nanoparticle   137

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OSA | Laser coloration of metals in visual art and design
Some sort of way of using a single laser to multicolor metal coloring using not just classic laser oxidation or periodic grating, but also some sort of subwavelength nanoparticle surface treatment
laser  oxidation  periodic  grating  subwavelength  nanoparticle  surface  treament  metal  coloring  color  materials  science  research  technology 
22 days ago by asteroza
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy
TLR agonists to polarize M2 to M1 on a nanoparticle. Did not use breast cancer and just skin

Tumour-associated macrophages (TAMs) are abundant in many cancers, and often display an immune-suppressive M2-like phenotype that fosters tumour growth and promotes resistance to therapy. Yet macrophages are highly plastic and can also acquire an anti-tumourigenic M1-like phenotype. Here, we show that R848, an agonist of the toll-like receptors (TLRs) TLR7 and TLR8 identified in a morphometric-based screen, is a potent driver of the M1 phenotype in vitro and that R848-loaded β-cyclodextrin nanoparticles (CDNPs) lead to efficient drug delivery to TAMs in vivo. As a monotherapy, the administration of CDNP-R848 in multiple tumour models in mice altered the functional orientation of the tumour immune microenvironment towards an M1 phenotype, leading to controlled tumour growth and protecting the animals against tumour rechallenge. When used in combination with the immune checkpoint inhibitor anti-PD-1, we observed improved immunotherapy response rates, also in a tumour model resistant to anti-PD-1 therapy. Our findings demonstrate the ability of rationally engineered drug–nanoparticle combinations to efficiently modulate TAMs for cancer immunotherapy.
macrophage_polarization  TLRs  nanoparticle 
11 weeks ago by Segalllab
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Using mag fields to align magnetic nanoparticles in an electrode to improve electron paths, for higher peak battery output.
materials  science  research  technology  battery  energy  storage  lithium  ion  magnetic  nanoparticle  alignment  electrode  electron  path  management  peak  discharge 
october 2018 by asteroza
In situ tribochemical formation of self-lubricating diamond-like carbon films - ScienceDirect
So rubbing palladium-gold alloys in teh presence of carbon containing stuff makes very slippery diamond-like carbon films without an expensive plasma furnace, and might be suitable for mass production use
palladium  gold  nanoparticle  amorphous  diamond  carbon  film  nanocomposite  lubricant  materials  science  research  technology  tribochemical  production  process 
august 2018 by asteroza
The optical duality of tellurium nanoparticles for broadband solar energy harvesting and efficient photothermal conversion | Science Advances
Putting the tellurium nanoparticles directly in the water sounds like a bad plan for an industrial process, but this might lead to a better solid absorber for a thermal receiver?
tellurium  nanoparticle  broadband  solar  absorber  materials  science  research  technology  nanophotonic  photothermal  water  evaporation  seawaer  thermal  desalination  distillation 
august 2018 by asteroza
IFEs batteriforskere har knekt batteri-kode: Kan revolusjonere rekkevidde og levetid — IFE
SiliconX, aka IFE silicon alloy, a silicon nanoparticle composite, might be a future battery anode
batery  anode  materials  science  research  technology  SiliconX  silicon  nanoparticle  composite  IFE  alloy 
july 2018 by asteroza
Enrichment of molecular antenna triplets amplifies upconverting nanoparticle emission | Nature Photonics
apparently the lanthanide was upconverting 3 IR photons into a single visible light photon, but also seems to self destruct.
frequency  converter  upconverter  nanoparticle  organic  dye  lanthanide  doping  UCNP  materials  science  research  technology 
april 2018 by asteroza

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