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Top Management : Season 1 - YouTube
글로벌 대기업이랑 일하면서도 (가령 구글) 할말 다하시는 강이사님. 구글 직영 유튜브 오리지널 시리즈 #탑매니지먼트 에서 만날 수 있습니다.
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10 days ago by dalcrose
Twitter
글로벌 대기업이랑 일하면서도 (가령 구글) 할말 다하시는 강이사님. 구글 직영 유튜브 오리지널 시리즈 #탑매니지먼트 에서 만날 수 있습니다.
from twitter_favs
10 days ago by dalcrose
Twitter
...how is it any better to evangelicalism?

So often, that queer white Christians create "progressive"…
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10 days ago by brchastain
Twitter
Zasada 1- nie oceniaj ludzi po wyglądzie
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10 days ago by piotrwojcicki
Twitter
RT : Apple’s pricing is high, no doubt. But 8 weeks ago I got called by 2 tech vendors telling me OEMs are raising price…
from twitter
10 days ago by willie
Twitter
RT : The critique is about a very specific bit of usage of functions in Nixpkgs, not about functional programm…
from twitter
10 days ago by hyperfekt
Twitter
RT : Today, watch as Sinclair Ferguson clarifies the relationship between the doctrine of election and the free offer of…
from twitter
10 days ago by ewerickson
Twitter
Reading some of the discussion around the Flickr news, some people seem to like Google Photos but it seems…
from twitter
10 days ago by ghaff
Twitter
Our world is being ran by cruel corporate overlords that put money and profit over everything and anyone. Don’t bla…
from twitter
10 days ago by tielure
Twitter
RT : It's wild that Apple will buy billion-dollar TV programmes to flesh out its video offering, but won't develop a sin…
from twitter
10 days ago by willie
Twitter
But some students were mean to a Nazi troll on a campus somewhere so
bothsidesdoit  from twitter
10 days ago by jrosenau
Twitter
RT : Senate Republicans have tried over & over again to rip apart protections for people with pre-existing conditions. N…
from twitter
10 days ago by edelagrave
Twitter
Did you know Julian Bond--civil rights leader, NAACP chair, etc.--wrote an anti-Vietnam war comic in the 60's? I su…
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10 days ago by ninthart
Twitter
Guess I can't ever play RimWorld again...
from twitter
10 days ago by kennethlove
Upcoming Cases
one last test sorry this is annoying
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10 days ago by jtyost2
Twitter
Susan Molinari, a senior official at Google who leads Google’s federal lobbying and policy effort, is stepping down…
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10 days ago by girma
Twitter
Alex said he saw something on watchmojo that said Queen insisted they keep Freddie's bisexuality and his st…
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10 days ago by psiten
Twitter
This week we've moved from being referred to as the 'IT team' to being called the 'Digital team' - it's a step in t…
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10 days ago by benjystanton
Twitter
On the other hand, maybe being a bit tipsy is how you make it through the day having to listen to endless startup p…
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10 days ago by ritwik
Twitter
On the other hand, maybe being a bit tipsy is how you make it through the day having to listen to endless startup p…
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10 days ago by colmanareilly
(429) https://twitter.com/i/web/status/1058412708381552640
RT : Perfect your drifting skills and hit the nitro button to become the 16-bit champion with - the ul…
SuperPixelRacers  from twitter
10 days ago by Sabas
Twitter
RT : When a typo accidentally stumbles into the truth.
from twitter
10 days ago by edelagrave
Twitter
Need help in making your creative vision a reality? Join a community of women committed to supporting each others p…
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10 days ago by mulkey
Twitter
The response from here is pretty special...
from twitter
10 days ago by Fallingbadgers
Twitter
If you are turned away at the polls your response is:

Give
Me
A
Provisional
Ballot
With…
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10 days ago by soundsgood
Twitter
In honor of , here's a look back on my 1998 interview with Queen guitarist Brian May.

Yes, it i…
BohemianRhapsody  from twitter_favs
10 days ago by Smokler
Twitter
Ahem! Do you actually know why one requires a spouse in order to perform the Aswamedha Yaga? I mean, I'm not really…
from twitter_favs
10 days ago by kamal
Twitter
|er Zustände: die ganze Stadt voller Sticker und NS-Graffiti. stoppt antifaschistisch…
Nazi  Eisenach  from twitter_favs
10 days ago by reinhard_codes
Twitter
RT : I’m not crying. You’re crying 😢❤️
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10 days ago by psiten
Twitter
RT : Journalists must be allowed to report facts freely and independently. Canada will always demand that those who hara…
from twitter
10 days ago by edelagrave
Queer Eye for the… Male Victims of Toxic Masculinity?
H ow long until we get a release date for Season 3 of Queer Eye ? I can’t handle the anticipation. There’s so much to love about the Netflix reboot of the…
from instapaper
10 days ago by jrdodds
Twitter
Enjoyed visiting with folks at Legacy Heights and sharing my commitment to protecting Social Security and Medicare!
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10 days ago by andriak
Twitter
., no one believes that you scheduled downtime in the middle of the day on your biggest day of the week w…
from twitter
10 days ago by patrickmeast
Twitter
if you mean do I come down in the middle on the question of "is feeding and clo…
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10 days ago by patricktaylor
Twitter
There's a real danger of exvie twitter perpetuating the white supremacy it critiques within evangelical…
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10 days ago by brchastain
Twitter
"Plunging cinder block." Snicker. I'm not sure I could name another company that is so wildly successful in certain…
from twitter
10 days ago by ghaff
Twitter
Investment banks have a bunch of different businesses, asset management, advisor…
from twitter
10 days ago by rhyndes
Dahle 550 Paper Cutter | Cool Tools
“Until a couple of years ago I had struggled with different inexpensive paper cutters, but I kept finding myself going to Kinko’s and using the cutters there. Then I got smart and jotted down the brand name, Dahle 550 Rolling Trimmer Paper Cutter *$148), and bought one online.

“What I appreciate most about this cutter is that I never have to change blades, or deal with dull blades, because it’s self-sharpening. The steel rotary blade contained within the plastic safety housing moves across a stationary blade that extends the length of the cutting platform. This action hones the rotary blade, which remains constantly sharp. It’s also set up for wall mounting, which is ideal in my home office layout.”
papercutters  recommendations  cooltools  2018  paper 
10 days ago by handcoding
Guru's Lair - Sampler and Tour
We pride ourselves in having the finest PostScript-
as-language programming resources anyplace ever.
This is a superb general purpose computing language
that is easy to learn, fun to use, and has an astounding
number of uses.
postscript  tex  latex  pdf  documentation  typography  writing 
10 days ago by dusko
JPL Small-Body Database Browser
RT : 2018 UD3, 15m-33m in diameter, just passed the Earth at 7km/s, missing by 621,000km.
from twitter
10 days ago by nwhyte
Climate Change is Already Drastically Altering the World’s Climate Zones
In an article published by the Yale School of Forestry & Environmental Studies, Nicola Jones details some of the ways that the Earth’s climate zones have…
from instapaper
10 days ago by breau
Twitter
RT : Both of Marco Rubio's parents were Cuban immigrants. They were not US citizens at the time of his birth, and natura…
from twitter
10 days ago by willie
Twitter
Favorite tweet:

Incredible chart. Amazing work @TheEconomist. pic.twitter.com/dgEeSEMMZZ

— Stuart A. Thompson (@stuartathompson) November 1, 2018
10 days ago by michem
Twitter
RT : I just tried to read Bertolt Brecht’s poem “To Posterity,” written in exile in 1939, and almost couldn’t do it
from twitter
10 days ago by Iko
Twitter
The signalling as you drive out of Ontario? Personally, this stuff doesn’t bother me,…
from twitter
10 days ago by jwoodget
Checkpoint Inhibitors in Patients With mRCC | PracticeUpdate
BACKGROUND

To the authors' knowledge, outcomes and prognostic tools have yet to be clearly defined in patients with metastatic renal cell carcinoma (mRCC) who are treated with immuno-oncology (IO) checkpoint inhibitors (programmed death-ligand 1 [PD-L1] inhibitors). In the current study, the authors aimed to establish IO efficacy benchmarks in patients with mRCC and update patient outcomes in each International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) prognostic class.

METHODS

A retrospective analysis was performed using the IMDC database with data from 38 centers. It included patients with mRCC who were treated with ≥1 line of IO. Overall response rates (ORRs), duration of treatment (DOT), and overall survival (OS) were calculated. Patients were stratified using IMDC prognostic factors.

RESULTS

A total of 687 patients (90% with clear cell and 10% with non-clear cell) were included. The ORR was 27% in evaluable patients (461 patients). In patients treated with first-line nivolumab and ipilimumab (49 patients), the combination of PD-L1 inhibitor and vascular endothelial growth factor inhibitor (72 patients), and PD-L1 inhibitor (51 patients), the ORR was 31%, 39%, and 40%, respectively, and the median DOT was 8.3 months, 14.7 months, and 8.3 months, respectively. The ORR for second-line, third-line, and fourth-line nivolumab was 22%, 24%, and 26%, respectively. The median DOT was 5.7 months, 6.2 months, and 8.3 months, respectively, in the second-line, third-line, and fourth-line settings. When segregated into IMDC favorable-risk, intermediate-risk, and poor-risk groups, the median OS rates for the first-line, second-line, third-line, and fourth-line treatment settings were not reached (NR), NR, and NR, respectively (P = .163); NR, 26.7 months, and 7.4 months, respectively (P < 0. 0001); 36.1 months, 28.2 months, and 11.1 months, respectively (P = .016); and NR, NR, and 6.7 months, respectively (P = .047).

CONCLUSIONS

The ORR was not found to deteriorate from the first-line to the fourth-line of IO therapy. In the second line through fourth line, the IMDC criteria appropriately stratified patients into favorable-risk, intermediate-risk, and poor-risk groups for OS.
RCC  immunotherapy  nivolumab 
10 days ago by cnk
Twitter
Is it just me or is it weird the Democratic Party would fill in on its plans like this?
ncga  ncpol  from twitter_favs
10 days ago by andriak
Twitter
Vue core in Japan! 🎉❤️ (not all of us) First pic is us at Mount Fuji! Thank you for being such a great tour…
from twitter_favs
10 days ago by FND
Twitter
Vue core in Japan! 🎉❤️ (not all of us) First pic is us at Mount Fuji! Thank you for being such a great tour…
from twitter_favs
10 days ago by hoodwink73
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