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Hearing impairment is much more common in those with diabetes than without diabetes. Research shows diabetes increases the risk for hearing sensorineural loss in a way similar to the effects of other neuropathies through demyelination of auditory nerve fibers causing damage. In addition microvascular changes can occur in the cochlea that create thickening of blood vessels causing changes in blood flow and further damage to the nerves of the inner ear. (Rinker, 2014; Disogra, 2017) Hearing loss does not increase the risk for diabetes, however, this complication can make management difficult due to problems understanding verbal instructions. It can also cause increases in fatigue, depression, and stress due to trying to understand what is being said in everyday life, as well as in health care related interactions. (Disogra, 2017)
diabetes  hearing  loss  circulation  neuropathy  demyelinating  microvascular  damage  correlation  progression 
3 days ago by Michael.Massing
Tabs that show the theory behind songs - Hooktheory
Harmonic analyses of popular songs that anyone can add, edit, and discuss.
music  theory  chord  progression 
10 days ago by cla
The Tumor Microenvironment Innately Modulates Cancer Progression | Cancer Research
Cancer development and progression occurs in concert with alterations in the surrounding stroma. Cancer cells can functionally sculpt their microenvironment through the secretion of various cytokines, chemokines, and other factors. This results in a reprogramming of the surrounding cells, enabling them to play a determinative role in tumor survival and progression. Immune cells are important constituents of the tumor stroma and critically take part in this process. Growing evidence suggests that the innate immune cells (macrophages, neutrophils, dendritic cells, innate lymphoid cells, myeloid-derived suppressor cells, and natural killer cells) as well as adaptive immune cells (T cells and B cells) contribute to tumor progression when present in the tumor microenvironment (TME). Cross-talk between cancer cells and the proximal immune cells ultimately results in an environment that fosters tumor growth and metastasis. Understanding the nature of this dialog will allow for improved therapeutics that simultaneously target multiple components of the TME, increasing the likelihood of favorable patient outcomes.
tumor_microenvironment  progression  Metastasis 
23 days ago by Segalllab
Philip Guo - A Five-Minute Guide to Ph.D. Program Applications
If you spend five minutes reading this article, you'll learn how to make your Ph.D. program application the strongest possible. Why five minutes? Because it's probably the longest that anyone will spend reading your application.
techtariat  grad-school  phd  advice  transitions  career  progression  hi-order-bits  cs  init 
9 weeks ago by nhaliday
17 Reasons NOT To Be A Manager –
Don't get so easy a new job
Have limited power/skills always need other people
Good things are handed over to other persons, bad you are responsable
management  career  programming  careers  progression  not  a  manager  via:popular 
9 weeks ago by rauschen

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