jm + viruses   14

Professor Sara Sawyer's Decon Station Instructions
If you are sheltering-in-place and feel that you need to take extra precautions for a high-risk member of your household, you can decontaminate things before they come into your house.  Read on if you want to know how. This post addresses common questions that I am getting about mail, fruits, groceries, etc.

The following advice is my own, tailored for this specific situation, and is the best advice I can come up with based on the extensive biosafety training that I have received as a research scientist who works with human viruses.

(via Pam)
biosafety  viruses  covid-19  decontamination  sterilising  sterilizing  health  via:pam 
12 days ago by jm
Jen Heemstra on Remdesivir
'At this point, you’ve probably heard a ton about chloroquine and hydroxychloroquine and how they may be effective in treating COVID-19. I wanted to tell you about a different molecule that’s getting less attention but may have good potential – Remdesivir.'

How Remdesivir works to inhibit viral replication. Fascinating stuff
remdesivir  viruses  science  chemistry  medicine  drugs  covid-19  treatment 
12 days ago by jm
Nextstrain / narratives / ncov / sit-rep / 2020-03-05
This is an amazing piece of data -- phylogenetic analysis of the COVID-19 epidemic as it spreads across the globe.

'The following pages contain analysis performed using Nextstrain. Scrolling through the left-hand sidebar will reveal paragraphs of text with a corresponding visualization of the genomic data on the right-hand side. To have full genomes of a novel and large RNA virus this quickly is a remarkable achievement. These analyses have been made possible by the rapid and open sharing of genomic data and interpretations by scientists all around the world (see the final slide for a visualization of sequencing authorship).'
genetics  phylogenetics  nextstrain  covid-19  diseases  epidemics  viruses 
26 days ago by jm
A biotech firm made a smallpox-like virus on purpose. Nobody seems to care - Bulletin of the Atomic Scientists
The loosely regulated market for synthetic DNA, the normalization of synthetic orthopoxvirus research, and a large number of capable facilities and researchers creates an environment in which a rogue state, unscrupulous company, reckless scientist, or terrorist group could potentially reintroduce one of the worst microbial scourges in human history.

Unless world bodies, national governments, and scientific organizations put in place stronger safeguards on synthetic virus research, the next press release touting a new breakthrough in synthetic biology might announce that an unknown scientist in an obscure lab has successfully resurrected the smallpox virus.
smallpox  weapons  scary  diseases  biological-weapons  dna  viruses 
6 weeks ago by jm
Brain Cells Share Information With Virus-Like Capsules - The Atlantic
...a gene called Arc which is active in neurons, and plays a vital role in the brain. A mouse that’s born without Arc can’t learn or form new long-term memories. If it finds some cheese in a maze, it will have completely forgotten the right route the next day. “They can’t seem to respond or adapt to changes in their environment,” says Shepherd, who works at the University of Utah, and has been studying Arc for years. “Arc is really key to transducing the information from those experiences into changes in the brain.”

Despite its importance, Arc has been a very difficult gene to study. Scientists often work out what unusual genes do by comparing them to familiar ones with similar features—but Arc is one-of-a-kind. Other mammals have their own versions of Arc, as do birds, reptiles, and amphibians. But in each animal, Arc seems utterly unique—there’s no other gene quite like it. And Shepherd learned why when his team isolated the proteins that are made by Arc, and looked at them under a powerful microscope.

He saw that these Arc proteins assemble into hollow, spherical shells that look uncannily like viruses. “When we looked at them, we thought: What are these things?” says Shepherd. They reminded him of textbook pictures of HIV, and when he showed the images to HIV experts, they confirmed his suspicions. That, to put it bluntly, was a huge surprise. “Here was a brain gene that makes something that looks like a virus,” Shepherd says.

That’s not a coincidence. The team showed that Arc descends from an ancient group of genes called gypsy retrotransposons, which exist in the genomes of various animals, but can behave like their own independent entities.* They can make new copies of themselves, and paste those duplicates elsewhere in their host genomes. At some point, some of these genes gained the ability to enclose themselves in a shell of proteins and leave their host cells entirely. That was the origin of retroviruses—the virus family that includes HIV.
brain  evolution  retroviruses  viruses  genes  arc  gag  proteins  memory  biology 
january 2018 by jm
The World Is Getting Hacked. Why Don’t We Do More to Stop It? - The New York Times
Zeynep Tufekci is (as usual!) on the money with this op-ed. I strongly agree with the following:
First, companies like Microsoft should discard the idea that they can abandon people using older software. The money they made from these customers hasn’t expired; neither has their responsibility to fix defects. Besides, Microsoft is sitting on a cash hoard estimated at more than $100 billion (the result of how little tax modern corporations pay and how profitable it is to sell a dominant operating system under monopolistic dynamics with no liability for defects).

At a minimum, Microsoft clearly should have provided the critical update in March to all its users, not just those paying extra. Indeed, “pay extra money to us or we will withhold critical security updates” can be seen as its own form of ransomware. In its defense, Microsoft probably could point out that its operating systems have come a long way in security since Windows XP, and it has spent a lot of money updating old software, even above industry norms. However, industry norms are lousy to horrible, and it is reasonable to expect a company with a dominant market position, that made so much money selling software that runs critical infrastructure, to do more.

Microsoft should spend more of that $100 billion to help institutions and users upgrade to newer software, especially those who run essential services on it. This has to be through a system that incentivizes institutions and people to upgrade to more secure systems and does not force choosing between privacy and security. Security updates should only update security, and everything else should be optional and unbundled.

More on this twitter thread:
security  microsoft  upgrades  windows  windows-xp  zeynep-tufekci  worms  viruses  malware  updates  software 
may 2017 by jm
Global ‘Wana’ Ransomware Outbreak Earned Perpetrators [just] $26,000 So Far
As thousands of organizations work to contain and clean up the mess from this week’s devastating Wana ransomware attack, the fraudsters responsible for releasing the digital contagion are no doubt counting their earnings and congratulating themselves on a job well done. But according to a review of the Bitcoin addresses hard-coded into Wana, it appears the perpetrators of what’s being called the worst ransomware outbreak ever have made little more than USD $26,000 so far from the scam.
money  fraud  ransomware  wana  brian-krebs  bitcoin  cryptocurrency  viruses 
may 2017 by jm
Microsoft Security Essentials reporting false positives on the Bitcoin blockchain
Earlier today, a virus signature from the virus "DOS/STONED" was uploaded into the Bitcoin blockchain, which allows small snippets of text to accompany user transactions with bitcoin.  Since this is only the virus signature and not the virus itself, there apparently is no danger to users in any way.  However, MSE recognizes the signature for the virus and continuously reports it as a threat, and every time it deletes the file, the bitcoin client will simply re-download the missing blockchain.

What a heinous prank! Hilarity ensues (via gwire)
via:gwire  av  antivirus  false-positives  fp  blockchain  microsoft  bitcoin  pranks  viruses 
may 2014 by jm
Russia: Hidden chips 'launch malware attacks from irons'
Cyber criminals are planting chips in electric irons and kettles to launch spam [jm: actually, malware] attacks, reports in Russia suggest. State-owned channel Rossiya 24 even showed footage of a technician opening up an iron included in a batch of Chinese imports to find a "spy chip" with what he called "a little microphone". Its correspondent said the hidden devices were mostly being used to spread viruses, by connecting to any computer within a 200m (656ft) radius which were using unprotected Wi-Fi networks. Other products found to have rogue components reportedly included mobile phones and car dashboard cameras.
wifi  viruses  spam  malware  security  russia  china  toasters  kettles  appliances 
october 2013 by jm
A Closer Look: Email-Based Malware Attacks
'The average detection rate for these samples was 24.47 percent, while the median detection rate was just 19 percent.' That is *atrocious*. (via Tony Finch)
via:fanf  fail  malware  filtering  av  smtp  email  viruses 
june 2012 by jm
The Cybercrime Wave That Wasn’t -
MSFT researchers discover fundamental scientific failures in almost all data on cybercrime/spam/malware damages. 'In numeric surveys, errors are almost always upward: since the amounts of estimated losses must be positive, there’s no limit on the upside, but zero is a hard limit on the downside. As a consequence, respondent errors -- or outright lies -- cannot be canceled out. Even worse, errors get amplified when researchers scale between the survey group and the overall population. [...] The cybercrime surveys we have examined exhibit exactly this pattern of enormous, unverified outliers dominating the data. In some, 90 percent of the estimate appears to come from the answers of one or two individuals. In a 2006 survey of identity theft by the FTC, two respondents gave answers that would have added $37 billion to the estimate, dwarfing that of all other respondents combined.' my opinion: this is what happens when PR drives the surveys -- numbers tend to inflate to make headlines
fail  science  pr  press  cybercrime  ms  via:mark-russinovitch  data  surveys  spam  malware  viruses  phishing 
april 2012 by jm
Computer Virus Hits U.S. Drone Fleet
'Predator and Reaper crews use removable hard drives to load map updates and transport mission videos from one computer to another. The virus is believed to have spread through these removable drives.'
hmm, not quite sure how that air gap is supposed to work
air-gap  security  drones  viruses  firewalls 
october 2011 by jm
Computer gamers solve problem in AIDS research that puzzled scientists for years
“This is the first instance that we are aware of in which online gamers solved a longstanding scientific problem,” writes Khatib. “These results indi­cate the potential for integrating video games [like FoldIt] into the real-world scientific process: the ingenuity of game players is a formidable force that, if properly directed, can be used to solve a wide range of scientific problems.”
foldit  gaming  games  science  biology  aids  viruses  protease  protein-folding  proteins  vr 
september 2011 by jm
Signature-based AV is failing
on average across the AV industry, 40% block rates just after 0-hour of a new malware sample, rising to 60% after 5 days. sounds like the AV industry is losing, if this chart is valid. (via Terry Zink)
via:tzink  malware  av  fail  accuracy  detection  false-negatives  scanners  viruses  from delicious
june 2010 by jm

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