genetics   20412

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De Bruijn Sequences - Hamiltonians - DataGenetics
"What is the shortest sequence of numbers that we can go through in order to ensure that all possible combinations of the digits are seen? Is it possible to create a sequence that does not repeat any sub-sequence of codes?

"The mathematics, number theory, combinatronics and logic of these types of problems were studied extensively by a Dutch Professor called Nicolaas Govert de Bruijn (9 July 1918 – 17 February 2012).

"Sequences of these numbers are named after him as De Bruijn Sequences.

"The quick answer is that, yes, it is possible to make a non-repeating sequence of numbers that covers ever sub-sequence internally, just once."

Other uses: DNA genome sequencing, 2D/3D/nD surface mapping (Anoto digital paper), rotary/linear encoders, Hamiltonian Path, card tricks, more

Hamiltonian Path:
probability  randomness  sequence  codes  cypher  combinations  permutations  DeBruijn  Gold  Barker  math  programming  compression  Hamiltonian  DNA  genome  genetics 
19 days ago by Tonti
EXCLUSIVE: Chinese scientists are creating CRISPR babies
Favorite tweet:

Scoop from @antonioregalado: Chinese scientists are creating CRISPR babies

— James Temple (@jtemple) November 26, 2018
genetics  ethics  CRISPR  from instapaper
20 days ago by jeremyhiggs
CRISPR gene-edited babies are here, Chinese scientist says - Vox
He Jiankui says he helped make the world’s first genetically edited babies: twin girls whose DNA he altered to reduce the risk of HIV.
20 days ago by jorgebarba
Genetic Memory: How We Know Things We Never Learned - Scientific American Blog Network
I met my first savant 52 years ago and have been intrigued with that remarkable condition ever since. One of the most striking and consistent things in the many savants I have seen is that that they clearly know things they never learned.
memory  genetics 
21 days ago by flyingcloud
Phobias may be memories passed down in genes from ancestors
Memories may be passed down through generations in DNA in a process that may be the underlying cause of phobias
psychology  genetics 
21 days ago by flyingcloud
23andMe vs. AncestryDNA: What's the difference? | PCWorld
AncestryDNA and 23andMe are the world’s most popular DNA tests. Combined, the companies have tested the DNA of more than 15 million people, according to the International Society of Genetic Geneology.
Archive  genetics 
21 days ago by dvand5
Woman who inherited fatal illness to sue doctors in groundbreaking case | Science | The Guardian
> The woman’s father shot and killed his wife in 2007 and was convicted of manslaughter. Two years later, doctors at St George’s Hospital in south London found he had Huntington’s disease and asked him to tell his daughter about his condition and her risk of developing it. But he refused to do so because he thought she might abort the child she was carrying. The doctors accepted his decision.

In April 2010 the woman gave birth to a daughter. Four months later, she learned her father had Huntington’s disease. She was subsequently diagnosed as also having the disease. She has had to cope with the impact of the disease, and the knowledge that her daughter has a 50% chance of succumbing to it.

The woman decided to sue St George’s Healthcare NHS Trust, who she believed should have told her that she was at risk.
genetics  medicine  law  hungtington 
22 days ago by porejide
Genetics 101: What Exactly Is A Gene? – Tyler Elliot Bettilyon – Medium
Specifically, I wrote code that can do 5 things:
Generate a random sequence of base pairs, generated codon by codon, which is capped on either end by a start/stop codon.
Convert a sequence of base pairs to its corresponding amino acid sequence (assuming the sequence’s length is a multiple of 3).
Convert a sequence of single letter amino acids, like “NLYIQWLKDGGPSSGRPPPS” for Trp Cage, into the full amino acid names. (Mostly so that I didn’t have to translate it by hand for Trp Cage mentioned earlier in the article)
Given a single letter amino acid sequence, randomly generate a string of base pairs that maps to that amino acid sequence. And finally,
Given a single letter amino acid sequence, report how many different combinations of codons can be used to encode that amino acid sequence.
genetics  python 
23 days ago by euler

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