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Finding Cancer Patients Is the Pharma Industry’s Unlikely Challenge - Bloomberg
The world’s biggest pharmaceutical companies, looking to sell a new type of cancer drug that could transform treatment, are grappling with an unusual challenge: finding patients.

The new medicines aim to shrink tumors by targeting a rare genetic anomaly -- appearing in 1,500 to 5,000 patients’ tumors in the U.S. annually -- that can spur cancer’s growth. Bayer AG is out in front with a drug that could go on sale by the end of the year. Roche Holding AG is pursuing the same target.
healthcare  cancer  genomic  Foundation-One  Roche  rare-cancer  Bayer 
yesterday by PieroRivizzigno
Lack of Paid Sick Leave Increases Poverty
Research conducted by Florida Atlantic University and Cleveland State University has, for the first time, quantified the relationship between the lack of paid sick leave and poverty in the United States. The data indicates that, even when controlling for education, race, sex, marital status and employment, working adults without paid sick leave are three times more likely to have incomes below the poverty line.

Findings also show that people with no paid sick leave benefits are more likely to experience food insecurity and require welfare services. Currently, only seven states mandate that employers provide paid sick leave benefits and nearly one-third of all workers in the United States lack these protections.

“Numerous studies have shown the negative effects lack of paid sick leave has on society, but this is the first time a direct correlation has been observed between the absence of these benefits and the incidence of poverty,” said Patricia Stoddard Dare, Ph.D., associate professor of social work at Cleveland State. “This adds to the growing body of evidence that paid sick leave is a key factor in health care affordability and economic security.”

Studies published in two academic, peer-reviewed journals, Social Work in Health Care and the American Journal of Orthopsychiatry , utilized data collected from the 2015 National Health Interview Survey to assess the effect of no paid sick leave on two key indicators of poverty, income and the need to utilize welfare services. On top of being three times more likely to live below the poverty line, working adults between the ages of 18 and 64 were also nearly 1.5 times more likely to receive income support from state and county welfare programs and nearly 1.4 times more likely to receive food stamps.

The authors argue that the main reason for these correlations are the higher cost of medical expenses, lack of preventive care and missed wages incurred by individuals and families who do not have paid sick leave benefits.

“Paid sick leave benefits serve as a structural mechanism for preventing working families from becoming the working poor,” says LeaAnne DeRigne, Ph.D., associate professor of FAU’s Phyllis and Harvey Sandler School of Social Work. “Given the public investments made in welfare, food stamps and other social services, mandating paid sick leave is a clear policy lever for reducing the need for these services among millions of individuals nationally.”
poverty  workersrights  healthcare 
2 days ago by campylobacter
The absurdity of American health care pricing, in one chart
"The figure clearly demonstrates that there is significant variation in MRI prices within hospitals at single points in time,” the authors write. “For example, in January 2011, the ratio of the price of the highest volume contract (blue circles) to the price of the second highest volume contract (green triangles) is 1.39 at Hospital A and 1.65 at Hospital B.”

The theory that the researchers put forward — and a theory I find compelling — is that these prices likely reflect different insurers’ market clout. An insurance plan with lots of members can demand lower prices; they’re essentially going to Costco and buying in bulk. But a smaller insurance plan with fewer members doesn’t have that kind of leverage, and gets stuck with higher prices as a result.
healthcare  capitalism 
2 days ago by campylobacter
A Life-Saving Checklist | The New Yorker
Peter Pronovost is hardly the first person in medicine to use a checklist. But he is among the first to recognize its power to transform intensive care. Atul Gawande explains.
healthcare 
2 days ago by jackpinboard
Atul Gawande picked as CEO of Amazon, Berkshire health care company
Atul has significant insights about the nation’s healthcare delivery system.
Healthcare  from twitter
2 days ago by ecamhi
Roche pays $2.4 billion for rest of cancer expert Foundation Medicine
FMI develops tests to help doctors understand the genetic profile of patients’ tumors and guide them to effective therapies (targeted therapies, immunotherapies and clinical trials). The deal fitted very well with Roche’s position as an early leader in matching treatment to genetic profiles (of patients).

Roche pharmaceuticals head Daniel O’Day said such technology was “important to our personalized healthcare strategy as we believe molecular insights and the broad availability of high quality comprehensive genomic profiling are key enablers for the development of, and access to, new cancer treatments”.
healthcare  gene  technology  business 
2 days ago by upning
It Was Supposed to Be an Unbiased Study of Drinking. They Wanted to Call It ‘Cheers.’ - The New York Times
The study was intended to test the hypothesis that one drink a day is better for one’s heart than none, among other benefits of moderate drinking. But its design was such that it would not pick up harms, such as an increase in cancers or heart failure associated with alcohol, the investigation found.

Scientists who designed the trial were aware it was not large enough to detect a rise in breast cancer, and acknowledged to grant reviewers in 2016 that the study was focused on benefits and “not powered to identify negative health effects.”

“Clearly, there was a sense that this trial was being set up in a way that would maximize the chances of showing a positive effect of alcohol,” Dr. Collins said last week as he accepted his advisers’ recommendation to terminate the trial.

“Understandably, the alcoholic beverage industry would like to see that.”
health  statistics  cancer  healthcare 
3 days ago by cnk

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