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A Landmark Study on the Origins of Alcoholism - The Atlantic
That is exactly what the team did next. They compared the alcohol-preferring and sugar-preferring rats and looked for differences in the genes that were active in their brains. They focused on six regions that are thought to be involved in addiction, and found no differences in five. “But in the sixth, we did,” says Heilig. “And it made me smile because I started out doing my Ph.D. on the amygdala.”

The amygdala is an almond-shaped region that sits deep within the brain, and is heavily involved in processing emotions. When Augier looked at the amygdala of alcoholic rats, he found signs of unusually low activity in several genes, all of which are linked to a chemical called GABA.

GABA is a molecular red light: Certain neurons make and release it to stop their neighbors from firing. Once that’s done, the GABA-making neurons use an enzyme called GAT3 to pump the molecule back into themselves, so they can reuse it. But in the amygdala of alcohol-preferring rats, the gene that makes GAT3 is much less active, and makes just half the usual levels of the pump. GABA accumulates around the neighboring neurons, making them abnormally inactive.
science  medical  health  biology  rationalthinker  rational 
5 hours ago by dstelow
Blausen Medical: The source and creator of the world's large...
Blausen Medical: The source and creator of the world’s largest award-winning 3D Medical Animation and Scientific Animation library. Redefining Patient...
anatomy  medical 
20 hours ago by ingekuijper
Teardown: Box of Pain (Gom Jabbar) | Hackaday
The “Breo iPalm520 Acupressure Hand Massager”: You’re supposed to stick your hand into it, and through unknown machinations it performs some kind of pressure massage complete with heating action.
hackaday  pneumatics  air  massage  medical 
yesterday by cyberchucktx
This giant demon plant gives you burns if you touch it, and it's spreading | Popular Science
This horrifying nightmare of a plant mostly grows in the northeastern part of the U.S., but recently it’s been spreading. Folks recently found a patch of giant hogweed in Virginia, considerably farther south than the plant has crept in the past. Unlike many other invasive species, it’s not just harmful to the environment—it’s directly harmful to humans.
weed  sunburn  science  medical 
2 days ago by bwiese
The '8 Hours of Sleep' Rule Is a Myth. Here's What You Should Do Instead
Just implementing these two simple habits can immediately provide a high ROI for your sleep: Create a pre-sleep routine, focus on sound.

Decide what time you need to wake up. Block out 8.5 hours from that time. Carve out 90 minutes before the 8.5 hours of bedtime begins. Use that 90 minutes to wind down from the day (no work or stimulating activity with electronics).
3 days ago by zephyr777
The Only 10 Foods That All Nutritionists Recommend
we sent out a mass email to 17 nutritionists and doctors from all different backgrounds and asked them to name the foods they consider the healthiest. Then we cross-referenced their feedback and put together this master list. Let's put an end to the guessing once and for all—these are the foods that 100% of nutritionists can agree on.

blueberries, leafy greens, avocados, beans, garlic, lemon, chia seeds, sprouts, quinoa, wild salmon
3 days ago by zephyr777
Open Payments Data - CMS
The Open Payments Search Tool is used to search payments made by drug and medical device companies to physicians and teaching hospitals.  doctor  big.pharma  medical 
4 days ago by KnockThump

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