warrenellis + genetics   6

Chinese scientists genetically modify human embryos : Nature News & Comment
The technique used by Huang’s team involves injecting embryos with the enzyme complex CRISPR/Cas9, which binds and splices DNA at specific locations. The complex can be programmed to target a problematic gene, which is then replaced or repaired by another molecule introduced at the same time. The system is well studied in human adult cells and in animal embryos. But there had been no published reports of its use in human embryos.
genetics  med  sci 
april 2015 by warrenellis
Scientists in China Just Edited Genes in Human Embryos for the First Time | Motherboard
The low success rate suggests that CRISPR-Cas9 is not anywhere near ready for primetime in human embryos, according to Art​hur Caplan, head of medical ethics at New York University’s Langone Medical Center.

“This is a rather inauspicious start,” said Caplan. “The technique didn’t cleave where the scientists wanted, they got crossovers they didn’t expect—I’d say the experiment didn’t work very well.”
genetics  med  sci 
april 2015 by warrenellis
Super-Intelligent Humans Are Coming - Issue 18: Genius - Nautilus
"If only a small number of genes controlled cognition, then each of the gene variants should have altered IQ by a large chunk—about 15 points of variation between two individuals. But the largest effect size researchers have been able to detect thus far is less than a single point of IQ. Larger effect sizes would have been much easier to detect, but have not been seen."
neuro  genetics 
october 2014 by warrenellis

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