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Commentary: Predictions and the brain: how musical sounds become rewarding
did i just learn something big?

Prerecorded music has ABSOLUTELY NO
SURVIVAL reward. Zero. It does not help
with procreation (well, unless you're the
one making the music, then you get
endless sex) and it does not help with
individual survival.
As such, one must seriously self test
(n=1) prerecorded music actually holds
you back.
If you're reading this and you try no
music for 2 weeks and fail, hit me up. I
have some mind blowing stuff to show
you in how you can control others with
study  psychology  cog-psych  yvain  ssc  models  speculation  music  art  aesthetics  evolution  evopsych  accuracy  meta:prediction  neuro  neuro-nitgrit  neurons  error  roots  intricacy  hmm  wire-guided  machiavelli  dark-arts  predictive-processing  reinforcement 
9 weeks ago by nhaliday
ZIP It: Neural Silencing Is an Additional Effect of the PKM-Zeta Inhibitor Zeta-Inhibitory Peptide.
Protein kinase M ζ (PKMζ), an atypical isoform of protein kinase C, has been suggested to be necessary and sufficient for the maintenance of long-term potentiation (LTP) and long-term memory (LTM). This evidence is heavily based on the use of ζ inhibitory peptide (ZIP), a supposed specific inhibitor of PKMζ that interferes with both LTP and LTM. Problematically, both LTP and LTM are unaffected in both constitutive and conditional PKMζ knock-out mice, yet both are still impaired by ZIP application, suggesting a nonspecific mechanism of action. Because translational interference can disrupt neural activity, we assessed network activity after a unilateral intrahippocampal infusion of ZIP in anesthetized rats. ZIP profoundly reduced spontaneous hippocampal local field potentials, comparable in magnitude to infusions of lidocaine, but with a slower onset and longer duration. Our results highlight a serious confound in interpreting the behavioral effects of ZIP. We suggest that future molecular approaches in neuroscience consider the intervening level of cellular and systems neurophysiology before claiming influences on behavior.
memory  brain  neuroscience  neurons 
april 2018 by cessationoftime
Eliminative materialism - Wikipedia
Eliminative materialism (also called eliminativism) is the claim that people's common-sense understanding of the mind (or folk psychology) is false and that certain classes of mental states that most people believe in do not exist.[1] It is a materialist position in the philosophy of mind. Some supporters of eliminativism argue that no coherent neural basis will be found for many everyday psychological concepts such as belief or desire, since they are poorly defined. Rather, they argue that psychological concepts of behaviour and experience should be judged by how well they reduce to the biological level.[2] Other versions entail the non-existence of conscious mental states such as pain and visual perceptions.[3]

Eliminativism about a class of entities is the view that that class of entities does not exist.[4] For example, materialism tends to be eliminativist about the soul; modern chemists are eliminativist about phlogiston; and modern physicists are eliminativist about the existence of luminiferous aether. Eliminative materialism is the relatively new (1960s–1970s) idea that certain classes of mental entities that common sense takes for granted, such as beliefs, desires, and the subjective sensation of pain, do not exist.[5][6] The most common versions are eliminativism about propositional attitudes, as expressed by Paul and Patricia Churchland,[7] and eliminativism about qualia (subjective interpretations about particular instances of subjective experience), as expressed by Daniel Dennett and Georges Rey.[3] These philosophers often appeal to an introspection illusion.

In the context of materialist understandings of psychology, eliminativism stands in opposition to reductive materialism which argues that mental states as conventionally understood do exist, and that they directly correspond to the physical state of the nervous system.[8][need quotation to verify] An intermediate position is revisionary materialism, which will often argue that the mental state in question will prove to be somewhat reducible to physical phenomena—with some changes needed to the common sense concept.

Since eliminative materialism claims that future research will fail to find a neuronal basis for various mental phenomena, it must necessarily wait for science to progress further. One might question the position on these grounds, but other philosophers like Churchland argue that eliminativism is often necessary in order to open the minds of thinkers to new evidence and better explanations.[8]
concept  conceptual-vocab  philosophy  ideology  thinking  metameta  weird  realness  psychology  cog-psych  neurons  neuro  brain-scan  vocab  reduction  complex-systems  cybernetics  wiki  reference  parallax  truth  dennett  within-without  the-self  subjective-objective  absolute-relative  deep-materialism  new-religion  identity  analytical-holistic  systematic-ad-hoc  science  theory-practice  theory-of-mind  applicability-prereqs  nihil 
april 2018 by nhaliday
about – Greg Dunn Design
I enjoy Asian art. I particularly love minimalist scroll and screen painting from the Edo period in Japan. I am also a fan of neuroscience. Therefore, it was a fine day when two of my passions came together upon the realization that the elegant forms of neurons (the cells that comprise your brain) can be painted expressively in the Asian sumi-e style. Neurons may be tiny in scale, but they posess the same beauty seen in traditional forms of the medium (trees, flowers, and animals).

I admire the Japanese, Chinese, and Korean masters because of their confidence in simplicity. I try to emulate this idea.

In October 2011 I finished my doctorate in Neuroscience at University of Pennsylvania. Since then I have been devoting my time to painting. When I’m not doing this I’m enjoying reading scientific papers, playing music and watching “How Its Made”.
asian  art  neurons  brain  neuroscience  Greg  Dunn  Brian  Edwards  Will  Drinker  David  Haldeman 
april 2018 by gdw

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