jm + sleep-apnea   1

White Matter Integrity in Obstructive Sleep Apnea before and after Treatment
Sleep Apnea causes physical damage to the brain, particularly in white matter fibre integrity. Thankfully, it is reversible.
Results in pre-treatment OSA patients showed impairments in most cognitive areas, mood and sleepiness that were associated with diffuse reduction of WM fiber integrity reflected by diminished fractional anisotropy (FA) and mean diffusivity (MD) in multiple brain areas. After 3 months of CPAP, only limited changes of WM were found. However, over the course of 12 months CPAP treatment, an almost complete reversal of WM abnormalities in all the affected regions was observed in patients who were compliant with treatment. Significant improvements involving memory, attention, and executive-functioning paralleled WM changes after treatment.
brain  brain-damage  sleep  sleep-apnea  snoring  medicine  papers 
8 days ago by jm

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