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Lynn Margulis | West Hunter
Margulis went on to theorize that symbiotic relationships between organisms are the dominant driving force of evolution. There certainly are important examples of this: as far as I know, every complex organism that digests cellulose manages it thru a symbiosis with various prokaryotes. Many organisms with a restricted diet have symbiotic bacteria that provide essential nutrients – aphids, for example. Tall fescue, a popular turf grass on golf courses, carries an endosymbiotic fungus. And so on, and on on.

She went on to oppose neodarwinism, particularly rejecting inter-organismal competition (and population genetics itself). From Wiki: [ She also believed that proponents of the standard theory “wallow in their zoological, capitalistic, competitive, cost-benefit interpretation of Darwin – having mistaken him… Neo-Darwinism, which insists on [the slow accrual of mutations by gene-level natural selection], is in a complete funk.”[8] ‘

...

You might think that Lynn Margulis is an example of someone that could think outside the box because she’d never even been able to find it in the first place – but that’s more true of autistic types [like Dirac or Turing], which I doubt she was in any way. I’d say that some traditional prejudices [dislike of capitalism and individual competition], combined with the sort of general looniness that leaves one open to unconventional ideas, drove her in a direction that bore fruit, more or less by coincidence. A successful creative scientist does not have to be right about everything, or indeed about much of anything: they need to contribute at least one new, true, and interesting thing.

https://westhunt.wordpress.com/2017/11/25/lynn-margulis/#comment-98174
“A successful creative scientist does not have to be right about everything, or indeed about much of anything: they need to contribute at least one new, true, and interesting thing.” Yes – it’s like old bands. As long as they have just one song in heavy rotation on the classic rock stations, they can tour endlessly – it doesn’t matter that they have only one or even no original members performing. A scientific example of this phenomena is Kary Mullins. He’ll always have PCR, even if a glowing raccoon did greet him with the words, “Good evening, Doctor.”

Nobel Savage: https://www.lrb.co.uk/v21/n13/steven-shapin/nobel-savage
Dancing Naked in the Mind Field by Kary Mullis

jet fuel can't melt steel beams: https://westhunt.wordpress.com/2017/11/25/lynn-margulis/#comment-98201
You have to understand a subject extremely well to make arguments why something couldn’t have happened. The easiest cases involve some purported explanation violating a conservation law of physics: that wasn’t the case here.

Do I think you’re a hotshot, deeply knowledgeable about structural engineering, properties of materials, using computer models, etc? A priori, pretty unlikely. What are the odds that you know as much simple mechanics as I do? a priori, still pretty unlikely. Most likely, you’re talking through your hat.

Next, the conspiracy itself is unlikely: quite a few people would be involved – unlikely that none of them would talk. It’s not that easy to find people that would go along with such a thing, believe it or not. The Communists were pretty good at conspiracy, but people defected, people talked: not just Whittaker Chambers, not just Igor Gouzenko.
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16 days ago by nhaliday
The Science of Roman History: Biology, Climate, and the Future of the Past (Hardcover and eBook) | Princeton University Press
Forthcoming April 2018

How the latest cutting-edge science offers a fuller picture of life in Rome and antiquity
This groundbreaking book provides the first comprehensive look at how the latest advances in the sciences are transforming our understanding of ancient Roman history. Walter Scheidel brings together leading historians, anthropologists, and geneticists at the cutting edge of their fields, who explore novel types of evidence that enable us to reconstruct the realities of life in the Roman world.

Contributors discuss climate change and its impact on Roman history, and then cover botanical and animal remains, which cast new light on agricultural and dietary practices. They exploit the rich record of human skeletal material--both bones and teeth—which forms a bio-archive that has preserved vital information about health, nutritional status, diet, disease, working conditions, and migration. Complementing this discussion is an in-depth analysis of trends in human body height, a marker of general well-being. This book also assesses the contribution of genetics to our understanding of the past, demonstrating how ancient DNA is used to track infectious diseases, migration, and the spread of livestock and crops, while the DNA of modern populations helps us reconstruct ancient migrations, especially colonization.

Opening a path toward a genuine biohistory of Rome and the wider ancient world, The Science of RomanHistory offers an accessible introduction to the scientific methods being used in this exciting new area of research, as well as an up-to-date survey of recent findings and a tantalizing glimpse of what the future holds.

Walter Scheidel is the Dickason Professor in the Humanities, Professor of Classics and History, and a Kennedy-Grossman Fellow in Human Biology at Stanford University. He is the author or editor of seventeen previous books, including The Great Leveler: Violence and the History of Inequality from the Stone Age to the Twenty-First Century (Princeton).
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4 weeks ago by nhaliday
If Quantum Computers are not Possible Why are Classical Computers Possible? | Combinatorics and more
As most of my readers know, I regard quantum computing as unrealistic. You can read more about it in my Notices AMS paper and its extended version (see also this post) and in the discussion of Puzzle 4 from my recent puzzles paper (see also this post). The amazing progress and huge investment in quantum computing (that I presented and update  routinely in this post) will put my analysis to test in the next few years.
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4 weeks ago by nhaliday
Frontier Culture: The Roots and Persistence of “Rugged Individualism” in the United States∗
In a classic 1893 essay, Frederick Jackson Turner argued that the American frontier promoted individualism. We revisit the Frontier Thesis and examine its relevance at the subnational level. Using Census data and GIS techniques, we track the frontier throughout the 1790–1890 period and construct a novel, county-level measure of historical frontier experience. We document the distinctive demographics of frontier locations during this period—disproportionately male, prime-age adult, foreign-born, and illiterate—as well as their higher levels of individualism, proxied by the share of infrequent names among children. Many decades after the closing of the frontier, counties with longer historical frontier experience exhibit more prevalent individualism and opposition to redistribution and regulation. We take several steps towards a causal interpretation, including an instrumental variables approach that exploits variation in the speed of westward expansion induced by prior national immigration in- flows. Using linked historical Census data, we identify mechanisms giving rise to a persistent frontier culture. Greater individualism on the frontier was not driven solely by selective migration, suggesting that frontier conditions may have shaped behavior and values. We provide evidence suggesting that rugged individualism may be rooted in its adaptive advantage on the frontier and the opportunities for upward mobility through effort.

https://twitter.com/whyvert/status/921900860224897024
https://archive.is/jTzSe
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7 weeks ago by nhaliday
Genome Editing
This collection of articles from the Nature Research journals provides an overview of current progress in developing targeted genome editing technologies. A selection of protocols for using and adapting these tools in your own lab is also included.
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7 weeks ago by nhaliday
[1709.01149] Biotechnology and the lifetime of technical civilizations
The number of people able to end Earth's technical civilization has heretofore been small. Emerging dual-use technologies, such as biotechnology, may give similar power to thousands or millions of individuals. To quantitatively investigate the ramifications of such a marked shift on the survival of both terrestrial and extraterrestrial technical civilizations, this paper presents a two-parameter model for civilizational lifespans, i.e. the quantity L in Drake's equation for the number of communicating extraterrestrial civilizations. One parameter characterizes the population lethality of a civilization's biotechnology and the other characterizes the civilization's psychosociology. L is demonstrated to be less than the inverse of the product of these two parameters. Using empiric data from Pubmed to inform the biotechnology parameter, the model predicts human civilization's median survival time as decades to centuries, even with optimistic psychosociological parameter values, thereby positioning biotechnology as a proximate threat to human civilization. For an ensemble of civilizations having some median calculated survival time, the model predicts that, after 80 times that duration, only one in 1024 civilizations will survive -- a tempo and degree of winnowing compatible with Hanson's "Great Filter." Thus, assuming that civilizations universally develop advanced biotechnology, before they become vigorous interstellar colonizers, the model provides a resolution to the Fermi paradox.
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9 weeks ago by nhaliday
The First Men in the Moon | West Hunter
But what about the future? One generally assumes that space colonists, assuming that there ever are any, will be picked individuals, somewhat like existing astronauts – the best out of hordes of applicants. They’ll be smarter than average, healthier than average, saner than average – and not by just a little.

Since all these traits are significantly heritable, some highly so, we have to expect that their descendants will be different – different above the neck. They’d likely be, on average, smarter than any existing ethnic group. If a Lunar colony really took off, early colonists might account for a disproportionate fraction of the population (just as Puritans do in the US), and the Loonies might continue to have inordinate amounts of the right stuff indefinitely. They’d notice: we’d notice. We’d worry about the Lunar Peril. They’d sneer at deluded groundlings, and talk about the menace from Earth.

https://westhunt.wordpress.com/2014/09/29/the-first-men-in-the-moon/#comment-58473
Depends on your level of technical expertise. 2 million years ago, settlement of the Eurasian temperate zone was bleeding-edge technology – but it got easier. We can certainly settle the Solar system with near-term technology, if we choose to. And you’re forgetting one of the big payoffs: gafia.
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9 weeks ago by nhaliday

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