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First (unedited) version of our latest article on risks & benefits of prescribing is out! Thanks to my…
antibiotics  from twitter_favs
7 days ago by cathmnet
Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults | NEJM
> The 4-month regimen of rifampin was not inferior to the 9-month regimen of isoniazid for the prevention of active tuberculosis and was associated with a higher rate of treatment completion and better safety.
tuberculosis  antibiotics 
14 days ago by porejide
Press Announcements > FDA updates warnings for fluoroquinolone antibiotics on risks of mental health and low blood sugar adverse reactions
> The new class-wide labeling changes will require that the mental health side effects be listed separately from other central nervous system side effects and be consistent across the labeling of the fluoroquinolone class. The mental health side effects to be included in the labeling across all the fluoroquinolones are disturbances in attention, disorientation, agitation, nervousness, memory impairment and delirium.
fluoroquinolone  antibiotics  mental_illness 
5 weeks ago by porejide
Emerging sex disease MG 'could become next superbug' - BBC News
What is MG?
Mycoplasma genitalium is a bacterium that can cause inflammation of the urethra in men, causing discharge from the penis and making it painful to urinate.

In women, it can cause inflammation of the reproductive organs (womb and fallopian tubes) too, causing pain and possibly a fever and some bleeding.

You can get it by having unprotected sex with someone who has it. Condoms can prevent this spread.

It was first identified in the UK in the 1980s and is thought to affect 1-2% of the general population.

MG does not always cause symptoms and will not always need treatment, but it can be missed or mistaken for a different sexually transmitted infection, such as Chlamydia.
STD  STI  antibiotic  antibiotics  superbug  post-antibiotic 
5 weeks ago by asterisk2a
Access to sexual health clinics 'tougher' - BBC News
New figures on sexually transmitted infections in England show an increase in syphilis and gonorrhoea and a BBC investigation suggests that funding cuts are making it harder for people to access sexual health services. 0 https://www.bbc.co.uk/news/health-44353615
NHS  public  health  Austerity  Council  antibiotic  antibiotics  STD 
10 weeks ago by asterisk2a
(429) https://twitter.com/i/web/status/1002649234439581698
are extremely useful tools when used appropriately. They are powerful drugs, and overuse/inappropriate…
Antibiotics  from twitter_favs
10 weeks ago by srhymes
Antibiotic resistance crisis worsening because of collapse in supply • The Guardian
Nicola Davis:
<p>The antibiotic resistance crisis which is threatening to render many diseases untreatable is being fuelled not just by overuse of the drugs, but a fragile supply chain that is at risk of collapse, experts have warned.

The authors of a <a href="https://accesstomedicinefoundation.org/media/atmf/Antibiotic-Shortages-Stockouts-and-Scarcity_Access-to-Medicine-Foundation_31-May-2018.pdf">white paper</a> by the Dutch non-profit organisation Access to Medicine say a lack of access to specific antibiotics can lead to less appropriate drugs being prescribed for an infection, or even the use of lower doses – both of which increase the risk of antibiotic resistance – as well as delay for treatment. What’s more, they say, low stocks can lead to price hikes and mean poor quality medicines become rife.

“The right products need to reach the right patients at the right time,” said Dr Jayasree Iyer, executive director of the Access to Medicine Foundation and co-author of the report.

Among the shortages flagged is that of the common antibiotic benzathine penicillin G, which was found by to be unavailable in 39 countries in 2015, including India, Australia and the US, and is the only drug that can prevent and treat the transmission of syphilis from mother to child. The shortage, the report notes, coincided with the growing rise of syphilis in Brazil that has resulted in an uptick in babies born with congenital illnesses.

The report also cites a recent shortage of the intravenous antibiotic and antibacterial combination piperacillin-tazobactam. Caused by an explosion at a Chinese factory that produced raw materials for the medication, the situation led doctors in the UK to warn that patients were being put at risk from reliance on alternative medications, with supplies of the drug restricted to severe cases of sepsis and ventilator-acquired pneumonia.</p>


Back in 1997 the then UK science minister said to me his biggest concern was the lack of investment by pharmaceutical companies in new antibiotics, and the overuse of existing ones. Nothing has changed in over 20 years.
antibiotics 
11 weeks ago by charlesarthur
Evolution of “Nightmare Bacteria” | Infectious Diseases | JAMA | JAMA Network
> Between 2006 and 2015, the percentage of bacterial infections caused by Enterobacteriaceae nonsusceptible to extended-spectrum cephalosporins (ESBL phenotype) decreased 2% a year, while the percentage caused by carbapenem-resistant Enterobacteriaceae (CRE) decreased 15% per year, according to a recent CDC report.
antibiotics  MDR 
11 weeks ago by porejide

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