maverickny + melanoma   67

Twitter
Tumor mutational burden (TMB) correlates with T cell infiltration (CTL) in some tumors (, )
But…
melanoma  LungCancer  from twitter_favs
april 2018 by maverickny
Twitter
WOW! Dr Jeffrey S. Weber ROCKSTAR /alumn CRP at CA Pt values/Inhibi…
Immunotherapy  melanoma  from twitter_favs
march 2018 by maverickny
(429) https://twitter.com/i/web/status/952394283021201410
Just noticed that BEAT-MBM: a phase II study of VEGFi (bev) + PDL1 (atezo) for brain metas…
immunotherapy  melanoma  from twitter_favs
january 2018 by maverickny
Twitter
Our combo PD1+CTLA4 toxicity article now in print in - small N, but novel findi…
melanoma  from twitter_favs
january 2018 by maverickny
Twitter
Dr Costanza Maria Cristiani @ Magna Graecia University, Catanzaro, Italy talks about NK cell function in
Melanoma  from twitter_favs
december 2017 by maverickny
Twitter
Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Survival Gene
Melanoma  from twitter_favs
november 2017 by maverickny
Twitter
Dr Roberts- Almost 40% patient relapse after CR on dab and trem. Half of these patients relapse in brain
Melanoma  from twitter_favs
october 2017 by maverickny
Twitter
Yes. Mutational burden very high in desmoplastic which typically lack a…
melanoma  from twitter_favs
october 2017 by maverickny
Twitter
Nice retrospective data in . Similar CRs but more PRs and quicker time to response with combo Nivo/Ipi vs…
melanoma  from twitter_favs
september 2017 by maverickny
Twitter
Summary of and her student's work on & responses in (also includes…
immunotherapy  melanoma  microbiome  from twitter_favs
february 2017 by maverickny
Twitter
Overview by Cathy Wu of process of personalized neoantigen vaccine generation in .
Immunotherapy  melanoma  from twitter_favs
february 2017 by maverickny
Twitter
Novel Strategy Isolates Immune Cells in the Blood that Recognize
immunotherapy  Melanoma  from twitter_favs
march 2016 by maverickny
Instagram
RT : If you're alive two years after Rx for , your odds of living 5 yrs >90%…
melanoma  yervoy  from twitter
june 2015 by maverickny
Untitled (http://wtop.com/health/2015/05/td-expert-advises-people-stay-aware-skin-cancer/)
May is the time when we all head back to the beach or pool - time for sunscreen folks!
melanoma  from twitter
may 2015 by maverickny
Form
Join us for pt forum, w/experts speaking on immunotherapy for , , & : Chicago 10/26
Melanoma  KidneyCancer  LungCancer  from twitter_favs
september 2014 by maverickny
Amgen - Media - News Release
Updated T-Vec data in advanced RT : Data From Phase 3 Study of Talimogene Laherparepvec
melanoma  SMR13  Amgen  from twitter_favs
november 2013 by maverickny
Cell - A Landscape of Driver Mutations in Melanoma
"Driver Mutation" = Oncogenic Addiction (vs. Bystander/passenger mutation) - eg bcr-abl in CML. RE:
Melanoma  from twitter_favs
july 2012 by maverickny
Professor Kim Margolin on ipilimumab-treated patients | EJCMO.tv
RT : RT : 2011: Safety and efficacy of ipilimumab-treated patients with & brain metastasis
melanoma  ESMO  from twitter
october 2011 by maverickny
Delcath Completes NDA Submission To FDA For Chemosaturation System - Quick Facts
Delcath ($DCTH) completes FDA submission on PHP/chemosaturation for #melanoma, waits for review date: http://bit.ly/dJ9EZE
– Eric D Whitman, MD (Melanoma_doctor) http://twitter.com/Melanoma_doctor/status/19162548263718912
melanoma  via:packrati.us 
december 2010 by maverickny
scary thoughts!! | Melanoma Research Foundation
Ipi is not a magic bullet.  Ipi will not work for all patients.  The researchers are still working on the facts surrounding the best possible patient.  In every presentation I've attended with many different Melanoma leaders they will tell all that the next step in the current crop of treatment options in trials is to be able to predict which treatment will work for the individual patient.
melanoma  research  ipilimumab  bms 
december 2010 by maverickny
The roots of resistance : Nature News
Nature journal summary on two reports of BRAF acquired resistance of #melanoma. http://bit.ly/hQpZAp
– Eric D Whitman, MD (Melanoma_doctor) http://twitter.com/Melanoma_doctor/status/7581795260301312
melanoma  via:packrati.us 
november 2010 by maverickny
(500) http://http://bit.ly/hDhwhn
Nature article on BRAF resistance in , ie how PLX-4032 fails. Suggests thru alt pathways.
melanoma  from twitter_favs
november 2010 by maverickny
Melanoma Centers Mtg: BRAF Inhibition by GSK2118436, includes previously unpresented data « Eric Whitman, MD
RT @Melanoma_doctor: GSK BRAF inhibitor shows striking results in treating #melanoma, including 8/10 pts with brain mets http://bit.ly/b ...
melanoma  via:packrati.us 
november 2010 by maverickny
Melanoma Centers mtg: 2nd line melanoma therapy with PLX BRAF inhibitor « Eric Whitman, MD
RT @Melanoma_doctor: 2nd line therapy with RG7204 BRAF inhib for #melanoma, new data at melanoma ctrs mtg. http://bit.ly/b8u1VW
melanoma  via:packrati.us 
november 2010 by maverickny
Melanoma informatics session at International Melanoma Centers mtg « Eric Whitman, MD
RT @Melanoma_doctor: #melanoma informatics session at mtg; everyone agrees it's essential but most places/countries not even close... h ...
melanoma  via:packrati.us 
november 2010 by maverickny
View - ESMO - European Society for Medical Oncology
Rare to see responses in #melanoma brain mets, Ph2 data a must in future #ESMO $GSK BRAF drug http://bit.ly/aHlsfu
– Eric D Whitman, MD (Melanoma_doctor) http://twitter.com/Melanoma_doctor/status/26999913541
ESMO  melanoma  via:packrati.us 
october 2010 by maverickny
ASCO 2010 Sunday June 6: Melanoma General Poster Session « Eric Whitman, MD
RT @teamoncology: Excellent !! RT @Melanoma_doctor: My top 10 #melanoma papers from Sunday general poster session, #asco10 http://bit.ly ...
asco10  melanoma  via:packrati.us 
june 2010 by maverickny
Cell cycle regulation by the Wee1 inhibitor PD0166... [BMC Cancer. 2006] - PubMed result
G2 checkpoint abrogation by PD0166285 was demonstrated to kill cancer cells, there at a toxic highest dose of 0.5 muM in some cell lines for exposure periods of no longer than 6 hours. The deregulated cell cycle progression may have ultimately damaged the
Wee1  G2  checkpoint  melanoma  PD0166285 
november 2009 by maverickny
Zebrafish provide a model for cancerous melanoma in humans
I'll never forget a tweet from Sen John McCain moaning about how/why certain species of fish research ended up in the stimulus bill for science. The simple answer is that scientists can use fish as models for disease in humans. Zebrafish are being used
fish  models  melanoma  zebrafish  Twitter  genes 
may 2009 by maverickny
TIP30 Inhibits Lung Cancer Metastasis, Study Suggests
TIP30 may be implicated in numerous cancers including lung and melanoma
Lung  melanoma  TIP30  metastases  resistance 
may 2009 by maverickny
Onyx, Bayer close late-stage skin cancer study $$
Onyx Pharmaceuticals Inc. and partner Bayer ended a late-stage study of its drug Nexavar in skin cancer patient because the drug was not working to improve patients' overall survival rate. The companies said an independent data monitoring committee concl
nexavar  skin  cancer  melanoma  Bayer  Onyx 
april 2009 by maverickny
Influence of vascular endothelial growth factor single nucleotide polymorphisms on tumour development in cutaneous malignant melanoma
Results from this preliminary study therefore suggest that VEGF gene polymorphisms (which may be associated with differential VEGF expression) may influence tumour development in cutaneous malignant melanoma. This preliminary finding requires confirmation
cmm  cutaneous  malignant  melanoma  VEGF  Avastin  SNPs 
october 2008 by maverickny
The Wistar Institute ::
Combining natural organic atoms with metal complexes, scientists at The Wistar Institute have developed a new type of enzyme inhibitor capable of blocking a biochemical pathway that plays a key role in cancer development. Based on studies in human melano
melanoma  PI3K  cancer  oncology  tumour  cells 
september 2008 by maverickny
Gleevec Pushes Advanced Melanoma Into Remission
Malignant melanoma is almost impossible to treat and so understanding the biology of the disease may lead to improved therapies. Gleevec is known to target the KIT mutation and so the finding that KIT is mutated in melanoma would make it a logical choice
melanoma  research  Gleevec  imatinib  oncology  medicine  genes 
april 2008 by maverickny

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