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Experts raise eyebrows at digital pill to monitor patients with schizophrenia | Ars Technica
Pill reports when it’s ingested in patients who may have delusions of being spied on.
The Food and Drug Administration announced its approval Monday for the first digital medicine—a melding of a long-standing drug for schizophrenia—Abilify (aripiprazole tablets)—with an edible sensor that reports when it’s ingested. Together, they make Abilify MyCite.
surveillance  schizophrenia  psychiatry  via:rgl7194 
19 days ago by zachwtaylor
A Similar but Distinctive Pattern of Impaired Cortical Excitability in First-Episode Schizophrenia and ADHD
"First-episode schizophrenia (FE-SZ) and attention deficit hyperactivity disorder (ADHD) are both neuropsychiatric disorders associated with an impaired dopaminergic transmission.

Though displaying different clinical phenotypes, a common pathophysiological pathway is discussed controversially. Several studies using transcranial magnetic stimulation (TMS) revealed abnormalities in human motor cortex excitability in both schizophrenia and ADHD patients. Studies on cortical excitability comparing these two diseases directly are lacking."
adhd  schizophrenia  via:jaypcross 
19 days ago by zachwtaylor
Getting a Knack for NAC
In this edition of The Interface, we discuss N-acetyl-cysteine, or NAC, a precursor to the amino acid cysteine. Through cysteine, NAC plays a notable metabolic role in the body's general antioxidant activities as well as in regulating the glutamatergic system (i.e., reward/reinforcement). Because of these functions, NAC may have a therapeutic influence on psychiatric syndromes that are either characterized by oxidative stress or impulsivity/compulsivity.
N-Acetyl-Cysteine  NAC  cysteine  metabolism  schizophrenia  bipolar  antioxidants 
6 weeks ago by askium
Philip K Dick - Schizophrenia and The Book of Changes
The preschizophrenic personality is generally called "schizoid affective", which means that as an adolescent he still hopes that he won't have to ask the cute chick (or boy) in the next row for a date. Speaking in terms of my own schizoid-affective experience, one gazes at her for a year or so, mentally detailing all possible outcomes; the good ones go under the rubric "daydreams," the bad ones under "phobia." This bipolar internal war goes on endlessly; meanwhile the actual girl has no idea you're alive (and guess why: You're not). If the phobias win out (suppose I ask her and she says, "With you?" etc.), then the schizoid-affective kid physically bolts from the classroom with agoraphobia, which gradually widens into true schizophrenia avoidance of all human contact, or withdraws into phantasy

What has happened will repeat itself again and again, wherever the kid runs head on into the koinos kosmos. And these are the years (fifteen years old to twenty-two) when he can no longer keep from running into it on almost every occasion. (Phone the dentist, Charley, and make an appointment to get that cavity patched, etc.) The idios kosmos is leaking away; he is gradually being thrust out of the postwomb womb.
schizophrenia  lsd  divination  incel 
6 weeks ago by zachwtaylor
Delusions of control in schizophrenia: Resistant to the mind's best trick? - PubMed - NCBI
Here, an alternative view is proposed: Control delusions might be triggered by an even more veridical perception of the temporal order of intentions and actions. This hypothesis is supported by evidence that (a) conscious intentions in healthy subjects are often based on retrospective inferences, (b) temporal recalibrations of conscious percepts occur in healthy subjects and are disturbed in schizophrenia and

(c) basic perceptual functions of schizophrenic patients are less influenced by expectations and therefore they can sometimes be closer to physical reality than those of healthy subjects.
psychology  schizophrenia 
7 weeks ago by zachwtaylor
Tibet: Nechung Oracle Advisory | Pulitzer Center
"Dealing with Nechung is by no means easy," the Dalai Lama wrote in his autobiography. "It takes time and patience during each encounter before he will open up. He is very reserved and austere, just as you would imagine a grand old man of ancient times to be."
buddhism  schizophrenia 
7 weeks ago by zachwtaylor
Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial: American Journal of Psychiatry: Vol 0, No 0
> After 6 weeks of treatment, compared with the placebo group, the CBD group had lower levels of positive psychotic symptoms (PANSS: treatment difference=−1.4, 95% CI=−2.5, −0.2) and were more likely to have been rated as improved (CGI-I: treatment difference=−0.5, 95% CI=−0.8, −0.1) and as not severely unwell (CGI-S: treatment difference=−0.3, 95% CI=−0.5, 0.0) by the treating clinician.
schizophrenia  CBD  psychiatry  RCT 
9 weeks ago by porejide
Consciousness Began When the Gods Stopped Speaking: Julian Jaynes’ Famous 1970s Theory
Julian Jaynes was living out of a couple of suitcases in a Princeton dorm in the early 1970s. He must have been an odd sight there among the undergraduates, some of whom knew him as a lecturer who taught psychology, holding forth in a deep baritone voice.
consciousness  julian  jaynes  language  metaphor  mind  neuroscience  perception  religion  schizophrenia  stream 
12 weeks ago by therourke

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