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Measuring fitness heritability: Life history traits versus morphological traits in humans - Gavrus‐Ion - 2017 - American Journal of Physical Anthropology - Wiley Online Library
Traditional interpretation of Fisher's Fundamental Theorem of Natural Selection is that life history traits (LHT), which are closely related with fitness, show lower heritabilities, whereas morphological traits (MT) are less related with fitness and they are expected to show higher heritabilities.

...

LHT heritabilities ranged from 2.3 to 34% for the whole sample, with men showing higher heritabilities (4–45%) than women (0‐23.7%). Overall, MT presented higher heritability values than most of LHT, ranging from 0 to 40.5% in craniofacial indices, and from 13.8 to 32.4% in craniofacial angles. LHT showed considerable additive genetic variance values, similar to MT, but also high environmental variance values, and most of them presenting a higher evolutionary potential than MT.
study  biodet  behavioral-gen  population-genetics  hmm  contrarianism  levers  inference  variance-components  fertility  life-history  demographics  embodied  prediction  contradiction  empirical  sib-study 
26 days ago by nhaliday
Comparing within- and between-family polygenic score prediction | bioRxiv
https://twitter.com/StuartJRitchie/status/1116074740475736066
https://archive.is/bQnjM
See this thread for our new study on polygenic scores within fraternal twin pairs! Main point: take extra care with polygenic scores for traits like IQ & education, because they're confounded by (what seem to be) socioeconomic status effects. Not so for traits like height & BMI.
The idea is that the parenting is caused by the parental genotype, so it gets (mis)classified as a genetic effect on the children. It's really another way of looking at "genetic nurture" - see the papers from last year.
study  bio  preprint  biodet  behavioral-gen  genetics  sib-study  GWAS  class  s-factor  iq  education  attention  disease  psychiatry  embodied  health  environmental-effects  parenting  regularizer  spearhead  multi  twitter  social  commentary  backup 
9 weeks ago by nhaliday
Sci-Hub | The genetics of human fertility. Current Opinion in Psychology, 27, 41–45 | 10.1016/j.copsyc.2018.07.011
very short

Overall, there is a suggestion of two different reproductive strategies proving to be successful in modern Western societies: (1) a strategy associated with socially conservative values, including a high commitment to the bearing of children within marriage; and(2) a strategy associated with antisocial behavior, early sexual experimentation, a variety of sexual partners, low educational attainment, low commitment to marriage, haphazard pregnancies, and indifference to politics. This notion of distinct lifestyles characterized in common by relatively high fertility deserves further empirical and theoretical study.
pdf  piracy  study  fertility  biodet  behavioral-gen  genetics  genetic-correlation  iq  education  class  right-wing  politics  ideology  long-short-run  time-preference  strategy  planning  correlation  life-history  dysgenics  rot  personality  psychology  gender  gender-diff  fisher  giants  old-anglo  tradition  religion  psychiatry  disease  autism  👽  stress  variance-components  equilibrium  class-warfare 
march 2019 by nhaliday
Links 3/19: Linkguini | Slate Star Codex
How did the descendants of the Mayan Indians end up in the Eastern Orthodox Church?

Does Parental Quality Matter? Study using three sources of parental variation that are mostly immune to genetic confounding find that “the strong parent-child correlation in education is largely causal”. For example, “the parent-child correlation in education is stronger with the parent that spends more time with the child”.

Before and after pictures of tech leaders like Jeff Bezos, Elon Musk, and Sergey Brin suggest they’re taking supplemental testosterone. And though it may help them keep looking young, Palladium points out that there might be other effects from having some of our most powerful businessmen on a hormone that increases risk-taking and ambition. They ask whether the new availability of testosterone supplements is prolonging Silicon Valley businessmen’s “brash entrepreneur” phase well past the point where they would normally become mature respectable elders. But it also hints at an almost opposite take: average testosterone levels have been falling for decades, so at this point these businessmen would be the only “normal” (by 1950s standards) men out there, and everyone else would be unprecedently risk-averse and boring. Paging Peter Thiel and everyone else who takes about how things “just worked better” in Eisenhower’s day.

China’s SesameCredit social monitoring system, widely portrayed as dystopian, has an 80% approval rate in China (vs. 19% neutral and 1% disapproval). The researchers admit that although all data is confidential and they are not affiliated with the Chinese government, their participants might not believe that confidently enough to answer honestly.

I know how much you guys love attacking EAs for “pathological altruism” or whatever terms you’re using nowadays, so here’s an article where rationalist community member John Beshir describes his experience getting malaria on purpose to help researchers test a vaccine.

Some evidence against the theory that missing fathers cause earlier menarche.

John Nerst of EverythingStudies’ political compass.
ratty  yvain  ssc  links  multi  biodet  behavioral-gen  regularizer  causation  contrarianism  education  correlation  parenting  developmental  direct-indirect  time  religion  christianity  eastern-europe  russia  latin-america  other-xtian  endocrine  trends  malaise  stagnation  thiel  barons  tech  sv  business  rot  zeitgeist  outcome-risk  critique  environmental-effects  poll  china  asia  authoritarianism  alt-inst  sentiment  policy  n-factor  individualism-collectivism  pro-rata  technocracy  managerial-state  civil-liberty  effective-altruism  subculture  wtf  disease  parasites-microbiome  patho-altruism  self-interest  lol  africa  experiment  medicine  expression-survival  things  dimensionality  degrees-of-freedom  sex  composition-decomposition  analytical-holistic  systematic-ad-hoc  coordination  alignment  cooperate-defect  politics  coalitions  ideology  left-wing  right-wing  summary  exit-voice  redistribution  randy-ayndy  welfare-state 
march 2019 by nhaliday
Heritability of life span in the Old Order Amish | Request PDF
Offspring longevity was correlated with longevity of both parents, and in more or less additive fashion.

...

We estimated heritability of life span to be 25% +/- 5%, suggesting that the additive effects of genes account for one quarter of the total variability in life span in the OOA. We conclude that longevity is moderately heritable in the OOA, that the genetic effects are additive, and that genetic influences on longevity are likely to be expressed across a broad range of ages.
study  biodet  variance-components  genetics  longevity  time  medicine  health  data  usa  northeast 
september 2018 by nhaliday
Cultural variation in cultural evolution | Proceedings of the Royal Society of London B: Biological Sciences
Cultural evolutionary models have identified a range of conditions under which social learning (copying others) is predicted to be adaptive relative to asocial learning (learning on one's own), particularly in humans where socially learned information can accumulate over successive generations. However, cultural evolution and behavioural economics experiments have consistently shown apparently maladaptive under-utilization of social information in Western populations. Here we provide experimental evidence of cultural variation in people's use of social learning, potentially explaining this mismatch. People in mainland China showed significantly more social learning than British people in an artefact-design task designed to assess the adaptiveness of social information use. People in Hong Kong, and Chinese immigrants in the UK, resembled British people in their social information use, suggesting a recent shift in these groups from social to asocial learning due to exposure to Western culture. Finally, Chinese mainland participants responded less than other participants to increased environmental change within the task. Our results suggest that learning strategies in humans are culturally variable and not genetically fixed, necessitating the study of the ‘social learning of social learning strategies' whereby the dynamics of cultural evolution are responsive to social processes, such as migration, education and globalization.

...

Western education emphasizes individual discovery and creativity, whereas East Asian education emphasizes rote learning from authority [25]. The adoption of consumer products shows less social influence in Western than East Asian countries [26]. Westerners are described as more individualistic/independent, while East Asians are described as more collectivistic/interdependent [27], dimensions which intuitively map on to asocial and social learning, respectively.

Societal background influences social learning in cooperative decision making: https://www.sciencedirect.com/science/article/pii/S1090513817303501
We demonstrate that Chinese participants base their cooperation decisions on information about their peers much more frequently than their British counterparts. Moreover, our results reveal remarkable societal differences in the type of peer information people consider. In contrast to the consensus view, Chinese participants tend to be substantially less majority-oriented than the British. While Chinese participants are inclined to adopt peer behavior that leads to higher payoffs, British participants tend to cooperate only if sufficiently many peers do so too. These results indicate that the basic processes underlying social transmission are not universal; rather, they vary with cultural conditions. As success-based learning is associated with selfish behavior and majority-based learning can help foster cooperation, our study suggests that in different societies social learning can play diverging roles in the emergence and maintenance of cooperation.
study  org:nat  anthropology  cultural-dynamics  sapiens  pop-diff  comparison  sociality  learning  duplication  individualism-collectivism  n-factor  europe  the-great-west-whale  china  asia  sinosphere  britain  anglosphere  strategy  environmental-effects  biodet  within-without  auto-learning  tribalism  things  broad-econ  psychology  cog-psych  social-psych  🎩  🌞  microfoundations  egalitarianism-hierarchy  innovation  creative  explanans  education  culture  curiosity  multi  occident  cooperate-defect  coordination  organizing  self-interest  altruism  patho-altruism  orient  ecology  axelrod 
may 2018 by nhaliday
Harnessing Evolution - with Bret Weinstein | Virtual Futures Salon - YouTube
- ways to get out of Malthusian conditions: expansion to new frontiers, new technology, redistribution/theft
- some discussion of existential risk
- wants to change humanity's "purpose" to one that would be safe in the long run; important thing is it has to be ESS (maybe he wants a singleton?)
- not too impressed by transhumanism (wouldn't identify with a brain emulation)
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april 2018 by nhaliday
Why Sex? And why only in Pairs? - Marginal REVOLUTION
The core conclusion is that mutations continue to rise with the number of sex-participating partners, but in simple Red Queen models the limiting features of the genotypes is the same whether there are two, three, or more partners.

Men Are Animals: http://www.overcomingbias.com/2018/06/men-are-animals.html
I agree with all the comments citing motility/sessility.
econotariat  marginal-rev  commentary  study  summary  economics  broad-econ  interdisciplinary  bio  biodet  deep-materialism  new-religion  eden  gender  sex  EGT  explanans  red-queen  parasites-microbiome  mutation  comparison  evolution  roots  🌞  population-genetics  genetics  marginal  equilibrium  number  ecology  whole-partial-many  uniqueness  parsimony  multi  cost-benefit  outcome-risk  uncertainty  moments  spatial  travel  explore-exploit  ratty  hanson 
january 2018 by nhaliday
Anisogamy - Wikipedia
Anisogamy is a fundamental concept of sexual dimorphism that helps explain phenotypic differences between sexes.[3] In most species a male and female sex exist, both of which are optimized for reproductive potential. Due to their differently sized and shaped gametes, both males and females have developed physiological and behavioral differences that optimize the individual’s fecundity.[3] Since most egg laying females typically must bear the offspring and have a more limited reproductive cycle, this typically makes females a limiting factor in the reproductive success rate of males in a species. This process is also true for females selecting males, and assuming that males and females are selecting for different traits in partners, would result in phenotypic differences between the sexes over many generations. This hypothesis, known as the Bateman’s Principle, is used to understand the evolutionary pressures put on males and females due to anisogamy.[4] Although this assumption has criticism, it is a generally accepted model for sexual selection within anisogamous species. The selection for different traits depending on sex within the same species is known as sex-specific selection, and accounts for the differing phenotypes found between the sexes of the same species. This sex-specific selection between sexes over time also lead to the development of secondary sex characteristics, which assist males and females in reproductive success.

...

Since this process is very energy-demanding and time consuming for the female, mate choice is often integrated into the female’s behavior.[3] Females will often be very selective of the males they choose to reproduce with, for the phenotype of the male can be indicative of the male’s physical health and heritable traits. Females employ mate choice to pressure males into displaying their desirable traits to females through courtship, and if successful, the male gets to reproduce. This encourages males and females of specific species to invest in courtship behaviors as well as traits that can display physical health to a potential mate. This process, known as sexual selection,[3] results in the development of traits to ease reproductive success rather than individual survival, such as the inflated size of a termite queen. It is also important for females to select against potential mates that may have a sexually transmitted infection, for the disease could not only hurt the female’s reproductive ability, but also damage the resulting offspring.[7]

Although not uncommon in males, females are more associated with parental care.[8] Since females are on a more limited reproductive schedule than males, a female often invests more in protecting the offspring to sexual maturity than the male. Like mate choice, the level of parental care varies greatly between species, and is often dependent on the number of offspring produced per sexual encounter.[8]

...

Since females are often the limiting factor in a species reproductive success, males are often expected by the females to search and compete for the female, known as intraspecific competition.[4] This can be seen in organisms such as bean beetles, as the male that searches for females more frequently is often more successful at finding mates and reproducing. In species undergoing this form of selection, a fit male would be one that is fast, has more refined sensory organs, and spatial awareness.[4]

Darwinian sex roles confirmed across the animal kingdom: http://advances.sciencemag.org/content/2/2/e1500983.full
Since Darwin’s conception of sexual selection theory, scientists have struggled to identify the evolutionary forces underlying the pervasive differences between male and female behavior, morphology, and physiology. The Darwin-Bateman paradigm predicts that anisogamy imposes stronger sexual selection on males, which, in turn, drives the evolution of conventional sex roles in terms of female-biased parental care and male-biased sexual dimorphism. Although this paradigm forms the cornerstone of modern sexual selection theory, it still remains untested across the animal tree of life. This lack of evidence has promoted the rise of alternative hypotheses arguing that sex differences are entirely driven by environmental factors or chance. We demonstrate that, across the animal kingdom, sexual selection, as captured by standard Bateman metrics, is indeed stronger in males than in females and that it is evolutionarily tied to sex biases in parental care and sexual dimorphism. Our findings provide the first comprehensive evidence that Darwin’s concept of conventional sex roles is accurate and refute recent criticism of sexual selection theory.

Coevolution of parental investment and sexually selected traits drives sex-role divergence: https://www.nature.com/articles/ncomms12517
Sex-role evolution theory attempts to explain the origin and direction of male–female differences. A fundamental question is why anisogamy, the difference in gamete size that defines the sexes, has repeatedly led to large differences in subsequent parental care. Here we construct models to confirm predictions that individuals benefit less from caring when they face stronger sexual selection and/or lower certainty of parentage. However, we overturn the widely cited claim that a negative feedback between the operational sex ratio and the opportunity cost of care selects for egalitarian sex roles. We further argue that our model does not predict any effect of the adult sex ratio (ASR) that is independent of the source of ASR variation. Finally, to increase realism and unify earlier models, we allow for coevolution between parental investment and investment in sexually selected traits. Our model confirms that small initial differences in parental investment tend to increase due to positive evolutionary feedback, formally supporting long-standing, but unsubstantiated, verbal arguments.

Parental investment, sexual selection and sex ratios: http://www.kokkonuts.org/wp-content/uploads/Parental_investment_review.pdf
The second argument takes the reasonable premise that anisogamy produces a male-biased operational sex ratio (OSR) leading to males competing for mates. Male care is then predicted to be less likely to evolve as it consumes resources that could otherwise be used to increase competitiveness. However, given each offspring has precisely two genetic parents (the Fisher condition), a biased OSR generates frequency-dependent selection, analogous to Fisherian sex ratio selection, that favours increased parental investment by whichever sex faces more intense competition. Sex role divergence is therefore still an evolutionary conundrum. Here we review some possible solutions. Factors that promote conventional sex roles are sexual selection on males (but non-random variance in male mating success must be high to override the Fisher condition), loss of paternity because of female multiple mating or group spawning and patterns of mortality that generate female-biased adult sex ratios (ASR). We present an integrative model that shows how these factors interact to generate sex roles. We emphasize the need to distinguish between the ASR and the operational sex ratio (OSR). If mortality is higher when caring than competing this diminishes the likelihood of sex role divergence because this strongly limits the mating success of the earlier deserting sex. We illustrate this in a model where a change in relative mortality rates while caring and competing generates a shift from a mammalian type breeding system (female-only care, male-biased OSR and female-biased ASR) to an avian type system (biparental care and a male-biased OSR and ASR).

LATE FEMINISM: https://jacobitemag.com/2017/08/01/late-feminism/
Woman has had a good run. For 200,000 years humankind’s anisogamous better (and bigger) half has enjoyed a position of desirability and safety befitting a scarce commodity. She has also piloted the evolutionary destiny of our species, both as a sexual selector and an agitator during man’s Promethean journey. In terms of comfort and agency, the human female is uniquely privileged within the annals of terrestrial biology.

But the era of female privilege is ending, in a steady decline that began around 1572. Woman’s biological niche is being crowded out by capital.

...

Strictly speaking, the breadth of the coming changes extend beyond even civilizational dynamics. They will affect things that are prior. One of the oldest and most practical definitions for a biological species defines its boundary as the largest group of organisms where two individuals, via sexual reproduction, can produce fertile offspring together. The imminent arrival of new reproductive technologies will render the sexual reproduction criteria either irrelevant or massively expanded, depending upon one’s perspective. Fertility of the offspring is similarly of limited relevance, since the modification of gametes will be de rigueur in any case. What this looming technology heralds is less a social revolution than it is a full sympatric speciation event.

Accepting the inevitability of the coming bespoke reproductive revolution, consider a few questions & probable answers regarding our external-womb-grown ubermenschen:

Q: What traits will be selected for?

A: Ability to thrive in a global market economy (i.e. ability to generate value for capital.)

Q: What material substrate will generate the new genomes?

A: Capital equipment.

Q: Who will be making the selection?

A: People, at least initially, (and who coincidentally will be making decisions that map 1-to-1 to the interests of capital.)

_Replace any of the above instances of the word capital with women, and you would have accurate answers for most of our species’ history._

...

In terms of pure informational content, the supernova seen from earth can be represented in a singularly compressed way: a flash of light on a black field where there previously was none. A single photon in the cone of the eye, at the limit. Whether … [more]
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january 2018 by nhaliday
Frontiers | Can We Validate the Results of Twin Studies? A Census-Based Study on the Heritability of Educational Achievement | Genetics
As for most phenotypes, the amount of variance in educational achievement explained by SNPs is lower than the amount of additive genetic variance estimated in twin studies. Twin-based estimates may however be biased because of self-selection and differences in cognitive ability between twins and the rest of the population. Here we compare twin registry based estimates with a census-based heritability estimate, sampling from the same Dutch birth cohort population and using the same standardized measure for educational achievement. Including important covariates (i.e., sex, migration status, school denomination, SES, and group size), we analyzed 893,127 scores from primary school children from the years 2008–2014. For genetic inference, we used pedigree information to construct an additive genetic relationship matrix. Corrected for the covariates, this resulted in an estimate of 85%, which is even higher than based on twin studies using the same cohort and same measure. We therefore conclude that the genetic variance not tagged by SNPs is not an artifact of the twin method itself.
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december 2017 by nhaliday

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