asterisk2a + a   38

Bisphenol A bleibt "besonders besorgniserregend" - Entscheidung des EuG - SPIEGEL ONLINE
Die umstrittene Chemikalie Bisphenol A wird in der EU weiterhin als gefährlich eingestuft, hat das Europäische Gericht entschieden. Ein Branchenverband hatte gegen die Bewertung geklagt.
BPA  Bisphenol  A 
july 2019 by asterisk2a
'BPA-free' plastic accelerates embryonic development, disrupts reproductive system in zebrafish : science
Yeah. You know why? Because we replaced BPA with another plasticizing compound that does the exact same thing. BPS, the BPA replacement chemical, is structurally very similar to BPA and, therefore, we shouldn't be shocked when it exerts a similar impact on the reproductive system. Because we need the plasticizers to serve a particular function in the production of plastics, they are relegated to a fairly particular type of chemical structure. This means there all pretty likely to look the same and act the same. That is, as weak estrogens.
BPA  bisphenola  Bisphenol  A  endocrine  disorders  endocrine  system  endocrinology  plastic  nation  Consumer  Protection  public  health  policy  public  health  public  safety  Petroleum  Industry 
february 2016 by asterisk2a
The Chemical in Cupcake Wrappers and Cookware Might Be Causing Cancer | Mother Jones
C8 is in a chemical family called PFCs (perfluorinated chemicals)—the same water- and stain-proofing class of chemicals used to make rain gear, pizza box and popcorn bag liners, stainproof upholstery treatments, and those waxy slips that hold pastries at cafes. Dozens of studies have linked PFCs to all sorts of health problems, from kidney and testicular cancer to increased risk of miscarriages. (3M phased out the chemical from production in 2002 due to potential health hazards.) [...] PFC contamination may not be isolated to the Ohio Valley. According to an Environmental Working Group (EWG) report that uses recent EPA data, C8 has been found in the drinking water in 94 counties serving more than 6 million Americans. (An interactive version of this map is available here.) [...] The EPA is in the process of investigating C8's health effects; in the meantime, it has set voluntary C8 safety standards to be used by utility companies. [...] avoid nonstick, stainproof, or waterproof items
carcinogen  carcinogenic  Teflon  chemicals  public  health  policy  public  health  self-regulation  regulation  regulators  Wall  Street  profit  maximisation  shareholder  value  cancer  endocrine  disorders  endocrine  system  BPA  DDT  PFC  Agent  Orange  bisphenola  Bisphenol  A  Chemical  Industry  capitalism  Asbestos  water  pollution  pollution  ecological  disaster  environmental  disaster  Consumer  Protection  zombie  revolving  door  USA  public  awareness  public  perception  Petroleum  Industry 
october 2015 by asterisk2a
Pando: The most patient man in Silicon Valley
Too much in Silicon Valley revolves around hyperspeed. Everything in the startup world is an emergency that needs to be solved in an all-nighter last night, if you allow it to be. The genius in Ravikant’s AngelList is its measured, methodical, brick-by-brick pace to build a software platform to replace, save, wreck, or augment – the verb depends on your point of view – a business that everyone insisted for decades was incurably human, boutique and done with deeply-trusted partnerships and eye-to-eye handshake deals. //&! bit.ly/1LS4aVg - The “The old Series A investor who put in $2 million and really cared and had resources is dead.” [...] “A seed fund doesn’t have the resources that a Kleiner Perkins or a Benchmark had,” [ Incubators are only 3 months long ] AngelList syndicate leads help, but they don’t care enough to help [as classic VC's] [...] Entrepreneurs have to stitch it together themselves.”
Naval  Ravikant  AngelList  Venture  Capital  Silicon  Valley  Networking  Software  Is  Eating  The  World  crowd  funding  Seed  Round  Angel  Investor  disruption  disrupting  markets  bottom  up  SPV  growth  Party  Round  Angel  List  angel-list  A  Round  Start-Up  lesson  Start-Up  advice 
october 2015 by asterisk2a
Pando: Good news! B rounds have doubled in value over five years!
B Round! doubling down on (to a certain point) proven ideas as they move to make themselves solid/viable (building business model & continued growth if not even putting some more gasoline on the fire with a B Round - allocation of resources). thus there is competition thus bidding up in a private market. BUT BUT also reflects the rising cost! Rising cost to grow, the war for talent to scale, and the cost in said hubs/ecosystems where the talent are already working on scaling other companies, where rent is sky high and space rare to expand office, ops, ramp up head count, ... // why, on a side note!, ? because global ZIRP, NIRP, QE, hunt for yield, FOMO, property speculation, alternative asset management and allocation (newly minted paper millionaers) have bid up prices in metropolitan and hot cities by credit bubbles around the world. bc financial markets are global, thus your allocation/diversification is global, not limited where ur home addr is. adding to volatiliy too bc of froth!
Silicon  Valley  Seed  Round  Party  Round  SPV  Venture  Capital  Private  Market  FOMO  hunt  for  yield  B  Round  A  Round  growth  Private  Equity  Hedge  Fund  Angel  Investor  Micro  VC  2015  cost  of  living  credit  bubble  cost  of  entry  aspirational  leverage  margin  trading  asset  bubble  asset  allocation  distortion  ZIRP  NIRP  QE  BOE  BOJ  Abenomics  PBOC  Fed  unintended  consequences  burn  rate  runway  ECB  Mutual  Fund  unknown  unkown  inflation  targeting  Fed  mandate  inflation  expectation  secular  stagnation  deflationary  deflation  economic  growth  speculative  bubbles  speculative  speculation  reflate  reflation  monetary  policy  unconventional  monetary  policy  financial  financial  repression  western  world  Developing  BRIC  emerging  complexity  incomplete  information 
september 2015 by asterisk2a
Pando: In the Valley, pre-seed is a meme. In New York, it’s a necessity
// cost of entry? // unable to make it happen? // Can't you write software from anywhere? // problem, heavily diluted early on approaching A/B, traditional shops don't like the cap table of pre-seed, angels, seed, accelerator & Micro VC's already owning ~+40% ... you come to a traditional A/B shop and not one of the existing investors is actually leading the round or committed in paper do double down? // // from a financial perspective/investment/math --- in the PRIVATE MARKET thrown under the bus by NIRP, QE, hunt for yield and FOMO (looking for their female unicorn or own Zuck) everyone can run 100 burger stands with unlimited/stellar returns in their spreadsheet model (bc cost of capital being 0 or negative). Despite the deflation of price of software & hosting (marginal cost, economics of abundance), Talent got bid up heavily (+200k/y in LA by Snapchat) in certain cities (SV, NY, London) // &! Steen Jakobsen - youtu.be/fnp5ETnKylU - min 16 avg guy does not have access to credit!
Seed  Round  Party  Round  Venture  Capital  Micro  VC  barriers  to  entry  cost  of  entry  London  Start-up  Scene  ecosystem  New  York  Scene  burn  rate  runway  traction  A  Round  seedfunding  funding  Angel  Investor  dilution  cap  table  lesson  advice  liquidation  preferences  hunt  for  yield  2015  distortion  FOMO  equity  bubble  credit  bubble  ZIRP  NIRP  QE  asset  allocation  Limited  Partners  monetary  policy  fiscal  policy  Wall  Street  asset  bubble  behavioral  finance  behavioral  economics  Silicon  Valley  Private  Market  Public  Market  reflate  reflation  cost  of  living  valuation  Unicorn  Decacorn  cost  of  leverage  financial  repression  financial  literacy  financial  financial  cycle  business  cycle  business  confidence  consumer  confidence  hubris  panic  irrational  exuberance  retail  banking  investment  banking  fractional  reserve  banking  banking  crisis 
september 2015 by asterisk2a
Y Combinator Finally Reveals Its Approach To Growth-Stage Investing | TechCrunch
- signaling risk - do or not do follow-on round participation, but exists with every existing investor (on the bend to invest in next round or not and have pro rata) http://www.bothsidesofthetable.com/2010/04/03/understanding-vc-signaling/
ycombinator  growth  round  signaling  risk  Venture  Capital  Seed  A 
july 2015 by asterisk2a
#TOA14 Interview with Julie Meyer (CEO & Founder, Ariadne Capital) - YouTube
(1) why not to go to Palo Alto (2) money will find you if you are good enough/traction. // &! Enterprise Connect Presents: Raising Finance; Top Tips From Industry Experts (Highlights) - youtu.be/9Psgw5oJSMs // &! Lecture 9 How to Raise Money Marc Andreessen, Ron Conway, Parker Conrad - youtu.be/NJAKt1icZYs
Start-Up  lesson  Start-Up  advice  traction  Focus  Product/Market  Fit  MVP  Minimal  Viable  Product  viral  coefficient  Net  Promoter  Score  network  effect  Venture  Capital  hunt  for  yield  Seed  Round  A  Round  Angel  Investor  London  Scene  Berlin  Start-Up  Scene  Networking 
july 2015 by asterisk2a
Fear Trumps Greed in Silicon Valley as Some Venture Firms Hedge - Bloomberg Business
[... high ops cost associated w SF/Palo Alto ... fancy office (and expensive (rarefied) developers from Google or Facebook) in SF as a sign of success while burning +2m per year at least with no cash flow in sight ... and with all consumer products being free and hoping to finance themselves in the future with advertising ... ] Some VCs are urging their companies to build a rainy day fund to ensure their survival. [...] It’s a constant battle deciding whether to invest in a potentially lucrative deal, said Philadelphia financier Rudy Karsan: “Greed versus fear.” [ Softbank Capital just last week came out publicly with a shift in strategy, to invest now ONLY in proven winners, at slightly premium to get in (and with preferred liquidation preferences in writing), &focus resources on those portfolio companies ... than to compete in a crowded, distorted, muggy, in transparent, very speculative (with lots of ifs and luck and bet on CEO to execute well) A-, B- (and C-Round) market. ]
Silicon  Valley  burn  rate  runway  cash  flow  cash-is-king  hunt  for  yield  distortion  ZIRP  NIRP  QE  growth  round  SPV  war  for  talent  Private  Market  Private  Equity  Hedge  Fund  Mutual  Fund  bubble  USA  Fed  Taper  asset  bubble  asset  allocation  Angel  Investor  Seed  business  model  advertising  VC  Venture  Capital  Greed  FOMO  bubble  speculative  bubbles  speculative  speculation  SoftBank  Capital  IPO  NASDAQ  A  Unicorn  Decacorn  termsheet  liquidation  preferences  exit  strategy  M&A  acquisition  acquihire  acqui-hire  business  cycle  business  plan  business  investment  business  confidence  consumer  confidence  leverage  debtoverhang  irrational  exuberance 
july 2015 by asterisk2a
The frustrating, no-win "Goldilocks Zone" of seed deals
Don’t do party rounds. Raise as much as you possibly can so you don’t get crunched. Don’t raise money from just seed funds. Don’t raise money from just big name VCs unless you know you’ll breakthrough, and then absolutely do. And actually you never know that, so nevermind. Oh, and good luck rationalizing all of this advice, first timers. [...] TL;DR version: Large VC firms may do lots of seed deals but each partner will only do one to two Series A deals a year. So basic math tells you it’s a game of survivor. Most of the seed deals will not get a Series A from that firm. The concern is if you don’t quite make the cut, is the signal so bad to other VCs that you are worse off than if you never raised that, say, $200k from a big name VC to begin with? [ not every product consumer or b2b will not be a 500m/1bn dollar company, thus it's not worth it to raise risk capital and just grind it out!? at a sustainable pace, putting back in what you earned. ] &! bit.ly/1HjO13v
Seed  Round  Party  Round  Start-Up  lesson  Start-Up  advice  Angel  Investor  Micro  VC  Venture  Capital  Series  A  seedround  seedfunding  traction  business  model  Silicon  Valley  economies  of  scale  pageviews  Unicorn  valuation  speculative  bubbles  speculative  speculation 
july 2015 by asterisk2a
You Need To Be A Billion Just To Make A Million | TechCrunch
[ especially consumer apps being hit driven business, already, that can go out of fashion as quickly as they came, might be a flash in a pan like Secret & work only on the SV/SF ] Competition in the Valley has started reaching a new peak, with candidates demanding all kinds of accoutrements just to change jobs. But it’s not just recruiting that has become more challenging. Sales, marketing, public relations — essentially every task that a startup has to do is just more difficult today given this cutthroat environment. The only way to respond to the higher threshold has been to raise ever more capital, and earlier as well. We now have the rise of the “instant unicorn” that can raise hundreds of millions of capital in just the first months of a company’s existence. That means companies are already worth billions, before they may have made their first million dollars in revenue or gotten their first million users. That’s the new normal, and founders have to be ready to adapt.
Silicon  Valley  San  Francisco  barriers  to  entry  distortion  NIRP  ZIRP  QE  A  Round  Seed  Round  Angel  Investor  hunt  for  yield  Private  Market  competitive  advantage  ecosystem  burn  rate  runway  MVP  Product/Market  Fit  Start-Up  lesson  Start-Up  advice  unintended  consequences  bubble  speculative  bubbles  speculative  speculation  Venture  Capital  Private  Equity  growth  growth  hacking  growth  hacker  structural  imbalance  Impediments  creative  destruction  Unicorn  competitiveness  competition  competitive  Signal  vs.  Noise  allocation  attention  span  New  York  Start-Up  Scene  Silicon  Alley  HR  human  resources 
may 2015 by asterisk2a
New stats show raising Seed money from big VCs increases survival. (The opposite of what everyone in the Valley says) | PandoDaily
(2) Don’t do a “party round” (2) Don’t raise money from a major VC. They will only follow on with the best companies and the signaling risk if they say no can be damning. [...] The companies who raised funds from large VC firms did better than those who raised funds from micro-VCs. [...] The anecdotal stuff is true & the data is true. The answer to how thats possible lies, as everything else in venture world does, with a massive range of quality & low barriers to get in. [...] the # of firms who invest at least $1 million a quarter 4 at least four straight quarters, there are only a paltry 97 firms left in the industry. [...] Raising big institutional funds is hard. Even shitty big VC firms have 2 meet some kind of bar 2 get that money — which is increasingly disappearing in the US. [...] [ hypothesis/thesis of micro-VC is flawed & opportunistic of lower Start-up cost 2 get from idea 2 MVP 2 Product/Market Fit with some traction. higher delta between good & bad co&mVC&angel ]
Start-Up  lesson  Start-Up  advice  Venture  Capital  Seed  Round  Angel  Investor  Party  Round  distortion  hunt  for  yield  economic  history  unintended  consequences  ZIRP  NIRP  QE  technological  history  technological  progress  Micro-VC  VC  Product/Market  Fit  post-traction  Series  A  MVP  meritocracy  meritocratic  Accelerator  ycombinator  Seed  Camp  TechStars  500  Start-ups 
april 2015 by asterisk2a
(Founder Stories) Instagram-Backer Steve Anderson: Forget The Billion-Dollar Exits | TechCrunch
“the reality also was on Sand Hill Road everyone talks about the billion-dollar exits, and if you look at the history of the last 15 years, there has not been that many billion dollar exits … it turns out that the average exit over the last 10 years on average has been $100-million, and so I was thinking to myself well if I owned 10% of a $100-million outcome that is real money for me, and my co-founders and anybody else and so why isn’t there anybody whose capital was aligned and incented for that outcome?” // A Round is post-traction round. Decision has to be made whether to invest (A Round), dilute yourself, drive burn rate up acquiring more customers than normal rate vs cash flow positive Start-up that grows organically with rising revenues and staying cash flow positive. Fork in the road can be a credit line from VC. // VC's have to bet & have 2 invest 2 return the fund & more. Sometimes its not in the interest of the founder & company economics that got only ~<250m exit horizon.
Seed  Round  Angel  Investor  A  Round  Start-Up  lesson  Start-Up  advice  Venture  Capital  2011  Silicon  Valley 
april 2015 by asterisk2a
[PreMoney MIAMI] Upfront Ventures, Mark Suster, "Venture Outlook 2015 - Goldrush or Fool's Gold" - YouTube
(1) Change from Sales Funnel to Funnel of Intent on Mobile and Social Media. Lower Marketing/Early user acquisition cost at scale. And tap to credit cards to with one click through third party Platforms. And also Open Source Software Stacks and buying 'by time' the hardware stack on Google, AWS or Azure is paradigm shift. Results also in noise one has to break through first - raising the bar (by user choice) for everyone. (2) min10 - Value Creation held inside Private Market through growth & late-stage investing instead of IPO with single-class share structure with wobbily business numbers 'help you god that you aren't out 24m later' because of impatient Wall Street. (3) min14 Series D valuations show Private Market highest bidder wins phenomenon. But Valuations are up across the board. And with more Seed/Angel Investors, Seed Valuations are also bid up higher compared to ABC. // &! min29 youtu.be/25TxrhsXFvs - 500 Startups, Dave McClure "4 Years of Moneyball - What Have We Learned"
Silicon  Valley  Seed  Round  A  Round  growth  Venture  Capital  Sales  Funnel  Funnel  of  Intent  mobile  first  mobile  homescreen  mobile  phone  Social  Media  Start-Up  lesson  Start-Up  advice  hunt  for  yield  ZIRP  NIRP  QE  secular  stagnation  productive  investment  Private  Market  Platform  TOS  2000  dot.com  bubble  2008  IPO  Wall  Street  single-class  share  structure  SPV  short-term  thinking  short-term  view  Hedge  Fund  Mutual  Fund  Private  Equity  late-stage  funding  Unicorn  seedround  seedfunding  angelinvestor  angel-list  Angel  Investor  angelinvestors  incomplete  information  complexity  unintended  consequences  Dave  McClure  Mark  Suster  UpFront  Ventures  500  Start-ups  paradigm  shift 
april 2015 by asterisk2a
Mike Judge Explains Silicon Valley’s Success and Offers Hints About Season 2 - YouTube
min 15 - ideas on the fringe (looking crazy at the start and get ridiculed), and succeed, happen in the Valley. Everyone else can do the ideas that are not on the fringe. But every ideas VCs get pitched are fringe in general. SV = be on the fringe, work at the fringe, live on the fringe. When they work, they tend to work really really well. || Fear of Bubble & Hype Cycle >> Reduce risk, don't get sloppy. || end - "Start-up life is struggle." but public perception is like the lego movie everyone is singing 'everything is awesome' and dancing ...
Start-Up  lesson  Silicon  Valley  Start-Up  advice  Venture  Capital  Seed  Round  A  Round  creative  destruction 
april 2015 by asterisk2a
Gillmor Gang: Money for Nothing - Gillmor Gang | TechCrunch TV
min 42 // A Round is now a "post-traction" investment aka proven product & business model. A Round is an investment to scale it up, put it up a bunch of gears. // Keith Teare from chat.center (tcrn.ch/1IWFQ1X) people now doing pre-seed, seed, seed prime & bridge funding via existing investors; figuring out Product/Market fit, traction, funnel, etc. Now more than ever a hits driven business. // see also tcrn.ch/1c54UpN // Complexity of phenomenon - symptoms, causes and tangents; biases, selection bias, pattern matching, bidding up hot deals in the private market where the highest bidder will get the deal - irrationality of accepting those valuations and the founders Unicorn-status need, hunt for yield, trendy - the future, when doing 'hard things' becomes fashionable (ie Reality TV, TV Series & a shallow Channel 4's How To Be A Young Billionaire) then beware, negative yields for secure investments (bonds and corp debt), perceived 'conservative' value vs private bid up bubble potential.
Seed  Round  A  Round  traction  hunt  for  yield  ZIRP  NIRP  QE  unintended  consequences  Silicon  Valley  asset  bubble  asset  allocation  behavioral  finance  bond  bubble  bubbles  equity  bubble  demographic  bubble  secular  stagnation  complexity  growth  Start-Up  lesson  Start-Up  advice  pattern  matching  selection  bias  confirmation  bias  bias  Unicorn  Wall  Street  Private  Mutual  Fund  Hedge  Fund  Venture  Capital  savings  glut  productive  investment  business  model  Snapchat  WhatsApp  Instagram  Slack  Uber  productivity  output  gap  STEM  Share  Economy  Services  Industry  Niedriglohnsektor  incomplete  information  economic  history  marginal  cost  liquidity  trap  sovereign  debt  crisis  debt  bubble  zombie  banks  zombie  consumer  zombie  corporations  structural  imbalance  global  imbalances  faultlines  Product/Market  Fit  value  creation  1000  True  Fans  Core  Product  Proposition  differentiate  differentiation 
april 2015 by asterisk2a
The Potential Upside To A Technology Bubble | TechCrunch
just look at the graph, seed ang frowth round are impacted only. while a is still up a sizable 80% y/y. makes sense. // // From the article ""I am currently reading Antifragile. The premise of the book is looking at potential gains in times of disorder [R.I.P. Good Times Slide Show (2008) - http://tcrn.ch/ZBZw7u], and it’s a terrific read for those involved in startups and investing. Navigating fundamental shifts in technology and outer market forces are key characteristics of great founders. I look at the funding landscape and see a terrific environment for learning. Bubble or not there are certain things that remain true. Great founders create amazing companies and great founders will always find a way to succeed."" // 1bn valuation and the attribution of Unicorn and 'product CEO' for life of _your_ company, became a status symbol. // first lava stream of money bid-up asia and brick, now flown/flowing out and bidding up the Private Market where highest bidder wins.
Silicon  Valley  Seed  Round  growth  hunt  for  yield  A  Round  GFC  recession  Unicorn  symptom  burn  rate  superficial  status  anxiety  status  symbol  Private  Equity  bubble  bond  bubble  ZIRP  NIRP  QE  distortion  secular  stagnation  liquidity  trap  speculative  bubbles  Super  Rich  1%  asset  allocation  incomplete  information  complexity  herding  bubbles  demographic  bubble  asset  bubble  Structural  Impediments  imbalance  faultlines 
april 2015 by asterisk2a
What you label your funding round matters a lot less than how much you raise and what you accomplish | PandoDaily
It’s not inherently wrong to skip a Seed round altogether, or to raise a Seed so large that your next round effectively becomes a B round. But where the issue arises is in choosing such a path and not knowing you’re on it, and thus failing to deliver accordingly. Putting aside the occasional exceptions of outlier companies, proven repeat founders, and the like, there’s a predictable cadence to startup funding and the expectations that VCs set at each stage along the way. If you want to play the game, you have to know the rules.
Venture  Capital  Seed  Round  Series  A  Start-Up  lesson  Start-Up  advice  traction  growth 
april 2015 by asterisk2a
How I discovered a coffee pot was making my patient sick - Quartz
In January, a study published in PLOS linked environmental chemical exposure with early menopause. This study suggests a connection between the ubiquitous chemicals we’re exposed to and our health. Other studies support this concept, such as a 2014 research study showing BPA in the liners of canned beverages increases blood pressure. Health care providers generally are not taught to consider common household items as a potential cause of disease, but perhaps we should be. BPA is a known endocrine disruptor. Research evidence links BPA exposure with early puberty, infertility, breast cancer, and abnormal periods. It has also been tied to obesity, prostate cancer, and neurodevelopmental problems in children. The National Health and Nutrition Survey (NHANES) found that obese adults are likely to have higher levels of BPA in their urine. [...] And lest you think “BPA-free” is the answer, the substitute plastics which contain bisphenol S or other resins appear to be equally hazardous.
BPA  bisphenola  Bisphenol  A  plastic  nation  pesticide  herbicide  fungicide  ecological  disaster  environmental  disaster  Great  Pacific  Garbage  Patch 
april 2015 by asterisk2a
Why Jeff Clavier insists there’s no Series A Crunch | PandoDaily
It wasn’t that VCs were going to do fewer Series A deals than they have in the past. It was because there was a limit to how many more Series A deals the industry could do in a given year, since most VCs only do one to two deals per year. The explosion of incubators, angels, and seed funds meant there would be thousands more companies [ <100's with serious traction, seriously ] vying for those one or two yeses per partner per year. [...] [...] Clavier pushes his companies to raise ginormous seed rounds– way more than they think they want. He’ll routinely talk an entrepreneur who just wants to raise $750k into more than doubling that. Cynics could say this pushes an entrepreneur to give away more ownership at a higher early price and have less control, but the logic is that seeds are the only place where there’s a glut of money and you don’t have to prove a lot to get it. Load up while you can. That gives the company enough room that it can hit momentum .... & bit.ly/1ask6Np
Silicon  Valley  Venture  Capital  Start-Up  lesson  Start-Up  advice  Seed  Round  traction  execution  A  Round 
april 2015 by asterisk2a
Plastik - Die Geißel der Welt-Meere - YouTube
>> "Kinderspielmacher werden nie fuer Kinder [und deren Sicherheit und Gesundheit] hergestellt. Sondern um Geld zu machen fuer den Hersteller." & "Wir muessen uns vor unserer eigenen dummheit schuetzen." - Cradle to Cradle
Great  Pacific  Garbage  Patch  plastic  bag  plastic  nation  plastic  ecological  disaster  environmental  disaster  unintended  consequences  bisphenola  Bisphenol  A  BPA  Phthalate  Weichmacher  Petroleum  Industry  carcinogen  carcinogenic  lobby  Lobbying  lobbyist  Consumer  Protection  public  awareness  Policy  Makers  error  folly  Career  Politicians  consumerist  Consumerism  zombie  Polyethylene  public  health  public  health  complexity 
november 2014 by asterisk2a
Dortmund-Bayern: Pep Guardiola gewinnt Duell mit Klopp - SPIEGEL ONLINE
Münchens Trainer brachte Mario Götze für Mario Mandzukic und damit einen ballsicheren Offensivspieler, der sich von gegnerischem Pressing nicht beeindrucken lässt. Götze positionierte sich tiefer als Mandzukic und sorgte dadurch nicht nur für Überzahl im Zentrum, sondern erhöhte das spielerische Potential. Die Änderungen sollten sich auszahlen. [...] Diese und viele weitere kleinere Veränderungen Guardiolas brachten Bayern den Sieg. Das ist eine seiner größten Stärken: das Coaching während der 90 Minuten. Wie er auf Stärken des Gegners und Schwächen der eigenen Elf reagiert, ist außergewöhnlich. [...] http://www.spiegel.de/sport/fussball/dortmund-vs-bayern-muenchen-pep-guardiola-hat-juergen-klopp-ueberrascht-a-935327.html [...] Flexibilität ist das zentrale Motiv der Arbeit von Münchens Trainer Guardiola. [...] http://www.spiegel.de/sport/fussball/fussball-bundesliga-borussia-dortmund-verliert-gegen-bayern-muenchen-a-935304.html
Soccer  Bundesliga  Pep  Guardiola  Sport  Coaching  Reading  a  Game  Excellence  Jürgen  Klopp  flexibility  fcbayern  Bayern  Munich  FC  Bayern  München 
november 2013 by asterisk2a
▶ Michael Sandel: Why we shouldn't trust markets with our civic life - YouTube
n the past three decades, says Michael Sandel, the US has drifted from a market economy to a market society; it's fair to say that an American's experience of shared civic life depends on how much money they have. (Three key examples: access to education, access to justice, political influence.) In a talk and audience discussion, Sandel asks us to think honestly on this question: In our current democracy, is too much for sale?
market  economy  Career  Politicians  lobby  lobbyist  incentive  accountability  public  discourse  Gini-coefficient  Lobbying  values  affluent  Michael  Sandel  everything  is  up  for  sale  responsibility  short-term  thinking  philosophy  working  poor  social  science  happiness  civic  life  political  error  intrinsic  motivation  common  good  corruption  satisfaction  economics  life  lesson  faultlines  lifehacker  Society  putting  a  price  on  everything  justice  ethics  non-material  goods  public  policy  western  lifestyle  education  fairness  Law  &  capitalism  political  folly  private  healthcare  civil  democracy  healthcare  market  ordinary  life  moral  beliefs  book  financial  incentive  western  public  morals  inequality 
october 2013 by asterisk2a
BPA linked to errors in human egg development — Environmental Health News
A new study with human eggs shows that bisphenol A causes errors that can prevent eggs from developing fully and may contribute to infertility. The effects were found at the lowest dose tested, which was lower than levels that have been measured in women's ovaries. The findings are consistent with numerous animal studies. Machtinger, R, CMH Combelles, SA Missmer, KF Correia, P Williams, R Hauser and C Racowsky. 2013. Bisphenol-A and human oocyte maturation in vitro. Human Reproduction 28(8) http://dx.doi.org/10.1093/humrep/det312
Bisphenol  A  infertility  bisphenola  BPA 
august 2013 by asterisk2a
Vitamin A and systemic inflammation as protective factors in multiple sclerosis
New findings on multiple sclerosis: An above minimum vitamin A level in the 2nd of five quintiles is associated with a -62% reduced risk of developing multiple sclerosis. Moreover, higher hs-CRP levels (=greater inflammation) in the younger years offer protective effects as well (-64%).

Conclusions: Our results suggest that sub-optimal vitamin A levels may be associated with MS risk. The association between hs-CRP levels and MS risk in young subjects may support the role of the hygiene hypothesis in MS aetiology.

- hygiene hypothesis calls for breast feeding
- hygiene hypothesis calls for less over protective over less cleanliness environment for kids. let kid be kids. what can't kill them, doesn't kill them.

http://www.drweil.com/drw/u/ART02759/facts-about-vitamin-a
- Eat your vegetables and colourful fruits. Not pills. Food.

Years of chronic deficiency leads to chronic diseases.

http://nutritionfacts.org/index.php?s=multiple+sclerosis
parents  autoimmune  response  immune  system  Vitamin  A  autoimmune  disease  parenthood  hygiene  hypothesis  multiple  sclerosis  Vegan  parenting 
january 2013 by asterisk2a
Topical vitamin A treatment of recalcitrant common warts.
Topical vitamin A has been shown to be a successful treatment of common warts in prior informal studies.

Daily topical application of natural vitamin A derived from fish liver oil (25,000 IU) led to replacement of all the warts with normal skin. Most of the smaller warts had been replaced by 70 days. A large wart on the middle knuckle required 6 months of vitamin A treatment to resolve completely.
Warts  verruca  vulgaris  Vitamin  A  HPV  benign  lesions  cancerous  lesions  common  alternative  Medicine  Human  papillomavirus 
january 2013 by asterisk2a

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