bioinformatics   6437

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Zhu, Schadt, et al. "Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation" (PLoS Biology)
Someone on twitter posted a link to this as an example of actual "data integration." Mmm... color me skeptical (here "data integration" reads to me as a synonym for "ad hoc systems biology,") but I need to read it more closely.
data-integration  bioinformatics  eric-schadt  plos-biology  research-article  systems-biology 
yesterday by arthegall
Jones, Ruzzo, Peng, Katze, "A new approach to bias correction in RNA-Seq" (Bioinformatics, 2012)
"We present a new method to measure and correct for these influences using a simple graphical model. Our model does not rely on existing gene annotations, and model selection is performed automatically making it applicable with few assumptions."
bioinformatics  research-article  rna-seq  bias-correction  graphical-models  normalization 
11 days ago by arthegall
Richardson, Watson, "The automatic annotation of bacterial genomes" (Briefings in Bioinformatics)
The discussion of errors in annotation being propagated by basing one annotation on an earlier, erroneous or hypothetical annotation is excellent.
annotation  bacteria  genomics  bioinformatics  review-article 
13 days ago by arthegall
NetPhosK 1.0 Server
Predicting phosphorylation sites for specific kinases
bioinformatics 
14 days ago by waltonjones
NetPhos 2.0 Server
Predicting phosphorylation sites
bioinformatics 
14 days ago by waltonjones

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