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Mystery of why arteries harden may have been solved, say scientists | Science | The Guardian
That, they say, makes sense: ageing, high blood pressure, smoking and fatty plaques are risk factors for stiffening of the arteries, and are linked to damage to cells, or even their DNA.
Duer stressed that individuals should continue to avoid lifestyles habits that can contribute to artery stiffening, including smoking and poor diets. Shanahan agreed. “What we don’t know is whether it is going to work on people who have already got a lot of calcification,” she said. > reversal is know via whole-food plant-based diet.
CVD  public  health  sickcare  NHS  demand  chronic  inflammation 
5 days ago by asterisk2a
'Pumping heart patch' ready for human use - BBC News
chronically sick patients live longer.
Live extension
Global Burden of Disease increased with every new life extension method.
CVD  NHS  public  health  chronic  sick  patients  sickcare  prevention  Disabled  crisis  SAD  diet  obesity  demand 
13 days ago by asterisk2a
Stroke deaths in England halved in ten years, study finds | NIHR Oxford Biomedical Research Centre
global burden of disease

The rate of people dying from strokes decreased by 55% in a decade, according to a study published in the BMJ (British Medical Journal).

Researchers from the University of Oxford analysed data from almost 800,000 adults in England admitted to hospital between 2001 and 2010.

The authors said: "Our findings show that most of the reduction in stroke mortality is a result of improved survival of patients with stroke.

"However, acute and long-term management of such patients is expensive, and the NHS is already spending about 5% of its budget on stroke care.

"By focusing on prevention and reducing the occurrence of stroke, major resources can be conserved."

The study found that death rates from strokes decreased across all age groups. In men, overall death rates dropped from 140 per 100,000 people in 2001, to 74 per 100,000 people in 2010, and in women, from 128 per 100,000 to 72 per 100,000.
stroke  sickcare  NHS  ageing  population  crisis  demographic  bubble  premature  Disabled  disability  Council  Austerity  prevention  public  health  cancer  CVD 
24 days ago by asterisk2a
Is the NHS's long-term plan workable? - BBC News
Bleak picture
Budgets for public health (including prevention) and training of nurses, doctors and other staff have not yet been set out and, if less generous than the NHS settlement, they could affect the ability of the service to deliver the long-term plan, in the view of the report authors.

And what of the short term? The watchdog paints a bleak picture.

The financial health of some trusts, it says, is getting worse.
NHS  social  care  Council  elderly  adult  long-term  plan  Theresa  May  Conservative  Austerity  chronic  sickcare  sick  population  ageing  demographics  Cancer  Obesity  CVD  diabetes  rationing  mental  health  staff  crisis  hiring  locum  CAMHS  prevention  public  Privatisation 
january 2019 by asterisk2a
How diet is changing - the good and the bad - BBC News
But on other measures, diet has not improved, the report, from the Food Standards Agency and Public Health England, says.

Fruit and vegetable consumption remains largely unchanged and is still under the recommended five-a-day level.
Fibre intake has fallen slightly, while vitamin and mineral consumption is down.

And there has been little change in oily fish intake.
UK  chronic  sick  population  obesity  public  health  prevention  Cancer  CVD  diabetes  NHS  sickcare  demand  premature  ageing  diet  western  S.A.D. 
january 2019 by asterisk2a
Are Andrew Lansley's NHS reforms being binned? - BBC News
But Nigel Edwards, the influential chief executive of the Nuffield Trust think tank, believes a "significant unpicking" of Mr Lansley's reforms are on the cards and in time they will be judged as "one of the most major public policy failures" of all time.

If that is the case, it begs the question: why did the government go to all the trouble of pushing ahead with them in the first place?
NHS  Privatisation  long-term  plan  sickcare  ageing  population  Conservative  Party  premature  chronic  sick  prevention  public  health  CVD  dementia  Cancer  Austerity  social  care  Council  elderly  CCG  GP 
january 2019 by asterisk2a
At the heart of this NHS cash boost lies a dishonesty: tax | Rafael Behr | Opinion | The Guardian
Theresa May’s boast that extra funding won’t involve tax rises should set alarm bells ringing [...] Stevens knows that £20.5bn is a lot, yet not enough. It repairs some of the damage inflicted by austerity – a problem denied for years by ministers who insisted the NHS budget was ring-fenced. That was true in a narrow technical sense. But rising costs and a displaced burden from deep cuts elsewhere imposed an unbearable strain on hospitals and GPs. [...] Phased in over five years, the £20.5bn uplift temporarily restores health spending to something like its pre-austerity trajectory. But it is unclear where the next £20.5bn comes from. Or the £20.5bn after that. The Institute for Fiscal Studies estimates that budgets should rise by 3.3% over 15 years to keep services at their current level. If the ambition is to make them better, the annual increase would be more like 5%, taking health spending to around 10% of national income. That is the level maintained by countries like the Netherlands and Sweden. May has no plan to keep Britain in that league. [...] The dishonest part is making it sound like a self-sustaining process when it is a one-off event.
NHS  Theresa  May  Conservative  Austerity  sickcare  demand  long-term  plan  demographic  bubble  chronic  sick  population  staff  staffing  crisis  Cancer  diabetes  CVD  obesity  ageing  premature 
january 2019 by asterisk2a
NHS long-term plan: Focus on prevention 'could save 500,000 lives' - BBC News
MISTAKE. PREVENTION SHOULD BE ON TOP OF THE BUDGET, NOT TAKEN AWAY FROM THE BUDGET. That after the conservatives cut prevention (Public Health)
The government and NHS England are publishing the long-waited 10-year plan for healthcare later today. From what we know so far, it aims to reduce reliance on hospitals, giving them a smaller cut of the overall budget, and puts a greater emphasis on preventing ill health. Ahead of the publication, NHS England confirmed that a third of the extra £20bn a year the NHS will receive by 2023 will be spent on GPs, community care and mental health. Its chief executive, Simon Stevens, called the plan a "practical, costed and phased route map". However, senior doctors have complained that hospitals are facing a "near-on impossible" task over the next few years.
__ https://www.bbc.co.uk/news/health-46783621 - Will NHS long-term plan deliver the goods?
++ https://www.longtermplan.nhs.uk/publication/nhs-long-term-plan/
&!
Document demands repeal of 2012 legislation on automatic tendering of care contracts https://www.theguardian.com/society/2019/jan/07/nhs-chiefs-tell-theresa-may-time-to-curb-privatisation-automatic-tendering-care-contract
&! NHS considers scrapping four-hour A&E waiting time targets Hospitals are unlikely to recover previous performance levels, health leaders believe https://www.theguardian.com/society/2019/jan/07/nhs-waiting-time-targets-minor-ailments
&! Despite extra funding, central idea of plan for NHS England is to do more with less https://www.theguardian.com/society/2019/jan/07/what-is-the-nhs-long-term-plan-and-can-it-achieve-its-aims
& Key commitments at a glance, from reducing stillbirths to diagnosing cancers earlier
https://www.theguardian.com/society/2019/jan/07/what-will-the-nhs-long-term-plan-mean-for-patients
& NHS long-term plan: Are there enough staff to make it happen?
https://www.bbc.co.uk/news/health-46782159
NHS  prevention  sickcare  demand  Austerity  ageing  premature  population  obesity  CVD  cancer  diabetes  Conservative  Theresa  May  staff  crisis  public  health  Brexit  long-term  plan 
january 2019 by asterisk2a
(1437) Obesity patients left struggling after NHS cuts - YouTube
obesity cost - 50bn economy
6bn NHS spends on obesity
- obesogenic environment
https://www.youtube.com/watch?v=ZIrZQIRxGds - Exclusive: Call for obesity to be reclassified as a 'disease'
NHS  obesity  chronic  sickcare  Austerity  environment  obesogenic  CVD  diabetes 
january 2019 by asterisk2a
Thematic review series: The Pathogenesis of Atherosclerosis. An interpretive history of the cholesterol controversy, part V: The discovery of the statins and the end of the controversy, 2006
Abstract

The first four reviews in this series (Steinberg, D. 2004. J. Lipid Res. 45: 1583–1593; Steinberg, D. 2005. J. Lipid Res. 46: 179–190; Steinberg, D. 2005. J. Lipid Res. 46: 2037–2051; Steinberg, D. 2006. J. Lipid Res. 47: 1–14) traced the gradual accumulation of evidence, evidence of several different kinds, supporting the lipid hypothesis. They tracked the history from Anitschkow's 1913 classic work on the cholesterol-fed rabbit model to the breakthrough 1984 Coronary Primary Prevention Trial, the first large, randomized, double-blind primary intervention trial showing that decreasing blood cholesterol (using cholestyramine) significantly reduces coronary heart disease events. At that point, for the first time, decreasing blood cholesterol levels became an official national public health goal. Still, only a small fraction of patients at high risk were getting appropriate cholesterol-lowering treatment, and a number of important clinical questions remained unanswered. This final review in the series traces the early studies that led to the discovery of the statins and briefly reviews the now familiar large-scale clinical trials demonstrating their safety and their remarkable effectiveness in reducing coronary heart disease morbidity and mortality.
CVD  heart-disease 
december 2018 by pierredv
Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review | BMJ Open, 2016
Conclusions High LDL-C is inversely associated with mortality in most people over 60 years. This finding is inconsistent with the cholesterol hypothesis (ie, that cholesterol, particularly LDL-C, is inherently atherogenic). Since elderly people with high LDL-C live as long or longer than those with low LDL-C, our analysis provides reason to question the validity of the cholesterol hypothesis.
CVD  LDL  heart-disease 
december 2018 by pierredv
Cholesterol and Heart Disease: Is There a Connection?
A systematic review published in 2016 found that people over 60 years old who have high LDL cholesterol live as long or longer than people with low LDL. The researchers suggest reevaluating the guidelines for heart disease prevention in older adults.
LDL  CVD  heart-disease 
december 2018 by pierredv
Statins and the Prevention of Heart Disease. | Cardiology | JAMA Cardiology | JAMA Network
"As one of the best-studied medications in randomized clinical trials, statins are proven to extend life and reduce the number of heart attacks and strokes, even among individuals with normal cholesterol levels."
statins  heart-disease  CVD 
december 2018 by pierredv
LDL-C does not cause cardiovascular disease: a comprehensive review of the current literature: Expert Review of Clinical Pharmacology: Vol 11, No 10, 2018
ABSTRACT

Introduction: For half a century, a high level of total cholesterol (TC) or low-density lipoprotein cholesterol (LDL-C) has been considered to be the major cause of atherosclerosis and cardiovascular disease (CVD), and statin treatment has been widely promoted for cardiovascular prevention. However, there is an increasing understanding that the mechanisms are more complicated and that statin treatment, in particular when used as primary prevention, is of doubtful benefit.

Areas covered: The authors of three large reviews recently published by statin advocates have attempted to validate the current dogma. This article delineates the serious errors in these three reviews as well as other obvious falsifications of the cholesterol hypothesis.

Expert commentary: Our search for falsifications of the cholesterol hypothesis confirms that it is unable to satisfy any of the Bradford Hill criteria for causality and that the conclusions of the authors of the three reviews are based on misleading statistics, exclusion of unsuccessful trials and by ignoring numerous contradictory observations.
heart-disease  LDL  cholesterol  CVD 
december 2018 by pierredv
Tax junk food high in sugar and salt, says top doctor - BBC News
England's top doctor has accused the food industry of "failing the public" and is calling for taxes on unhealthy food high in sugar and salt.
public  health  prevention  obesity  CVD  cancer  NHS  sickcare  demand  UK  diabetes  nudge 
december 2018 by asterisk2a

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