  Vegan  omnivore  pollution  chronic  stress  Oxidative  stress  stress  living  environment  well  being  living  standard  standard  of  living  public  health  public  health  policy  low-hanging  fruit  epigenetics  genetics  immune  system  antioxidant  free  radicals  radiation  cellphone  radiation  mutation  DNA  evolution  premature  ageing  anti-ageing  ageing  Transhumanism 
august 2014 by asterisk2a
BRCA Breast Cancer Genes and Soy - YouTube
turning on suppression mechanisms of cancer cell proliferation. and DNA repair ... called epigenetics. through ... Vegan Diet!
methylation  hypermethylation  BRCA-2  BRCA-1  Vegan  mRNA  genetics  breast  cancer  polymorphism  BRCA  RNA  epigenetics  DNA  cancer 
october 2013 by asterisk2a
BBC News - Milestone study probes cancer origin
The well-known ones such as UV damage and smoking mutate the DNA, increasing the odds of cancer.
Alcohol  immune  system  mutation  public  health  policy  pollution  western  lifestyle  ageing  genetics  vegan  environment  epigenetics  Oxidative  stress  smoking  lifestyle  skin  cancer  DNA  living  environment  premature  ageing  cancer  public  health  aging 
august 2013 by asterisk2a
Seeking Clues to a Heart Killer in the DNA Binding a Family - NYTimes.com
Researchers have long known that a family history of early death from heart disease doubles a person’s risk independently of any other factors. Family history is defined as having a father or a brother who were given a diagnosis of heart disease before age 55 or a mother or sister before age 65.
genetics  heart  disease  epigenetics  DNA  Cardiovascular  disease 
may 2013 by asterisk2a
Wie sich Fett auf den Stoffwechsel und die Gene auswirkt - SPIEGEL ONLINE
Fett zaubert nicht nur Polster auf die Hüften, es verändert auch Gene und Stoffwechsel. Forscher haben jetzt im Detail beobachtet, wie sich eine fettreiche Ernährung auf den Körper auswirkt. Demnach erhöht der Energieträger nicht nur Blutdruck und Hunger, sondern schraubt auch am Tag-Nacht-Rhythmus. >> Low-Fat (No Oil) Vegan Diet <<
body  fat  adipose  tissue  leptin  immune  system  diabetes  autoimmune  disease  obesity  public  health  policy  obesity  epidemic  sleeping  adipocytes  health  crisis  melatonin  epigenetics  endocrine  system  chronic  low-grade  inflammation  REM  sleep  inflammation  autoimmune  response  blood  pressure  metabolism  endocrine  disorders  sleep  Cardiovascular  disease  genetics  vegan  hygiene  metabolic  syndrome  DNA  gene  expression  endocrinology  public  health 
may 2013 by asterisk2a
Exercise Can Be Good For The Heart, And Maybe For Sperm, Too : Shots - Health News : NPR
A study finds that guys who watched a lot of TV had lower sperm counts than more active fellows. The effect held true even when other factors, such as body weight and diet, were taken into account. Sedentary Lifestyle affects epigenetic. Switching certain genes off. Like a Change of diet from unhealthy to healthy (ie vegan) switches lots of genes on that fight chronic diseases and cancer.
lifehacker  vegan  epigenetics  medical  advances  DNA  lifehacks  exercise  western  lifestyle  gene  expression  medical  research  western  diet 
february 2013 by asterisk2a
The Optimal Diet - NYTimes.com
Dr. Dean Ornish op ed in the New York Times warns about dangers of low carb diets (http://nyti.ms/Pdkpei). I wrote a whole book about it, now online free at:

http://www.atkinsexposed.org/

Perhaps the biggest misconception is that as long as you lose weight, it doesn’t matter what you eat. But it does. Yet being thin and being healthy are not at all the same thing. Being overweight is not necessarily linked with disease or premature death. What you eat affects which diseases you may develop, regardless of whether you’re thin or fat. Some diets that may help you lose weight may be harmful to your health over time.

Vegan Diet + Regular Exercise + Stress Management = risisng probability of Good Health into old age (dying of age, not bc of a disease).

WHAT you eat is as important as what you exclude.
Book  Dean  Ornish  healthcare  health  crisis  Cardiovascular  disease  chronic  diseases  Amphetamines  metabolism  metabolic  rate  chromosome  DNA  telomere  epigenetics  diabetes  prostate  cancer  cancer  inflammation  stress-management  stress  Exercise  overweight  obesity  obesity  epidemic  coronary  artery  disease  coro  heart  disease  health  health  science  nutrition  diet  Atkins 
september 2012 by asterisk2a
Why Fathers Really Matter - NYTimes.com
Doctors have been telling men for years that smoking, drinking and recreational drugs can lower the quality of their sperm. What doctors should probably add is that the health of unborn children can be affected by what and how much men eat; the toxins they absorb; the traumas they endure; their poverty or powerlessness; and their age at the time of conception. In other words, what a man needs to know is that his life experience leaves biological traces on his children. Even more astonishingly, those children may pass those traces along to their children.

[...] Genes matter, and culture matters, and how fathers behave matters, too.

**A certain lifestyle and environment switches on/off certain genes and functions - point in time information - that gets carried on to the baby.**

[...] Our genes can be switched on or off by three environmental factors, among other things: what we ingest (food, drink, air, toxins); what we experience (stress, trauma); and how long we live.
psychology  environment  pollution  diet  nutrition  health  science  evolution  childhood  development  lifestyle  DNA  epigenetics  genetics  gene  parenthood  parents  parenting  medical  advances  medical  research 
september 2012 by asterisk2a
Popeye had the right idea as favourite snack spinach could cut colon cancer | Mail Online
Researchers at Oregon State University found eating the green leafy vegetable reduced the damaging effects of a carcinogen found in cooked meat.
They were studying the complex biological effects of the cancer-causing substance on microRNA and cancer stem cells.
During their animal study they found that the consumption of spinach could partially offset the damaging effects of the carcinogen. In tests with laboratory animals, it cut the incidence of colon tumors almost in half, from 58 per cent to 32 per cent.
'Cancer development is a complex, multi-step process, with damaged cells arising through various means,'

increasing interest in the role played by epigenetics, in which such factors as diet, environmental toxins, and lifestyle affect the expression of genes – not just in cancer, but also cardiovascular disease, diabetes, and neurological disorders.
genetics  DNA  epigenetics  spinach  vegan  health  diet  cancer 
june 2012 by asterisk2a
A Sushi Secret Uncovered in L.A.
Mislabelling of seafood's origin via DNA testing.
DNA  FDA  Food  Industry 
april 2012 by asterisk2a
Cancer and epigenetics: Cancer’s epicentre | The Economist
Cancer ...
Sometimes the genetic flaw is inherited. Sometimes it is the result of exposure to an outside agent such as tobacco smoke or radioactivity. Sometimes it is plain bad luck; a miscopying of a piece of DNA during the normal process of cell division.

No one has worked out how to repair DNA directly. It is, rather, a question of discovering the biochemical consequences of the genetic damage and trying to deal with those instead. But recently, another pattern has emerged. It is too early to call it a breakthrough as significant as the cancer-is-caused-by-broken-genes finding, but it might be.

Epigenetics, switches genes on and off by plastering either their DNA or the proteins which support that DNA in chromosomes with clusters of atoms called methyl and acetyl groups.

Epigenetic processes are susceptible to chemical intervention in a way that genetic mutations are not.

Epigenetics might justly take its place alongside genetics in the analysis and treatment of cancer.
DNA  cancer  epigenetics  genetics 
april 2012 by asterisk2a
DNA robot kills cancer cells : Nature News & Comment
“We call it a nanorobot because it is capable of some robotic tasks,” says Ido Bachelet, a postdoctoral fellow at Harvard Medical School in Boston, Massachusetts, and one of the authors of the study, which is published in this week’s issue of Science1. Once the device recognizes a cell, he explains, it automatically changes its shape and delivers its cargo.
medical  advances  DNA  cancer 
february 2012 by asterisk2a
Technology Overview | Halcyon Molecular
Company trying to read full DNA (30 bn bases). Not just 200 bases.
DNA 
february 2012 by asterisk2a
Cancer research: Take five | The Economist
technology and its exponential growth leads to advances in cancer research and possible treatments ...
technology  genome  research  DNA  cancer 
january 2012 by asterisk2a
Gehemmtes Algenwachstum: Nano-Müll stört Leben im Wasser - SPIEGEL ONLINE - Nachrichten - Wissenschaft
"Nanopartikel werden noch viel schwieriger aus der Umwelt zu entfernen sein als Chemikalien. Sie sollten deshalb idealerweise erst gar nicht dort hineingelangen."
ecosystem  nano  nanotechnology  complexity  algae  unintended  consequences  nanoparticle  DNA  damage 
november 2011 by asterisk2a

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